HsaINT0003372 @ hg19
Intron Retention
Gene
ENSG00000121989 | ACVR2A
Description
activin A receptor, type IIA [Source:HGNC Symbol;Acc:173]
Coordinates
chr2:148657027-148657467:+
Coord C1 exon
chr2:148657027-148657136
Coord A exon
chr2:148657137-148657312
Coord C2 exon
chr2:148657313-148657467
Length
176 bp
Sequences
Splice sites
5' ss Seq
AGCGTAAGT
5' ss Score
10.07
3' ss Seq
TTTCCCCCCCTTTTCCACAGCCA
3' ss Score
10.94
Exon sequences
Seq C1 exon
GACTGATTGTGTAGAAAAAAAAGACAGCCCTGAAGTATATTTTTGTTGCTGTGAGGGCAATATGTGTAATGAAAAGTTTTCTTATTTTCCGGAGATGGAAGTCACACAGC
Seq A exon
GTAAGTTCACAGGGAAAATACGTAGGTTTGCTCAACTGTAGATTGGAAACAAAATATATTTGTGTTGATGGAATAATTTGCCCCTACCTCTTCCCCAAAATTTGAGACTATGACAGATATTTATTATAGAATTTTGTAGACCAAATCTGAGTTATTTTTCCCCCCCTTTTCCACAG
Seq C2 exon
CCACTTCAAATCCAGTTACACCTAAGCCACCCTATTACAACATCCTGCTCTATTCCTTGGTGCCACTTATGTTAATTGCGGGGATTGTCATTTGTGCATTTTGGGTGTACAGGCATCACAAGATGGCCTACCCTCCTGTACTTGTTCCAACTCAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121989-ACVR2A:NM_001616:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=NA C2=0.077
Domain overlap (PFAM):
C1:
PF0106418=Activin_recp=PD(33.0=78.9)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAAAGACAGCCCTGAAGTATATTTT
R:
TGGAACAAGTACAGGAGGGTAGG
Band lengths:
242-418
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)