HsaINT0003970 @ hg19
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136290649-136291182:+
Coord C1 exon
chr9:136290649-136290732
Coord A exon
chr9:136290733-136291057
Coord C2 exon
chr9:136291058-136291182
Length
325 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGC
5' ss Score
8.99
3' ss Seq
GCTTTGCTGTGGGTCCGCAGGGT
3' ss Score
8.79
Exon sequences
Seq C1 exon
GGGGCAGAACTGCTTCGGGACCCGTCCCTGGGGGCTCAGTTTCGGGTGCACCTGGTGAAGATGGTCATTCTGACAGAGCCTGAG
Seq A exon
GTAGGCATGGAGCTGGAACTCAGCACACCATACAGAGCGGGAAGCCCAAGTCATCGCATCTCCATCCTCTTTAACCTCTTGTCCCGGATGCCCCAAGCAGCATGGATCACAGAATGCATTCAGCCAGACAGACCAGCTGCCCTCCCAGCTCTACCCAGCACTCAGCACAGGCTGCCTGACTACTTCTCTGAGCCTCAGTTGTCTCATCCCTAACACGGGCTAGTCATAGGGTTGTTAGGAGGACTAACTGGGAAACAAACCGACCGCAGTCAGCACCGTGCCTGGTTGGGGTGTCCTAAATGCAGGCTTTGCTGTGGGTCCGCAG
Seq C2 exon
GGTGCCCCAAATATCACAGCCAACCTCACCTCGTCCCTGCTGAGCGTCTGTGGGTGGAGCCAGACCATCAACCCTGAGGACGACACGGATCCTGGCCATGCTGACCTGGTCCTCTATATCACTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-ADAMTS13:NR_024514:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.111
Domain overlap (PFAM):
C1:
PF135821=Reprolysin_3=PU(20.7=89.3)
A:
NA
C2:
PF135821=Reprolysin_3=FE(33.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGAACTGCTTCGGGACCC
R:
TGATATAGAGGACCAGGTCAGCA
Band lengths:
201-526
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)