HsaINT0004370 @ hg19
Intron Retention
Gene
ENSG00000185761 | ADAMTSL5
Description
ADAMTS-like 5 [Source:HGNC Symbol;Acc:27912]
Coordinates
chr19:1508442-1510257:-
Coord C1 exon
chr19:1510149-1510257
Coord A exon
chr19:1508570-1510148
Coord C2 exon
chr19:1508442-1508569
Length
1579 bp
Sequences
Splice sites
5' ss Seq
GGGGTGAGT
5' ss Score
7.93
3' ss Seq
CCGACTCCTCCTGCCCTCAGCGC
3' ss Score
8.97
Exon sequences
Seq C1 exon
GACTGCCCCCCAGGGGCTGTGCCCTTCCGAGACCTACAGTGTGCCCTGTACAATGGCCGCCCTGTCCTGGGCACCCAGAAGACCTACCAGTGGGTGCCCTTCCATGGGG
Seq A exon
GTGAGTAGTCTGGTCTCCTGTGGTCAGAATTGGTCCAGAGCGAACAACTCATTAGTCTCAGGGAGAGGGTCTTGGAGGGTTGCAAAGAGAAGAGGGTATTAGTGCTAGGGCTTTGAAGGATATGTAGGAGTTAGTGAAACAGAAACAGCATATGTTAGGCGTGAAACAGGGGCAGAGGGAAGCAGGGTTCATTCTGCACAGGGCTGAACACCCAACTAAGGATTGACTTAGAGCTGTATCCAGAGGCCAACACTTCTCAAACTTATCCCAGTAGCAGGAAATGTTGCTGCATTGAGCTGAAAATAGCGAGTTATATAACTACGTGCCCGGGTCAGTGCGCCTCCAGATTTCAGGGAGACAGGCAGCTTCACACGCCATGGGGAAGGCAGACACAGATATAAGAAAAGCCTAGAATGGACAAAGTGCCATCCATCAACCTCATTTCCTTCCTTCCTTCCCTTTCTTCCTTCCCTTCCTTCCCTTTCTCCCTTCCCTTCCTTCCTCCCTCCCTCCCTCCCTCCCTCCCTTCCTTCCTTCCATCAATCTGAGAATTGGAGGAAACCTGCTGTGATCCCACCCCCGCAGAGGCCCACTAGGGCCAGCCCAGGATCCGTTCCAGGCAGGGTCCACCAGCCAGGCTCAGGGAAATGGGAGCCAGAAGGAGCTGGAGAAGGAGGAGTGGAGATCAGGGCTGTCGGCCTTTGTGTTTGATCAGACAGCTCATTTTGCCCCACTTCCAGGCAGAAGGGGAAACTGAGGCCCAGGGAGGACCAGCGACACAGCTCAGTTGTGCGGGACTCAGTCCAGTCAGTACTGGACAAACACTTCATTGGGTACTTGCTGGTGCCTGGGCCAGATGCTCAGATCTTCTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTACAGCCTCCACCTCCCTGGTTCAAGCGATTCTCCTGCCTCAGCCTCCGGAGTAGCTGGGATTACAGGCTCCCACCACCAAGCCTGGCTAAATTTTTATTGTTGTATTTTTGGTAGAGACGGGGGGGTCTCGCCATGTTGCCCAGGCTGGTCTTGAACTCCTGGCCTCAGGAGATCTGCCCACCTCAGCCTCCCAATGTGCTGGGATTACAGGCATGAGACACCACACCTGGCCTTTTTTAAGGCCATCCATCTGCACACTGATTGAATTCTTGCTTCTGTATCCTAGAGCTTGGAACAGTGTCTGGAAAACAGTAGGTGTTCAGTGGAATGAAGAATGAGTAATGGTGTTAAAAATGAATAATATGTAAGGACTCCTAATATAAAGACAATGAATGAATGAATGAATGAATGAATGCAGCCCCAGGATACTTGCCTGCGAGTCCCAGGTTGCTGGACGCAGAGCACCTACGGTCCAGTCCTGGCTCTGCCTCAGCCTCGATGTGTGGCTTTGGCCAAATCTCTGGGCTTCATCTGCCCAAAGTGATGGTTGCCTGATGAAGCTTGGTAGAGGGGGACTGGAGCTCGAACAGGGGTCCCCGGCCCACCGACTCCTCCTGCCCTCAG
Seq C2 exon
CGCCCAACCAGTGCGACCTCAACTGCCTGGCTGAGGGGCACGCCTTCTACCACAGCTTCGGCCGCGTCCTGGACGGCACCGCCTGCAGCCCGGGTGCCCAGGGGGTCTGCGTGGCTGGCCGCTGCCTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185761-ADAMTSL5:NM_213604:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0009014=TSP_1=PD(2.1=2.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)