HsaINT0007979 @ hg19
Intron Retention
Gene
ENSG00000091879 | ANGPT2
Description
angiopoietin 2 [Source:HGNC Symbol;Acc:485]
Coordinates
chr8:6377385-6378931:-
Coord C1 exon
chr8:6378699-6378931
Coord A exon
chr8:6377516-6378698
Coord C2 exon
chr8:6377385-6377515
Length
1183 bp
Sequences
Splice sites
5' ss Seq
ACTGTAAGT
5' ss Score
8.59
3' ss Seq
GCCTTACTATTTTTTAAAAGCAG
3' ss Score
4.58
Exon sequences
Seq C1 exon
TTTCCTAGAAAAGAAGGTGCTAGCTATGGAAGACAAGCACATCATCCAACTACAGTCAATAAAAGAAGAGAAAGATCAGCTACAGGTGTTAGTATCCAAGCAAAATTCCATCATTGAAGAACTAGAAAAAAAAATAGTGACTGCCACGGTGAATAATTCAGTTCTTCAGAAGCAGCAACATGATCTCATGGAGACAGTTAATAACTTACTGACTATGATGTCCACATCAAACT
Seq A exon
GTAAGTTTACATATCATGCTTTCTTCAGCGTTAATAACCTTTAGTCAGTAAAACACTCAAAAGACTAAAAAATTCTCACCTTTCAGAAAAGGCGCTATTTCTCATATATTTCATATGAAATATCTACCAATTAAAATGAAGGAAGAAGAGAAGGGGAAATATATGTTATACTAATTATTATGAAGCAAACACCCCAAGCATACTTTTGATTCATGGCAGTAAAGAGCCTACTTTTAGTTAGTTCCATCATTAATTAGAAGGATGAGACTGGGCAAATTACTAAACCACAGCCGATATTCATTTATTTAGGTTTTACATGGGAAAAATAATATCAGACCCATGGGATGGCCATTAAGATTAAATGAGATAATACAATGGCACTTAAGAGATGCTAGTTCCCTTATCTTGCCAGGTTCTTAAGCACATTTTGCCTTCCTTATTATTGTTTCACTTTGCAGCGTCTCTTATATATTGGAGGGAAGGGCCAGGTGTGGTGGATCACGCCTCTAATTGCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACTTGAGGACAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCTTGGTGGTGGGCACCTGAAATCCCAGCTGCTTGGGAGGCTGAGGTAGGAGAATCACTTAAACCTGGGAGGAGGAGGATGCGGTAAGCTGAGATGTGTCACTGCACCCCACTATGTCCTCAGTGGGATAATGGCCTGAAGGGGCAGGCAATGGGGTCATGATACAGATAACAGTGTTTAGGGACATTCTTTTTAAATTCTTCCATACTAAGTTTACCCTATTCTGCTCAAGATGAAAGATCTTCAAAAGTAATAATTTAATTTATGTGATTGTGAAGTACTTTCATTACATGTAATTGATCATCAGCAAAGGAAGTTTGGATTATTTGAAGTATTTTAATTACATGGAATTAATGACCAAAAAGTAAGTATTAATCTTTTGAGAATTAAGAAGAAAACAGGCTGAAAGGAAACTTTCTAGAAAGGTTAAAAAAGTGGTACAGCCTTTTGCTTACTTAAGAATTCCAAAGTAATAAAACTCACCAAATGATTGGCTCTTGAAATAACAAGTCTTTGTCTTTTCATGAACTCCGTTTAAATGCCTTACTATTTTTTAAAAG
Seq C2 exon
CAGCTAAGGACCCCACTGTTGCTAAAGAAGAACAAATCAGCTTCAGAGACTGTGCTGAAGTATTCAAATCAGGACACACCACGAATGGCATCTACACGTTAACATTCCCTAATTCTACAGAAGAGATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091879-ANGPT2:NM_001147:4
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.070 A=NA C2=0.160
Domain overlap (PFAM):
C1:
PF0149614=V_ATPase_I=FE(42.9=100),PF0497710=DivIC=PD(38.0=24.1)
A:
NA
C2:
PF0149614=V_ATPase_I=PD(14.3=59.1),PF0014713=Fibrinogen_C=PU(14.0=68.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCCTAGAAAAGAAGGTGCTAGCT
R:
AGGGAATGTTAACGTGTAGATGCC
Band lengths:
342-1525
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)