HsaINT0008131 @ hg19
Intron Retention
Gene
ENSG00000151150 | ANK3
Description
ankyrin 3, node of Ranvier (ankyrin G) [Source:HGNC Symbol;Acc:494]
Coordinates
chr10:61819456-61823012:-
Coord C1 exon
chr10:61822869-61823012
Coord A exon
chr10:61819765-61822868
Coord C2 exon
chr10:61819456-61819764
Length
3104 bp
Sequences
Splice sites
5' ss Seq
ATGGTAATC
5' ss Score
4.14
3' ss Seq
AAATGTACTGTCTTCCATAGGTT
3' ss Score
9.85
Exon sequences
Seq C1 exon
CTGATGCCTTAACTTCGGTCTTGACAAAAATTAATCGAATAGATATAGTGACACTGCTAGAAGGACCAATATTTGATTATGGAAATATTTCAGGCACCAGAAGTTTTGCAGATGAGAACAATGTTTTCCATGACCCTGTTGATG
Seq A exon
GTAATCGAATTTAGTGTTCATATTTATTTAATCATTTGATAAAATTTGAAAGTGCAGTCAGACAAGGCAGTCACTTAAAAGCAACTAAACTGTGATTTGCTTGACTTAGTTTCTCATTTTCTCTGCCAGAGTCTGCAAATAAACACTCTGATATCAGAGCAAACTTGGTAAATACCTCTGTTTATATACAATATAAATATACAATATAAATCATGACGTATGAACGCCTAAGGTATCTGAAAGAGTTGGTATTTCTAATATTTCATAAAAGTTAAATATCTAGAGAATGCATTGCTTTTGTCACTTTTAATTTTTATATTAACCCTCCTAAACTAGTTACCTCTTTTATTCGTATATAGGTAAAACAAACGATGAGCCATTTTTATCAAATAAGCAAGGTATTGAGTAAAGTGTAAGCATATAGTATACAAATTGTAAGGTAAAATGGCAATTTACTGTGTGGCACCAGGTATTTAAATGTGCACTGAAAAAATTTAATGTATCATTCAAGTATGTGCTTTAGTTATTTAGCGTTCGTTGTTATTTTAACTTCATGAATATGCTGCCATTTATTCTTTGGAAAAACTGCTTGATCTATTGTATATCAAAGGCAGCATAATTTCTAATTCAGTCGGCATACATGTTACTAACAACAATTCCTCTTTCACATTAGCTTAATTTATATAATGATCTTGTCATTTTTTCCTCATTATGTAAATTGTGCTTTCTTCACTGAAATATTAAGAAAAACATAATAAATATCTTCCTATGTTTTTCAAAATAGTCCTGTCTTAGGCTCACAAATGAAAATTTATTCCTACAATGAATTTTTGTTCTGTTTTTGAGACGAAGTCTCGCTCTGTCGCCTAAGCTGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGCCATTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGCACCACCGTGCCCAGCAAATTTTTTGTATTTTTAGTAAAGATGGGGGTTTCACCACGTTGGCCAGGCTGGTCTCGAACTCTTGACCTCAAGTGATCCACCCACCTCTGCCTCCCAAAGTGCTGGAATTACAGGCATGAGCCACCCCACCCAGCCTCTATAATGAATTTTGAGTAGAAAATTTGATGATGGTGTGGAGGCAGGAATAAGAACTAAGGATATTTTTCTAGTATTCCATTTTTAAACTGGCAAAGTTAGATTAACAAGAGTCACAAACTTCTAATTAACTTCTAATTCTGCATATATTTTGTGGAAAAAATCTTAAAATTCTTAGAAAGTTCCTGCTTATTAAAAAGTTTAAGTCTGGCCAAGCACTGTCTGTCTCTTAAAAAAAAAAAAAGTTTAAGTCAACAAAAGATTTAAAGCATACTTGTTATACATGTAACAAACACAATGGGTAATGAAGTAAAAAGCGGTTCTTTTTAAGTTTATAAAGACCATAGAACCTTGGAAAAACGCTCCCTTTGAGGCCTTGTCTTATATGCAAGGCCATATATTAGTAACCACATGCTTTTTGCACTAGATAAATATAGATCATCTTATCAAATTTTAAATTATTGATAAGTTATAGTTTATACATTCTTCTAATATTCTTTATTGGAAAAAATAGTTGTTAAGTAACTCTAATAAAAAAGATCACCAGAACACAACAGAAGTAGTTGTGTTGAAAGCTTCATTTAATTTGAACATTTTAAAATTGGAATATCCTTAAAATACAGTCAAAAATGAAATGGCTTTTTGTTGCTGTATCTTAATATTTTTAAATTCCTTTTTCAAAATTTCTTAGGGAAATTTAGAAACATGTATATGAAGTAATTTCACTTAGGCAGATTATAAACCTCAGCTAATCTTAGCCAGCTTTTCAACAAGAGTCTGGTTTATAGATGACCATAACTGAAAAATGTTCACTTACCTATAGCAATTTGAGTTTACAACAGCAGCTAAGTTGGTATTTACCTGGGACTGATGGAAAAATTAGACTTTTATTTTGTAGACCAACAATTCAGAAACTGTGGTTTGTTGCTTTTTTCCTGTCTCTCCTCTTCGTTGAACTTTTATGAAACTTCCTTTCCTCACCATGACCAGACCATTGTTGACTTTTCTCTCTGCTGAGGCAGAAAAATGCTTCCATAGTCCATGCAGCAATGTTTAAAACAAGGGATTCGTTCCCCCCTCCCCTTTTGTGTAGGCTGGTTAATAAACTCTATGTTTCATAGCATTGTCGTGAATATTCAGAGTGCTCCCTGCGAATGGTTTTCCTACTATCTCTGTTGTGTATCATTTCTGTTTATTTGATTCGTGGTTCTGAGTGGACCCTACCACTGACTTCACCAAGACCTTCATGTACTCCACAACCCTTTCATCTTGGTCATATCTGTTTTTGTACAACACCCTAAAACTACATGGAGTCTTTTAAACTTGGTCTGTTTTTTCAATCCTTTTCTTAACATCGTTTAAAATTTTTTTCCCAGTGCCACTGCTCTAAAATCTAACAAACAATCATTTCTTTCCAAAGATTAAATCCGTTTTTCTGTGCTATAATTTCATGTGAAAGAAGAACTAGGTTGCTTTGCTCATATGTACAGTTCTTAAAATAAGTTGTAGGTAATTAATATAAAAGTTGTAGGTAATTAATGATAAAAATTGGTTTCTTGTGGCTTGCTGTATTCAGTCCACCACAGTATGAACTTCGCATGCTAAATATAGAAAGATAATAAGTATCTCATGTAATGACAACTAACTTTATATTGGTCTTTATATAAACTTAAATATATAAACTTTATATATTTAGTCTGCATACTTTGGATTAGTGTGCATATTTACTTATTGTATCATAATTTCCAAAACAGAAACAATTGATATCTTAATTAGTATTCTATTTTATTGGAGTTTGCACTAGGCTTTTTATTTCATTGTGTTACATTTAATTGAACTAAACCGATAAATTTATTGACATTAATCTGTAATTCATCATACATTTTTCATGCCTGATATAATTTTAGTCATTCCATGTGTTTTTGTTTGATGTATTCTAATTCATTCCAGTCAGTCCAAATGTACTGTCTTCCATAG
Seq C2 exon
GTTATCCTTCCCTTCAAGTGGAACTGGAAACCCCCACAGGGTTGCACTACACACCACCTACCCCTTTCCAGCAAGATGATTATTTTAGTGATATCTCTAGCATAGAATCTCCCCTTAGAACCCCTAGTAGACTGAGTGATGGGCTAGTGCCTTCCCAGGGGAACATAGAGCATTCCGCAGATGGACCTCCAGTCGTAACTGCAGAAGACGCTTCCTTAGAAGACAGCAAACTGGAAGACTCAGTGCCTTTAACAGAAATGCCTGAAGCAGTGGATGTAGATGAGAGCCAGTTGGAGAATGTATGTCTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151150-ANK3:NM_001149:16
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.145 A=NA C2=0.820
Domain overlap (PFAM):
C1:
PF0053117=Death=PD(27.4=46.9)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)