HsaINT0007979 @ hg38
Intron Retention
Gene
ENSG00000091879 | ANGPT2
Description
angiopoietin 2 [Source:HGNC Symbol;Acc:HGNC:485]
Coordinates
chr8:6519864-6521410:-
Coord C1 exon
chr8:6521178-6521410
Coord A exon
chr8:6519995-6521177
Coord C2 exon
chr8:6519864-6519994
Length
1183 bp
Sequences
Splice sites
5' ss Seq
ACTGTAAGT
5' ss Score
8.59
3' ss Seq
GCCTTACTATTTTTTAAAAGCAG
3' ss Score
4.58
Exon sequences
Seq C1 exon
TTTCCTAGAAAAGAAGGTGCTAGCTATGGAAGACAAGCACATCATCCAACTACAGTCAATAAAAGAAGAGAAAGATCAGCTACAGGTGTTAGTATCCAAGCAAAATTCCATCATTGAAGAACTAGAAAAAAAAATAGTGACTGCCACGGTGAATAATTCAGTTCTTCAGAAGCAGCAACATGATCTCATGGAGACAGTTAATAACTTACTGACTATGATGTCCACATCAAACT
Seq A exon
GTAAGTTTACATATCATGCTTTCTTCAGCGTTAATAACCTTTAGTCAGTAAAACACTCAAAAGACTAAAAAATTCTCACCTTTCAGAAAAGGCGCTATTTCTCATATATTTCATATGAAATATCTACCAATTAAAATGAAGGAAGAAGAGAAGGGGAAATATATGTTATACTAATTATTATGAAGCAAACACCCCAAGCATACTTTTGATTCATGGCAGTAAAGAGCCTACTTTTAGTTAGTTCCATCATTAATTAGAAGGATGAGACTGGGCAAATTACTAAACCACAGCCGATATTCATTTATTTAGGTTTTACATGGGAAAAATAATATCAGACCCATGGGATGGCCATTAAGATTAAATGAGATAATACAATGGCACTTAAGAGATGCTAGTTCCCTTATCTTGCCAGGTTCTTAAGCACATTTTGCCTTCCTTATTATTGTTTCACTTTGCAGCGTCTCTTATATATTGGAGGGAAGGGCCAGGTGTGGTGGATCACGCCTCTAATTGCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACTTGAGGACAGGAGTTGGAGACCAGCGTGGCCAACATGGTGAAATCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCTTGGTGGTGGGCACCTGAAATCCCAGCTGCTTGGGAGGCTGAGGTAGGAGAATCACTTAAACCTGGGAGGAGGAGGATGCGGTAAGCTGAGATGTGTCACTGCACCCCACTATGTCCTCAGTGGGATAATGGCCTGAAGGGGCAGGCAATGGGGTCATGATACAGATAACAGTGTTTAGGGACATTCTTTTTAAATTCTTCCATACTAAGTTTACCCTATTCTGCTCAAGATGAAAGATCTTCAAAAGTAATAATTTAATTTATGTGATTGTGAAGTACTTTCATTACATGTAATTGATCATCAGCAAAGGAAGTTTGGATTATTTGAAGTATTTTAATTACATGGAATTAATGACCAAAAAGTAAGTATTAATCTTTTGAGAATTAAGAAGAAAACAGGCTGAAAGGAAACTTTCTAGAAAGGTTAAAAAAGTGGTACAGCCTTTTGCTTACTTAAGAATTCCAAAGTAATAAAACTCACCAAATGATTGGCTCTTGAAATAACAAGTCTTTGTCTTTTCATGAACTCCGTTTAAATGCCTTACTATTTTTTAAAAG
Seq C2 exon
CAGCTAAGGACCCCACTGTTGCTAAAGAAGAACAAATCAGCTTCAGAGACTGTGCTGAAGTATTCAAATCAGGACACACCACGAATGGCATCTACACGTTAACATTCCCTAATTCTACAGAAGAGATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091879:ENST00000325203:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.066 A=NA C2=0.160
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0014713=Fibrinogen_C=PU(14.0=68.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCCTAGAAAAGAAGGTGCTAGCT
R:
AGGGAATGTTAACGTGTAGATGCC
Band lengths:
342-1525
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development