HsaINT0003958 @ hg19
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136293754-136295221:+
Coord C1 exon
chr9:136293754-136293891
Coord A exon
chr9:136293892-136295058
Coord C2 exon
chr9:136295059-136295221
Length
1167 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGCG
5' ss Score
7.38
3' ss Seq
TGAGCCGGGCCTTGTCGCAGCGC
3' ss Score
4.22
Exon sequences
Seq C1 exon
CTTCGGCCTGGAGCACGACGGCGCGCCCGGCAGCGGCTGCGGCCCCAGCGGACACGTGATGGCTTCGGACGGCGCCGCGCCCCGCGCCGGCCTCGCCTGGTCCCCCTGCAGCCGCCGGCAGCTGCTGAGCCTGCTCAG
Seq A exon
GTAGCGGCCGCCCCGTGGGAGGGGCGCGCGAGCCTCCAGCCAGCCCGCTGGGCCGCCAGCGCCACCTCTCTCTACGTCCGTCCCCACTCCGCATTCAGCCCTCCTTCCTGTCCCACCCCTCCGTCCAACCCACCCCTCCGTCCAACCCCGCGCCCACCGCTCCGTCCGTGGAGGGGCGGGCGCGCGAGCCTCCAGCCAGCCCGCTGGGCCGCCCGCGCCACCCCTCCCTACGTCCGTCCCCACCTCTCCCTACGTCCGTCCCCACTCCGCATTCAGCCCTCCTTCCTGTCCTACCTCTCCATCCTGACCCACTCCTCCGTCCAACCCCGCGCCCACAGCTCCGTCCCATCCCGCTGCGCCCACTCCTGCGCCCACCCCTCCGTCCCAACCCCTGCACCCACCCCCCCGTCCCACCCACCTGCCCCACCCCCTGCACCTCCCCCCGTGCTGTCCCACTCTGCGGCCACCCTTCTGTCCAACCCCTGCGCCCACCGCTCCGTTCCACCCCCTCCCTGCGCCCACCCCTGCGTCCTCCCTCGCCCCCTTGCGCCCACACTTTCGTTCCAGCCAATCTGGGCACGCACCCCTCCGTCCATCCCCATCCCGCCCCTTGACTCCACATACACTCCCTGGTTCTCTCCCACTTGCCTACACCCACCCCTGCATCCTACCCTCCTCCATCCACCCCTCCATCTCAGCCCCCTGCACCCACCCCGTTCCTGGGCCCACCCTGTTCCTGCACCCACCCCCTCACTTCACCCCCTTACCCTTCGTCTGCCTCCACCCGCCCCTACCCCTCCGTCCACTCTCCACGCTCCATCAGTCCCACACCCCTATCTCCCCCACCCGCGTACATGTATCCCTGCGTCCCCTTCCCGCCGACCGCACCGCTCCCGGGCCTAACCTGCATCTGCTCCATCCCACTCAGACCCGTCCCTCCGTCGCCGCTCCCTCTGCTGGCCACCCACCTCTGCGCCGGCAGGAGCCTTAGTCTTGGTCCCAGCCAAGAGCCGGCTCCTGGTGGGGGGCGCGGGCCGAGAACTCCTGTTCCCACTCACAAAAGGCCACGCTTCCAAACGCTTCCATCCTCGTGCCCACTCCTCCGTCCCGCCTCCTCCCGGTGTACACCCCGGGACTGAGCCGGGCCTGAGCCGGGCCTTGTCGCAG
Seq C2 exon
CGCAGGACGGGCGCGCTGCGTGTGGGACCCGCCGCGGCCTCAACCCGGGTCCGCGGGGCACCCGCCGGATGCGCAGCCTGGCCTCTACTACAGCGCCAACGAGCAGTGCCGCGTGGCCTTCGGCCCCAAGGCTGTCGCCTGCACCTTCGCCAGGGAGCACCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-ADAMTS13:NM_139027:7
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.221 A=NA C2=0.283
Domain overlap (PFAM):
C1:
PF0142114=Reprolysin=FE(22.3=100)
A:
NA
C2:
PF0142114=Reprolysin=PD(5.3=20.0)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCGGCCTGGAGCACGA
R:
AGGTGCTCCCTGGCGAAG
Band lengths:
300-1467
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)