HsaINT0003379 @ hg19
Intron Retention
Gene
ENSG00000114739 | ACVR2B
Description
activin A receptor, type IIB [Source:HGNC Symbol;Acc:174]
Coordinates
chr3:38495790-38518985:+
Coord C1 exon
chr3:38495790-38495865
Coord A exon
chr3:38495866-38518777
Coord C2 exon
chr3:38518778-38518985
Length
22912 bp
Sequences
Splice sites
5' ss Seq
CCGGTAAGA
5' ss Score
10.1
3' ss Seq
CTCTTTTCTCTGGGGCACAGGCT
3' ss Score
5.63
Exon sequences
Seq C1 exon
GTGCGCGGGGCGGCGCCGCGGAACATGACGGCGCCCTGGGTGGCCCTCGCCCTCCTCTGGGGATCGCTGTGCGCCG
Seq A exon
GTAAGAACTGGGCGCGGCGCGGGGACGCCGAGAGGGCGCGCGGGGCTGGCCTCTGGCGCCGCGCGGTGTTTACCAACAAAGGGCGGGCCCGGGGCCTCGTCGCCGCACCACCTGTATTCAGCCCTCACCTCCGGGGGCGTGGGCTGGGGGCGCGGTGGGCGCCCGGCTCGCCGAACTTGGGGGCACGATCTTGTCTGTGCAGTCATCTGCGGGATTCTGGTTCCTAGAGGCGCCCCTGCGATGGGGGCCGGGACGCGGAGCCTCAGGGTCGGAGTTCGGGCTACGCGGGCGCGTGGAACCCAGGGAAAGAGTGAGGAAAACCTGAGCGTGGGGAAGGCGGCCAAGAGGGGTGGGCAGATCTCATTGGGGGTGGCAGGATTGTAGGTGCAGCAGCAGCAGCAGCATGCGGGGAGGGTTGCATGTCCCTCAGAGTCACTAAGTGTAGCGAAGCGAAGGGGGCGGCTTCACGCAGCCCAAAGTCCCCTGCATCTCTTGCCACCAGTCTGCGTCGCGTTACCGGCCCGGCGGGCTGTTGGTGCTGGCTCCCACCTGCTCCCTCTTTCCCTGCCGTTGGCCCCGGGATGCGGAGTGTGGTCGCTTCGCGGGACCGCTTTGTTTGGGCACTTGGGAGGGGAGGGGGTGGGTAAGATGGAAAACCCAACAGGTCCCTCTTCCTTCGGGCCTCCAGGAGGCACGTGGCGGGGTGGGTGACCAGCGCTCAGCTCGCCCGCGGCTGCGGGCGTGTGGCTGGAGGTGTTCGGCCAGCGCATGTGTGTTTGGGGGTATGTGGGCGCGGGCGTAAACAAGCGGAGTTCCGCCTGGAAAGCTTGTTTCTCCTACGGTCCAAGCACCGATTTCCCTCTCTCAGTGGTGCCGGGGTGCGCCTAACCCCGGCGGGCGCGCCGGGACGTCCCCTGGCCAGTCCTGGGAAACGTGGGGAGCTGGGCATTGAAGCTCTGGCGAGAAGGTCGGGGCGGCTGGTACCCGGCCGCCGGGTCCTGCGCGTCTTTGTTCCCAGCCCCCATTACACATGCAGCGCGGGTCCCCCGCCGCCCTCGGTGGCAGCCGCCTGGAGTCTGGGAAACCCTCGAGGGGCGGGGCCGGGCGTGCAGGGGCGGGGCCGGAGTCCCCACGCTGCTGCGGGGGTGGGGATTTGGGATCTGCGTCCCATTCCCACCCTGGTTCTACCTTCTCCTGTGCGTCGTCGTGAGGCTTAGTTTACACCGAAAGCGAGTGAGTTCTGTAGGGTAGTAGCGCGCGCGCGCGCAGCCTGAGTCCGGAAACCGAAGGGCAAAGACCAGCTGGCACCTGAGTACCGTATGGAAGAGGGCGTTGCAGCTCTCCTGGAGCCGCTTCTTGGAGGCGAAGTGGTGGTCGTGTTGGACTTTCTGCTCTTTTTTGCCCCGCTCCCTTGGGATGCCTTTTCCCCAAGAAGGAGTGCTCGAAAGTGAAAGGGGAGGCATTGGTCTGCTAGAGGGAGGGCGGCAGCAAGCTGACTTGATAGGCAGACCGCAGCCCACCTGACTGCCTCCAGACCCGCTGGGTGCCTGATCCCTGGAAGTGCTGGGGCTCTTCCAAGCCCAGGCCTTTAGGAGAGCTTCCTCCCAAGACAGGACAGCTTGAGACCTGGGATCTGGGGATCACACCAGTCTCACACCTCCCTCCTTAGGCAGGGCAGGGCGGCATCAGACCCCTGGAAGGACTGTATGTCCTTTCTTTTTCCTCTGCTTCAGTCACCTAGCTTGGGCAGTGCTGAGCAGTGTACCCTGCCAGGGGGCAGTCAGAGTCACACTATAAGGACCTGTATTCCTGCCCTGGGAGGAAGGTGGGGGTCACTGGGTATTTCTTGTAGTCACATCAACCAGTCCCTGACCTGTGGAGAACTGTGAAAAGAGCTGCCCCAGGCCCAGTTTGGAGCAGACCTGACCGTCCTGTTGCTTTGGCTTCAGGGATGCCCTTTAATTTCAAGCTCCTGGCTTGCTGTTTGGAATAACCCCCATACTGTGCAGCACACAATGCCTGCTAGAAGGAACATCTAGAAGAGTGCTGTGTGACAGAAATAGTGTATGAACTATGGATAGATATAAAACAACGTTTTCTAGTAGTCGTGTTAATAAAAGGAAGAAGAAACAGCTGTGTCTTAGCTGGGGCTGCCATAACAAAATACTGTAGACTGGTGGCTTAAACAGCAGAAATTTATATTGTCAAAGTTCTGGAAGCTCTAAGTCTGAGCCCAGGGTGCAGGGTGCTGGCATGGTTGGGTTCTGGTGAGGACCCTCTTCCTGGCTTGCAGATATCTGCCTTCTTACTGCATTCTCAAATGACAGGGGTGGGGTGGGGCAAGGGGGTGTTTTCCTCTTTTTGTAAGACTGTGAATCCTGTTCTCATTACCTGATGGCCCCACCCTCATGACTTAATCTAACCCTCACTACCTCCCAAAGGTCCCGTCTCCAAATACCATTACACTGGGGGTCAGAACTTCATTGTATGAATTTTGGGGGGACACATTCTTTCCATGAGATGGAATGAACTTCAATAGTATATTTTACTGGCCTGGCACAGTGGCTCATGCCAGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCACGAGGTCAAGAGATCGAGACCATCCTGGCCAACGTGGTGAAATGCGTCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGCTGCGCCAGAGGCTGAGGCAGGGGAATGGCATGAACCCGGGAGGTAGAGGTTGCAGTGAGCCGAGATCATGTCACTGCACTGCAGCCTGGTGACAGAGTGAGGCTCCGTCTCAAAAAAAAAGTATATTTCACTGAATTTGATATATACAAAGTAATTTCAGCCTGAGATCAGTATTAAAACGAGACATTTTGCATTCCATTTTTGTACTGTCATCAAAATCCAGTGTGTGCCTTACAGAACATCCTCAACTCTAACTTTCCACATTTCCAGTGCTCTGCAGAACATTTGGTTAGTGGCTACCATATTAGACAATGGAATCTCAGAAGGGAAGGTAGAATTTATGGTGTAATAAATGTCACATGGTGCTTGTCACAAGATCAGTCAGTGGTTAGTTGGTTCTTTAATAATTCTTCAAGTCTTTTGTGGTCTGTGCTTGGCCGAGTGTCCTTGGGAAACAAGCCATTTGGCTCTTGCATTTCAGTGGACATCCTGGACACTCAATGCTGTATCCTACAAGAACTCCTGACACCTGTCTCTGTACTCTGTACTTGGGGTTCAGATCAAAGGGCTTATGGGGGTGGGGTAAACAGTATTCTAAGTGAAGTGACCAGAGCTCTTGGAGAGGGACCTGCCTCCTGTCTATCCCATCAGGAAGTGCAGGCCCTGATTACTCTGATAGGCTGACCCAAAGAAGTTTCTTGGCCACTTCCTTGGGGGAGGGCGGAGGGAGTGAGCTCATGAAGTGAAGTGACTTTCATCCCTCAGGCCTAGTGTAGCGGTAGCTGCCAAGGACATGGGCTACAGAGCCATGGGCCGTGGGTGCCCCTCCCAGAGAAGAGTGTTTTCTGCTACCTGTCCTTGTATCTGCTGGGCACTCGAGGCTCTGCCCTGTCTGGGTGGGCTGCCTTTTGGGAGGAATGGGTATCCTCCCTAGCTCTTAGGGGCCCTTTCAAGGCAGATGATGTGAGAAACCTGCCCATCTTTCCAGGCCCTATAGCTGGGTAAAAACATAAGATCTAAACCCTATGGCCTCCCATCACTTGGGTGGGCCTCTACTGTGTACTACTCTGTGGGTCTTTCTGGGCATCAAGAATCTCCAGAAGCACCTGGACCTCTGCTGGCACTTCACCTAAGGAACTCCTGTTATAAGGAGCCAATGAAGAGCCCACATTCTATACAGTGGTCCTCCATGTCATAGACCCCTCTGAGAATCTGATGAAAGCTGTGGACCCTTCCTCCAGGAAAATGTAAATCGGTATATGTGTGCATGTGTGTGTACATTGTATGCACCCACTCTGTTTTGTACAGATACTGGGAACCTACTGCCCCCTGATTAGACTCCTTGAAGTCCTGGCTGCCCTGCACATATCCACTGTAGTAGTCTTAAGGGGCAGCTTGTTCTGCGGGGGAGGGGTGCTTTTTCCACCTTGGTACCTCACTTACTTTGCCTTTTGTGATCCTGCCGGATGTTCAGATTCTAGCCCTGGTCTCTCTTTCCAGAAAGCTGTCCTCTTGAGTGCCAGCCTATGCATTCAGCCCCTCTGCTTGGGAGCTCAGGGTAGTGCAAATGAGAACCAAGGAGTATCGGTTCAGGAGTTTAGATCCACTCACGGATACTGACCTGTCACCATGGATTGGGATCTGGAGGGTTGAGGACTGGGTCTGGATAATATTTTTGCTAGTGACTGTAGATAGACTCTAGATAGTCCTGAGGCAGGGTCCTGGTTGCATGGGCCTCACTGTAGAACAGGGTTTCTCAACCTTGACACTATTACATTTTGGGCCTGATGATACTCTGTTGTGTATGGGTAGTGGTGGGTTGAGCTGTTCTGTGCATTGTAGGATATTTAGCAGTATCCCCGCCTCTACCCACAAATTCCAGTAGATCCTCTTTAATCATGTCAACCAAAAATGTTTCCAGATCTTGCTAAATGTCCCTGGCAGAGGTGAGAGCAAAATCATCTCAGATTGGGAACCACTGATCTAGAATGTTCTCACGCTTTCAAAGAGGTCTACAGTTGTAAGAAGTAGGGGTAACGGCTTTTGAGTGCATATCCATCCCCCCACTCTGGATGCAGGGTTGGAGGTGAGGTTCTCCTCAAAGCCTAGGAGATTCCTGCTTAGTGAAATCTGCTCAGCACGTGAGAGTTTGGTTCAAAATTAGTGGTTCTGGTGTACAGCTTACCACCGAGGAGAATCCTGGCGTCCTTGAGTTTTCCCAGAAGTGGTTCAGGTTTCAGGGAGGCGGAGGCTGTGGGTGGCTGGGCAGCCTGCCTGCCCGCACCCGCCCACTCGCCTCTGACCGTTGCCTTAAGGCTGGCACTCAGCCTCTTCCTCCCGTACACGCAGAAATGCCAGGAAGTGCCTGTTGCTGGGGACTCTCTGCCTGCCCAGCAGCCCCTCTCTGCTCACCTGGGGGCCTCAGGAGCTAAGGCTAGCCCTGTCTGCCAAGCGGAGCACTGGGGTTGTAGCAGGCCGTGGGCATGCCCCTTCCCCTGAGTGGACCTGCCATGTGGCGCTCCGGGGAGCCGCAGAGGCTGTGGGCCTGGAGCCCCCAGGCCGGGGACACCAGGGCAGGTGGGCAGCCTCTCCCCAAAGGTATGGGTGCAAGTCTCTCCCTCAGGGTGTGGTGGCCAGATGGGAATCTGAGGGCAGGGCCAGGCTTCCTGCTGTGGACCTGGGGAGGTGTGGGCAGCGCTGCCTTAGACAGGCAGCCGACACTGGAGGCCCTGGTGGAGCGGTTGGTATCTGTGGAGGCTTGTCTATTGGGCTTGGCAGGCTGGCAGCCCCCTGTGGCTGCCCCCATGTTTATTTTCTACTCCTCCCCTGGCCTGCTTCAAGCTTGGCTAGGGAACGCTTCTGTGGGACTCTGTCTGTCTCATCTTGAACTCAGTGAGACACAGTTTGCTGCACTGGGAAGTGATTACAAACTGGACTCTTAGGGTGGAGGAAGCATTTTTCAAAGACCCAGTTTCCAAGTGCTCCACATCACTGGTATGTGAAGTGCTTGCTGAGGTTCAGACTTCCTAGTTCCATCTGTTTTTGGGGTCTTTACAAAGGGGACTTTATTTCCTTCTCAGAATTCTTTCTCTTCCTTCCCTCCGGTTCTATCACTAATTCTGTGTTCCAAAACAGACACCCACCCCCTTGTTCTGGGCTTTCTTTTTTGGTCTCTCATTCTCTACCAGACTTACGGGTCCATCCCAGCCCTAGAGGTGCCTATTCCTTGTGGTCCTGGGGGTACTGCTACTGAATGCCCAGGTTTTCTGGTGGTGGAAATGCTGCTGCCTTCTTCTGACTCTATTACATTGCTCAGTGATGTCTCTGACTAAGGCAGTGGTAGGTACTGGAAATCAATGGATAAAGCAGGCTGGGATTGTTCAAGGGTCAGCCATGTCTCTTCCCGGCCCAGGACCAATAATGGCTTCCCGCCTTCGGACAGCCCCATGCTTTCCCCTGGTTATTCTAGGCTTGCTGTACACATGCATGTGCCTTTTTCAGATTCTTTCTGGGACTGGCAGCTCCAACTGGGTGTTTTCATTCATGGACGCATGACCTCTGGAAGCGGGTGTGGAAAGGAAGCCTGTCCCACTGGGCAAATGTGAGGCCCTCTTCCCAGGGGAATGTTGTCTGGATGGGTCTGACCTGCTGGACAATGGGCCTTCTCCCTGGCCAGTTTCTGGGCTGGAGCTGAGGTGTTTTGTGAGGCGAGCTCATGCTCTTTGCATGTGTTCCTCTGCCGACTATTTCAGTTCCACTCTGACAACCAAGGAGGCTAAAATTAGTTCTGGAGAAGGAAAAGGAAGGCTGGTTGGAAACCCAAGCCCTTGGCTGGAGAATGGAGGAGGCTGCTTCCCAGGTTTGTGCCTGAGCATTTCGGAGGATGGGATGAGACCAGCTGTTATCCGTCCATCTGAGGAGAAGGAGGGGTCCCTGTGGCCTCCCAGACTTGAACCAATTAAAACAGGAGACTAACTTGGAAGCTGACTCTCTCGAGTGTTGATGCCAGGATATTTTTTCCTTCTGGCTTGTGCAGTGGCGCACAGTGTTTTCAGGTATGAGGACAATGCCTTTTAATGAATGTCCAGTGCCATTGACAACCCTCCTCCCCCTCCCCTCCAACTGGATTATGTGTCCGTTGATTTAGAAAGCATGCATGAGTTTTCCCAGCCTGGGCTGGCAACCATGGTTTAAGAACTCTTATTTTATGCACTTTTTGGGAATTTCCTTCTCACTGAGGTTTGATATTGGGTTAGAGGGGAGTCCTGTGGCCCAGGGCTCACACAAGAGGTCCCGCTTCTCTGTGTAGTGAGGGCATAGTGAATCAAGGCTCATCTGCTCTGGGCCTTAGAAACCAGAGGAGCAGAAGGGTTAGAGAGATGAATTCTGGTTTCTTTTCCCACCTGGCTGGCTCCTTCTGTGAACCTTCTGGCTGAGGGTGAGACCTACAGGGCTGTGTGGGAGTAGAAGGAGGGCCAGGGCAATGTAGTCCTATCTCCCCTGCCCTGAAACCTCGCATCCAAACCTCCCATCACTGAGAGGTTAGCCACCCTGGGGTATAGTTGGGGGAGTAGAAGTCACTTCCCCCATAACTAATTTTCCCATTTAAAAAAAATTTATTACTTTTTAAACAAGTAATATACCTACATTATATTGCAGAAATTTAGATGTTACAGATAATACTAGGGTCTCCTTTTATCACTTCTGTTCCCCATCCGAGGCCCCCTCCAAAGGTAATCCTTTTAAGATTGAGATGTATTCTTCCAGACATTTTTACTTGTGCATCTATAGAAATACTTATAGAAATAGAGAGGCTTTTGGCCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGCGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCCGGCGTGGTGGTGGGTCCCTGTAGTCCCAGCTACTCAAGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCAAGATAGCACCACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCATCTCAAAATAAATAAATAAATAAACAAACAAATAAATAAATAAATAAATAGGCTTTTTTCCACCTAAAATGGTATTCAAGCATTTAATTGAAGTATAAAACATATACAGAAGAATGTACAAGTAATTACCATAAGTAACAGCTAAGAAGCATTTTCACAAATTGAATACACTGGTTTAGTCAGCATCCAAGTCAAGAATCAGAAATTTTCCAGCCCCCCATCCCCAGCAAGCCCTGTTTTGTTCCATTTCAGTCTCTGCCCACACCCACTAAGGTTAACTACTATTCTAACTTCTAACAGCATAAAATAGTTTCATCTGTTTCTGTGCTTCATATGAATAGAACCTTACAGAATAAACTGCTTTGTGTCCATCTTTTCCTCACCATGTTTGTGACTTTAAGCTATGTTGGATGTCATGGCTTTTTAAACTCGGAGATTTGCTTTGGCAAACTTTCTGATACATATGGATCTACTTTGATCTTTTTAATAACTACGTAATATTCTAAAGTTTAAATATAGACTACATTTTACCTAGTTTCTTACTGATGGACTTTGTGATTGTATAGAATGTATGCAGACTGTTTCTCAAGAGTAGATGAGAAAATAACATCTGGATCATAAGCACGTATGTTATTGGTTTTAATAGATACTGAAAAATGGTTATACCATTTTATTTATTTATTTTTTGAGGCTACCCAAGTGATGGCAGTGAGGGTAGAAGCTGGGTGATATGGCAGTTGGCTCTCTGCGGTAATCTGTGAACATCCTTCCTACCTCCACACCCCAACCCCTGCTGAAATGCTAGGTTACAGAGTTTAGAAATAGCCTGGTTTCATGAAGGGTGCGCGGACATGGGAAGGGCTCACTTCCACTGGCTTAATGTATGAGGAGACCTGGAGATAACCTCTCGTGCCTGTGTCTCCTACCTTGTGCCTGAGTCTCCTGGGTACTGTGCTGATGAGGGAGGTAGCACTGGACTAGCCAGGATGTGCTGGTCTGGGTTTGGGATGGAAGTGCATATGTATGTTCACTTACCAGGCTCTATGCTGCGTGCAGACTCTGAAGAGACTAAGGCACTTGTTGAAGGTCGCTGAAGAGCTCTGGGTAACAGCACTACTGGCAAGCCCACTGCATTTGACAAAATCTGAGTGTGACAAATTCTGATTTCATATGTCGTGATAATGACGTTGGGGGTATTGGAGAAACCTGTAGAAAAACTATTTTAGAGTCTGGTGAGAAGCTTTTCATGACAGAAGGAGCTCTGGTGAGTTTCTGTTCCTGGCTGAGTGTATGCCTTGTTCCCTGTATAAGTCTCTGCCACAGTTGGCAGAAGACTTAGGGAAGATAGTTTGGGATGACTTGTTCACCAAAGCTGTTGCTTCCCAGTCTTGTTCTTCAGCTTGCTGCCTACTCTTTACTGTTATGTTGGGATTCTTTATGTAAGTCCACTTGTCAGGCCCTGCTAATGGATTTAGATGACACTCAAGTTTGTGGAACTGTTTCTAGTACAAATGATACTCCAATCAGCTTTCCCACATTATACATATGATGTGCGCTGTTTGTGTCTTAGTCTGCTCAGGTTGCCATAATGGAATACCATAGATTGGGTGGCTTAAACAACTGAAATTTCTTTTCTTACAATTCTGGGGACTGGAAGTTAAAGATGAAGGTGCTGTCAGGATTCGTTTCCAGTGATTCTTCTCTCTTGGGTTGGCATATGGTAGCCTTCTTGCTATGTACTTTTTGCTGTGTGTATCCACTCCAGGTGTCTCTTCTTATAAAGATACCAGTCCTGTTGGACTGGAGGCCCACCTTTATCACCTCATTTAGCCTTAATTACCTCCTTAAAGTCCTTATCTGTAAATATATTAATGGCAAAACCTGCAATTACTTTTGCACCAACCCAATAGTCACATTGGAGGTTAGGGCCTCAACCTATGAATTTTGGTGGGACTCAGTTCAGTCTATGACTGTCTGAAACAATAAAGTTTGGTTGAAAGTGAATTCTGTTTTCCTCTTGAGTGACATTTTGGAATGGAAGTTAATTTTTTCAGGGCTTTGCCCTGGTGTCTCTGTTGTTCTTGCTTAATACTGCCCATGGACAATCTTGTCTACACTGGTGGGCTTAATTTCCGTGTATGTGTGCAGGTTCCCTTGCCTTTGGGCATGTTACGATCCTGAAAATATGTCTAAAAGCTGGGTGAAAAGTAGATATGGAGATGTACTTTTCTGATAATCAGGACCAAATATCTTTCTAAAGGTAACTGGAGAAACTAGAAAAAATAAAACTTCTCTGGTTGAAGGCATTGTATATCTAAGAAGATACTGAAGAACTACCAGGCCAGTATCTGCATGAGAACAAAGGCCTAGGGTGATGATTTTGGTATTTGAGTCTGTTTTTAGTCATAGGGGCAACTGAGAGGCTGCATTTGATAGCTTTGTGGGGCTAGGAAGACAGGAATTGGAGTTCTAAGCAAAGGGTGGGCAGAGTCAATCACTTATTTGGGATTGAGATCCCAAAGATATAGAAGTTAGGGGGACCAAAATGTAGACAAACCCTAAAGTTAGATTGAAATATTCTGGGCTGCTGGGTTTGGTGGTGCACACCTGTAATCCCAGCTACTTAGGAGACTGAGGCGGGGAGGATCAGTTGAGCCCAGGAGTTCAAGACCAGCCTGGACAATATAGGAAGACCCCATCTCCAAAACAGAAAATATATTCTGGGATTAATGGTACCTTTAGACATGTTAATTCTTTCTAGAGGATTTATGTCATCCTAGGCCTCGAATTATCTCTATAATTTTGCAAATACAATGACTGGCTGGTAATTTTAAGTAAACAGCCAGCAGAAACATCACAGTTGAAACCAACCTGGATGACCTCCAGGTTGGAGTTGCCATATACATATTTAAAAATAGAAGTGTTCGGGCTGGGCGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACGAGGACAGGAGTTCAAGACCAACCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAATTAGCTGGGTGTGGTGGCAGGCACCTGTAATCCCAGCTACTTGGGGGGCTGAGGCAGGGAATTGCTTGAATCTGGGAGGCAGAGGTTGCAGTGAGCTGAAATCGCACCACTGCCCTCCAGCCTGGGTGACAGAATGAGATTCCATCTCAAAAAAAAAAAAAAAAAAAAATAGCAGTGTTCACTGTGGTCAAGGAAATGAGAGTGGGAATTTCAGCAGATAGCTGAAAACTATAAACCAAAGGAAAAATCTCTTAAAGACTTGTTTTACGTAATAACAGAAATTAATAAATCAATGAATGCTTTTATCAGGGGATTAGGTGAAACTGTATAGAGCATTAGTGAATTGGATGATAGATCAGAAGAAGATATAAACTGAAGCATGGACAGGCAGAAAGATGGATAATAACAGAATAAAGAGAAACGCATAGAGGATGAAATGAGAAGGTCTAAGAGTCATGAAATCACAGCCACAGAAGTAAAGGAGAGAGAATGAGGCAGAAAAGTTAATAGCTGAGAACTTTCTAAAATTAATTAAAGACATCAAGCCACAGATTCAAGAAGTCCTGTGAATCCCAGGTAAGACAATAAATTTGAAAAATCCACATCTATTTCCATCACAGTAAAAATTCCAGAAAACAAAGACAGAATGTTGAAAGCAGCTAGAGAAAAAAGGCATTACTATCAAAAGAGCTGTAGTTATACTGACAGCTAACTTCTCAATAGAAACAGTGGAAGCCAGAAGATAATAGAATGATAGCTTTAAGTGCTGAAAGAAATAGTTGTCAGCCTAAAATTCTGTATCAAGTGAAGCTGTTGTTCCAGAATGAAGTCATCATCATGTTAAGTGAAATAAGCCAGACATGGAAGGACAAATAACCACATTATCTCACTTATATGTGGAATCTAAAAAGGTTGATCTCATAGAAATAGAGCGTAGAATAGTGGTTACCAGAGGCTAAGGAGGTAGGTAGGAGGTCAGATGGGGAGAGGGTGGTCAAAGGGTACAAAATTACATTTAAAGGAAAAAATTCTGGTCTGTTGCACCGTAGGGTGCTTGTAGTTAGCAAGAATGTATGGTATATTTCAAAATAGCCAGAAGAGAGGATTTTGAATGTTCCTACCACAAAGAAATGATAAATGGTAATGGATTTGTTAATTACCCTGATTTGATCATTACGCAGTGTATATATGTATCAAAACGTATTCTACCCCATAAATATGTACAGTTATTACGTGTCAATTTTTAAACCAAAACTTCTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTATCACCCAGGCTGGAGTGCAGTGGGGCCATCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGTGATTGTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACACGCCACCAAGCCTGGCTAATTTTTGTATTTTTTAGTAGAGACAGAGTTTCACCATGTTGGTCAGGCTGGTCTTGAACTCCTGACCTCGTGATCCACCTCCCTCAGCCTCCCAAAGTGCTGGGATTATAGGCATGAGCCACCACGCCCGGCCTACAAAACTTCTTAAAAAAGAATGAACATGTCAAGGAATGTGTTCTTCAGGCAGAAGGAAAATAAATCCAGATGGAATGTCAGAGATGAAGAGAGGAATGAAGAGCAATGAAAATAATAAATATTCGGGCATTTATTGTGAGAATGTGTTACTGAGTTTGAAATACCACAAAAGAAAATGCTTGGCAACAATGCTATCTGTGAGAGTGGAGTGAAAATCAATTTAAATTGTTCTAAAGATTCTTACAATGTCCAGGAAGAGAGTGGAACTACCAAATAATACTAAATTTTGATAAGGCATGCTATCATCTCTAGGGTAACCAAAGGATAGATTATAATTTTCAAGCTAAAAAAGAGACAAATGGGCTGGGTGCGGTGGCTCACGCCTGTAATCCAAACACTTCGGGAGGCTGAGGTGGGCGGATAACCTGAGGTGGGTTGTTCAAGACCAGCCTGACCAACATGGAGAAACCCCATCTCTCCTAAAAATACAAAATTAGCTAGGCATGGTGGCGCATGCCTGTAATCCCAGGAGGGAGGCTGAGGCAGGAGAATCACTCGAACATGGGAGGCGGAAGTTTCGGTGAGCTGAGATTGCCCCATTGCACTCCCGCCTGGGCAACAAGAGCGAAACTCTGTCTCAAAAAAAAAAAAAAGGCAGACAAATGGGTTGAGTGCAGTGGCTCATGCCTGTAATCCCAGCACTTTGGTGGTTCAAGTGGGGAGGATCACTGGAGCCCAGAGTTTGAGACCATCTTAGGCAACGTAGTGAGACCCCATCTCTACAAAAAAAAAAAAATTAGCCGAGTGTGGTGGCATTGCACCTGTAAGTCCGAGCTACTTGGGAGGCTGAAGTGGGAGGATTGTTTGAGCTCAGGAGTTTGAGGCTGCAGTGAGCTGTGATTGAGTCACTGTACTCCAGCCTAGGTCACAGAGCAAGACCCTGTGTCCAAAAAAAAAAAAGGAGACATGGAATAATAGAGAATTCTTCAGTTGAGAAGAAAGCAATGAGAGACAAGGGAACATAGACCAAATGAGATAAATATAGCTAATATTTCTAATAAATATATGATGTTAAAATTATTATTATTTTTAAGACAGGGTCTTGCTCTGTCACCCAGGGTGGAGTGCAGCGGTGCAATCTCAGCTCACTGCAACCACTGCCCCTCTAGGCTTAAGTGATCTTCCCACCTCAGCCTTTGAAGTAGCTAGGACCACAGGTGCAAACCACCACAACTGGCTAATTTTTTGTATTTTTGGAAGAGATGGGGTCTCACCATGTTGCCCAGGCTTGTCTCGAACTCCTGAGTTCAAGCAGTCTGCCCGTGTCAGCCTCCCAAAGTGCTGGGATTATGGGCATGAGCCACCATGCGGGCCTGATGTAAGAATTCTTAATAAATAAGTAAGGATGGACCTGAATACTTACTAAAAGCTCTGAGGCCATGGGTGGAGTTGGCTTAATCTAGGGTGATCTGATTGGGCTGTTTTGGGAATTAGTTGGATTCCCCTGAGAAATATCTTCTGTTTTCTCTCTGGAGGGGGCAGGCTTGGATATCAACATCCTGGAAGTCAAGGGGGTTGAGAACTAGGGGTTCCTGTATTTGGTATATTGTTCTGTATTCCTCCTGTTTCAGTGTGATACCTGTGTCCTCAGATTTGCCTGCTCCTCTTTGTCGAAGAGGCTCTCTGTTCATTTTCTTTAGAAAATAAACATAATCTCCGCTGGGTTGGAGAGGGGCAACCATGATGAGTGGTGGTGGGATCTGAGGATCTGACTGTACCTTACTAACCAACTCTTCTGTCTTTAGACTCATTTTTACCCCATTCTTTCAAAGACATCTGGTGCCACAAATTCCTGAGTTTTGAAGGGTTCTGTGGGGGAAGTCACATTGCTTTTCTACTTTATCCAGAGCCAACTTAGGAGTCTGTGTGATCAGTTACCATGTGTGTAAGTGCTTTCCAGCCTTGAAATGTCATTTCTGTAGTTCTCTCCTGTTCTCTTTGTTCTTACAGGTTTATGCATTAAACTACTTTATTGCAGTTTTAGTGGGACTACAAGAGGGAGCAAAAAGGAAATGTTTGTGTATAATCCTTGACCTTTACCTGGAAGCTCTCCTTCCAGTGTTTTCCAGGAATGATGGGGCCTGGAAAAAGGCATGTATTTCAGAGCTGTGGGAGGATGGTGCCAGGGCCTTGTTTACAAAGTCCAAGTTGGAAGTGACTTGAGGTCACCTGGCTTGGTTCCTTGTTTCTAGGCGGGACTTCTGAAGGCAGATGGAGCTCCTCCTGTCACCTTGGAAGGTGCTCCTGTATTTACATTTCTGGCATTTGTAGTGAACAAAACAGTGGAAAATCCTCATGCAAAATACATAGAAATGCTGGAAAAAGTATAATAAACACCCTTTTAAAATGCATATACATTGCTGCATGTATAAGAAGTAAGGGAAAAACAAGAAGGAGCTGGAAACTAGAGCTGTATGCCTTCACTGACTGAAACTGCTGATTCCTTGGGGACTTTGCCTGTCTTTATAATTTAGAGATGTGGGTTTAAGTAGCAGTGTGGACAATAGGAGAGAAGATGTGGAATTGAGACTGAGGCCTTTGCATGGCTTCAGACTTCTGTTGTGTTATACCTTCAGTAAAAATGTGGGCCAGAAGAAACATGTCTTTGTTGACAAAGAGACTAAATAATGAAATTGTCTGAGACTGGGTAGGGTTGGGGTTGGGGTAGTTTCCCCGAGAATTTATAACCATAGGCCTATGCTCATGTGAGCTTGGCATTTATACCATCCTGTTCTCTGGTAAACTAAGTTGAGAAATTAAAGTGGTTCCAAATAGTTAATGTCCTAGGGAGATTGGCAGAAGGCAGAAATATAAGTTACCTTTGAAAGGTTGCCCCTTCAAACTTGGCCTCAAAGTAGTCCAACAGAAAAGGCCCCACTGAACATAAGCTCAGTATTCAAAATTCTAAAACCACATGAGGAAACAGTACCATGAATAAAGTCAGAAATAACAAATGTCAGAAGCAGACTTTCAAGAAGTTAAATTACAGAATTCTAAGAGAGATTTGGAAGTAGGCCAAAGTACAGAAGTATCAAAATTGACCAGGAAGTTTTTTTTTAATAGAACTTCTAGAAATGAAAAAATAGAATAATTGAATTTATAAATTGAGTAGAAGAACTAAACAACAGATTAGACATAGCTAAAGAGAGAATTCGTGAATTGGAAGTTGATCTTCAGGAATTACCTGTAATGGTGTTTAGACACAGAATTGGAAATTAGGAAAGGAGGGTTAAGAGACTGGGCAGAATAAGAAGGTCTAATATGCTTATAATAGGAATTTCAGAATCATAGAATTTGGAGATGCAATATTCAAGTTGATAATAGCCAAGAATTTGTCAGAATTGACAAAAAACACAAATCATTAGACTAAAGGCATAGTGAACCCCAAATAGTATAAATTTAAATATATACTTAGACACATACCTTGTAGTGAAACTGCCAAGAGAGAAAGCAGCCAGAAAGAAAAAAACAGAATATCTGCAAAGTTAAATTAATAGCAGACTTTTCAGCAACAGTAGTGGAAGCTAGAAAATAGTGGAATAATATTTTCAGAGAGCTGAGGTAAAATAACAATCTAAAATTTTATGTTCATCTAAATTGCCATTCAGGAAGAAAGACAAAACATTTTGAGAAAAGCAACAAAGGCTCCTCTGCCAAGAGATCTCTACTGAAATATTTTTTTTCAGTAAGGACAGTGATCTCAGAAAGAAAGGCAGAGATGCAGGGAGAGATGACTGTATGGATGCTTACAAAATATAGACACAAATAATGTCTGATTTGGGAGCTGGGTAGTAAGAACAGTGACACTAAATACGGAACACAAGCAATATGTTAAATTAGATGTACATTGGAAGAGTCATTAGAGTTTAAAATATTTAAGTTCCAATGAGGGATGGTAGAGATGTTGATTTAGGCTTTTAGTATAAGTGTACCCATTAAAGTTTATAGGCCTAGCTTACAACGGAATAGGAATGAGATGTATAACTTTAAAAGTGGCTAAAATAGGAAATTTTAAAAGATAATCCAAATAGAGGTAACGGTAGAAAAGAAACAAATTTAAACATACCCAGTAATCATATATATAAACATACCCAGAAATCATAAATGTAATGAGACCGAACTCTAATTAAAAGATGGTGTTAGATTGAATTGGGGGGAGGGAAGAGAGAAAGATTTTTTGTTTAAGTTAGAAAAGGTAATTTTCTCTAATACTAACACACGAAATGTCATATAGCTATGTTAACATCAGATAAAATGGACTTTTTGGCAAAGAGCATTCATTACAAATGAAGAGGGTTACTATATAGTAAGAAAAATTTTATTACCAAGAATATATAAAATAATTTCTGTAACTCAAAGGAAAAGTAATCCAGTAGAAAAATGAGAAAAGATACAAACAAACAGTTCTCAGAAGGAAATGTTAGTAATCACAAGAAGATGATCAGTCTCACAAGTAATCAGGGAAATGCAGATCCAAATTGTGTACCATTTCACACTCACCAGGTGAACCCCAGGTGGGGGCTGTCATCTGTTGGGAACTTGGATTGGCACATCCACTTTGGAGAACAGTTTAACAGTATTTAGTCAGTTGATCTTTAGACTCTATGACCTAGCCAAGAAACGCCCACACATGAGTGCACACACACACGCACACACACAAATGTAAAAAAGAAGTCATGATGGCATTGCTGAGATCAACAAACATAAATAACCTGAGTCCAGTAGGTGAGTGGATACTTAAAGTTATGTGAGGTTATAAGCTTCTGAAATAAATGCACTTCAGGGCTGCAGGAGAGGCAGCAGTATATAAAGAACATGCACTCTAGAGACAGGCTGCCTGGGGTTTGAAGCCTGATTTTGACACTTAATAAGTAACTTGGGTAGGTTACTTAATCTCTTTGTGCCTCAGTTTTTATAAAATGAGGACCTGCACAGGTTTATCGTGAGGATTAAATAAGTTACTCTTTGCAGAATGCTTAGAATAGGACCTGGGATGTAGTGTGAGCTGTATAAGTGTTAAATTAATGCATATCAACCTGGATGGCTTACAAATATATGGATGAAGGACAAAAAGCATATGTATTAGAGATTGTATTTGGTTGCTAGAAATAGTCAAGAGTTATTCTCTTGGGTAAAAGAAATGCAAAGACACAATGTTGGAATATTTTGGGTTTTTTTCTCCCCTATTGTACATGCCGCTCCACAGTGTGCATACACGTGTGTGCATGTGTCAGTGTCTTTATCTGTTATACACTCCAGCCTTCCTTCCTGGCCCCATCTGTCTCTTCAGGTTCCCTCCATCTCTACACCCCAGCTGCCCTTACTCTGCTGCTGGGGAGGTGGTGGAGATGCTGCTTTGTGGAGCTGGGGGCTGTGGAATCATAACATGGATAAGTCACTGCTCTTGGCCCTCCTTCGCTCTTATGGAGGGACCTGCTAGGGCTATAAAGGCAGCTGAGCAGACTCAGGGCTGCCTTTCGAGGGGTGCTGTCTGTGGGGAGAGCTGCCTTTCCTCTCTGGGCAGATGTGAAGGCTGGACACCAGAGGGAGAACACTGGCCCTCCTGAGATGTTCTTGCTTGTCTTCCTCTTGGGCATGGAGGCTTCTGGCAGGGTGTGCCTCAGTGTGCTGGCAGAAGCAGACCTAGATAGATGTAGTGGTGAGTGGCACTCCTTCTCACCTGGTGAGTGGCACTCCTTCTCACCACTACAGTGCCCACAAGGGTGGGGCTGGGCACCTGCTCCCTGGGGTAGGTGGCTGCCAAGGGGCCTCCAGGAGCCAACTGAGCAGTGGTTCTGCTGGCTGCTGGGGTCACAGTTCCTCTAGGAGACACTGGCTGGACTGGGGACACCCAAGTGCAGAGCTCAGGGACTCCAGGGGAGGTGGGCATGGACACTCCACCTCTGAACCATCTCCTCTTCTTTCTCTCCCCATTGCACTTTGAGCCCCTCACAGATGGGACCTTGGTGAGGTTTCTCCCTTTTCTCCTCAGGGCATAGTGGGTATGTCCAAGGCCTACTGGACTGAGCTGCTTCATAGGAGAAACGAACCTCCCAGTATTTGACCTCCCAGTGCGTGTCTTCGAGCATCCAAACTAGCCGGCTTAGGTTCTGCTACCAGGAATGTTGGTTCAGAGTGCAGTCTGCATGTACTGTGTGTGTGTATGTGCATGTACTGTGTGTTTGTGTGAGGGTCGGGGGTGGTGTATGTGGGAGTGGTCCTGCCAGGAGGGATGGTTTGGGGAGCACTGGGTACTTTCTCTCTACTGGCATTAGGCCCCTTGGAGCATAGGGACTGCCCCTTGGGGACACTGCCACTTTTATTTCAGCTTCCTTTGGAGGCCAGCAGTTGGTTTGGCTGTGACTCAGGGATGCAGCAAGCCCCTTGTCCTGGTGTCTGGGGGCCATGCTCACTTACCTCAGGGCTATGAAGCAGCAGGCCTAAGGGGGTACCATAAGCACCCGCATCTTGGGAGCATGGCTTCTCCTCCTGCCAGGTTAGGCGAGTGGGCTGGGGGTCAAGGGGAGCCTCCTGTGCATGGATGCCCTGGCTTCCTGGGTGTGGGTGGGAATCTGTATCTATTAAAAGGCAGAGGTGGCCTGTGGTTGGAGTATTGCCAGAGGCTATAAATAGCTGAGTGTGTGAAGAAGGAGAGTCTGGGGAAGAGAGAGGAATGGGGGAGGCCCCTGGGTCTCCAGGTGGCAGCAGAGCCCTGTGGTGAGGGAGGGGCATGGGCTCTGAACATAAAGCTCTTGTAGGCATGGTGTGACTTGATGGGCTGGGAGTCATACAGGGGACTTGTGTTATGAGGGATTGTCATAGGCAGTAGGGGATGGTTGTGGCTGTAATATAGCCAATGTGCCAGGCAGTGTTCTAACCACTCTTAAAGTGCATTAACTCAATTAGTTCCTACAACTACCCTAGCTGTGAAGTATTGGAGTAGGACTTGAAGTCTGGCCCGCTCACGGCTGCCATTTTTCGCTGGGTTGCCTGTAGGAGGATCTGGTCAGATGGGGGTCAGGTGACATCTTTTTGAAATGGAGTCTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCACGACCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTGTCCGCCGCCATGCCTGGCTCATTTTTGTATTTTTAGTAGAGACCAGGTTTCACCACATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCTGCCCGTCTCAGCCTCCCAAAGTGCTGGCATTACAGGCGTGAGCCACCGTGCCTGGCCCAGCTGACATCTTGAACCCTTGGGTCCTCTGAGATTTGGAACTCCCAGCCTCTTCACTTGGGTACTGCCCATGGTAGTGGCAAGTGGGTGGTCCCTGACTTATCAGTGGCCTGGAGAGAGGAGGTTACTCTGTTGGCCTCCCTTGTTTGGGCTCCTGCCTCAGCACAGAGGCTTGTTGCTTGTCTGAATGGAGATGGAAACTCTTTGAGGACCTAGGGCTTGGGCTGCAGGCTGAGGCCATCCTTGTTGTCCCCTCCTTTCGACATGTTGCTCTAGCCATGATACCTATACCCTTCTGTCCTTCTGTCTGTCCACCCATCCATCTATGATGTGTTTGGAATGATTCTGCCACTTAGGACGGCAAGGGTCCTGCCTTTGTCGGCTTTCCAGTCTTGTGGGGAAAGCCTGACATTTAGAAAGTAGTTGTCGAGTACATGTGTAATGTTTTATTTCTCATACAAGTGTTCATTGTGTTATTTCCTCTTGAGATTATTTTTGGTTATATTATTGGTACACTTTTTGGATGTCTGAAATAATCCTTTAAGCAACAACAGGCCATTAGTCAAGGGTGGTTAAGTTAGGTGGCAGGGGAAGCACAAGGGCCAGTGGAAATAGAGAGTTTGCCTGGTCTCAGGGGAGAGGGAAGAGCCGAAATCAGAGGAAGGTGGGTAACCTTACGGCCAGAGGTGGTAACTTCCGACTTACGCTAAGCCTAGAAGCCAAACACATTCAAGGGTGTGACATTATGGTGTGGCTGCAGTGAGGGGAGGAAGGTAGGGGAGTGCCCAGCTTCCCTGTCTGCAGTGCAGCTTCATGGCTGGCCCCACAAGTCTCAGGTCTCCACGGACCCCCACTAGAACTGCTGCCGTGGATGCAGTGGGGCCCAGCCTGGGGAGAGGAGGCCCTGTGGCCTCTGGGCAGGGTGCTTCGAATAACCCAGTAATTGGGTGCTGCTGCAGGCAGACAGGGACAATGTAGGTGCAAGCCTCAGTCCTGGCCCCGGTGTGCTTGTTCAGCCTTTGGTCTACTACCCCCACCCCACCCTCTCAGGTTCTCCCTCTAAACCTTAAAGCCACATGCTTGATGAAGGGCCTGGCTGGGGAAGCCAGTGTGTACCCTTGTAAGCCTCTCTGTGGACCCTGAGGCCCTTCCTTTAGAAGAGGCTGAGTCCCAGCTGACTGACTGGTCAGGAGGCCATGCATTTTCCTTTCACAGGTGTCAGAGCCTAGGCCACCTGGTGCAGGATGACCAGAGCTGTGGCTGGGCACTGCCATTCTGATTGGGTGACATTTCGGACCCTTAGGTGCTACCTGGATCCTTGAGATTCGTTGCTTGCTCCTGCCCCTGGAAGAAGCATCCTGTCACTTCAGGGAGTTGCAGAAAGGGGTTGGGTTTGACAGGAGAATGGCCGCTCCAGTGGTGGGGGGCTTCTTTCACCTGACAGCCAGTCAGTATCCTTCTCTCTGGGGTATACCCTGGGAAATCAAGCTCTTTCCTCATGAAGGCCAACAGTAGGGGTGGAGATGAGCGTGAGGATGTCCTTAGGCTACGCTAGTGTTCAGGGTACTTTGCCCTCCCCCAGGGTCAGGGCAGGGTTCGTGTTCTTTCCTACTCCAGTCAGCCTTTCAGGCTGATGGCGAAGTAGGGCTCTTGGCTGCTGGTGGGCTGGCTGTCTGGTGGGATTGACTCTGACCCCTCCCTCCTTCCTGGGATGGGAATAGTGGTAGGAGAAGACCAGCCAGGAGTGGTGCCAGGTCACTGGCCTATGTGGGCCCAAAAAGTGTGGATAGGATGGCTGGATGCTTGGTGCAACTATCCTCTCGGGTGTCTGTGTGGGGTTCTGGCAGTGAGGTTGTAAATGCCACCACCTGCCTCCATTGTGGGCGGCCTATAATGGGGTGCTGGCAGAGCTCTCAGACAGAACCGAACCTCCTTTGGCATCTCCATACTCTTTCCTATGTCAGGGCTATGTGGTTCCTGCGGGTAGTGGGAGTAGACTGGGGCTGGGACTGGAGGTTGTTTTGTAGGGGATGGTGAGGAAGATGGATTTGGGGAATGTTTGAAATCAAGTTTGAAGGAAAGTGTTTGAATGGGCAGGTGGGGGTTGAAGTCGTTGTCCACCTGGATGGCACTTCCTGCAGCAGGTGGAAGGGGGTTCAGAAGTGATGGGGAGTGCCCTGGGGTCATCAGGAGCCTAGCCAGGAGAATGATCTGTGATTGCAGGTTAAGCCACCAGCTAGCTCTCCTCTGCCTGAGGCATGTATTCCCCTTGGTGACTCTGGGAGGCTTACCCTGTACACGCAGGCCTCATTCCTTAAGTTCTCCAGCCCTGCCGAGCACCAGGTGTGGTTGCTGGGTGTAGAAAGGACACTTACAGGGTCCTTTCCATTCCGTATGGGCAGGGAGTTGTGGAGGACCCACTGGCATGGTCTCCCTGGGGAACTGTTGTGAGAAGGGGGCTTGGGGGCAGAGACAGGAGCAGCAGGAAGCCACTCCCCTTTGTAGTTTTCCCAGGTGGTCCTTGAGATCTTTATCACAATCACCTGAGACAGACAGGGGTGATTAAAAGCACATATTCTGCCCCCATTCCCATTGGGATGGGTCTGGATTGGGCCTGGAAATACGTATTTGAATGAACACTGCTCCCCTTTCCCACACCTGCAACATACAGTGATTCCGATGTGCACTGGGGTTTTAAGGGGGCCTCTTCATCGGTTTCTGCTGCAGCAGGGAAGTAGCCCCCACCCCCACGCAGGAGCCTCAGGTGTTGGTGCCCTTTCTGTGCATCTGGACTCTGTCTGTCTGGCTGTTTATCCATCCTTCTGTGGCATTAGGTTTCCTGCCTCCTCCCTTTTGCTTAGGCCTAGGGGCAGCTGTGATGGGCTGCAGAATGAGGTGGGGGCTGGTGCCAGCTGGCACACGTAAATTAAGAGGTGTGGGACGGATGGGTGGCCTACGTCCAGGGGTGAGTGCAGGAGGTTGGTGACCCCAACCCACCACCCGGCCTCCCTCCCTCAGGGTGGCCTGGCACCCAGGACTGGGAGTAGGGGTTTGGGTGGTGGTCCCAGGGGCATGCTCAGTGGTTCTCTTTTCTCTGGGGCACAG
Seq C2 exon
GCTCTGGGCGTGGGGAGGCTGAGACACGGGAGTGCATCTACTACAACGCCAACTGGGAGCTGGAGCGCACCAACCAGAGCGGCCTGGAGCGCTGCGAAGGCGAGCAGGACAAGCGGCTGCACTGCTACGCCTCCTGGCGCAACAGCTCTGGCACCATCGAGCTCGTGAAGAAGGGCTGCTGGCTAGATGACTTCAACTGCTACGATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000114739-ACVR2B:NM_001106:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0106418=Activin_recp=PU(65.9=85.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)