HsaINT0003971 @ hg19
Intron Retention
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136291058-136291465:+
Coord C1 exon
chr9:136291058-136291182
Coord A exon
chr9:136291183-136291318
Coord C2 exon
chr9:136291319-136291465
Length
136 bp
Sequences
Splice sites
5' ss Seq
TAGGTAGCC
5' ss Score
3.97
3' ss Seq
GACTGTTTTCTCTCACCGAGGTT
3' ss Score
-0.95
Exon sequences
Seq C1 exon
GGTGCCCCAAATATCACAGCCAACCTCACCTCGTCCCTGCTGAGCGTCTGTGGGTGGAGCCAGACCATCAACCCTGAGGACGACACGGATCCTGGCCATGCTGACCTGGTCCTCTATATCACTAG
Seq A exon
GTAGCCGAGCTTTCTGATGGGTGCTGGCCAGCCAGCCTGGGAAGGCTGCTCCCTCAGCCTCCTGCCCTCTGCAAAGGTGACCCCAGGGCAGGCACGTGCCTTGGCACCACCCAAGTGACTGTTTTCTCTCACCGAG
Seq C2 exon
GTTTGACCTGGAGTTGCCTGATGGTAACCGGCAGGTGCGGGGCGTCACCCAGCTGGGCGGTGCCTGCTCCCCAACCTGGAGCTGCCTCATTACCGAGGACACTGGCTTCGACCTGGGAGTCACCATTGCCCATGAGATTGGGCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323-ADAMTS13:NR_024514:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.111 A=NA C2=0.037
Domain overlap (PFAM):
C1:
PF135821=Reprolysin_3=FE(33.9=100)
A:
NA
C2:
PF135821=Reprolysin_3=FE(40.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGCCCCAAATATCACAGCCA
R:
AATGGTGACTCCCAGGTCGAA
Band lengths:
251-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)