HsaINT0008168 @ hg19
Intron Retention
Gene
ENSG00000151150 | ANK3
Description
ankyrin 3, node of Ranvier (ankyrin G) [Source:HGNC Symbol;Acc:494]
Coordinates
chr10:62021617-62023778:-
Coord C1 exon
chr10:62023593-62023778
Coord A exon
chr10:62021716-62023592
Coord C2 exon
chr10:62021617-62021715
Length
1877 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
CTGCTATGTTTTCTTTACAGAGT
3' ss Score
10.17
Exon sequences
Seq C1 exon
GATGGCTTCACACCATTGGCAGTGGCTTTGCAACAAGGTCACGACCAAGTCGTTTCGCTCCTGCTAGAGAATGACACCAAAGGAAAAGTGCGTCTCCCAGCTCTTCATATCGCGGCCCGAAAAGACGACACGAAAGCCGCCGCCCTGCTGCTGCAGAATGACAACAATGCAGATGTGGAATCAAAG
Seq A exon
GTGAGGCACGAGGGACACGGGCCTGTCATGCAACTCTCCGGTGTTAGACACACAACCTTTAAGAGCACCCGGTCTCCCTCTTCGCAAGCTTATGCCATGCCTTTAACTTCATTGAAGGGAGGAACAATGTGTGTCTGAGCTAGCCACTGAAGGCACAGCCTCCCTTCACATGAGAAGTTGGGGGGTGAGGGGAATGCGGCCCTATGCGTGCTAAAAGGGAGGCCACCTCAGAAGAAATCAATTTCTATGCAGTGATCATTTCTTTCCTTTGAATATAGTTTTGGAATATATTCAACAGTTCAGCTCAAACATCAGGGCGAAAAATTACAAAATACTGAAGACAGTGTACACAAACAAACCTCTGGTTGATACCCAAGATGACAGGCCAGGCACTGAGCGTAGATCAGCTGCGGAAAGCATGCCAGCAGCAAGAGAGCCGCAGCCAAAAATTCCCATCGTCTTGACATGTGGTACCTGAAAGTCTCTGTGACGGAAATGTGACATTTGGACTAGGCCGTTGCGTAGCCCATCATTCAGTCTAGCTTTCTTTCTGTGCCTATTGTGCTTTCATCAGAGCTTCCATCCTCATTACTTAGCTGTCATGAGCTTTCTGCAATCCATATCACCAATAGTGAACTAACCGTTCATTTTTTCCTCCTCTTTGCTTCCAAATGTGTTAACCTAGATGGTGGTGAATAGAACAACAGAGGTATATATATATATGCATATACGTGTAGTCTATATCTGCATCATCATTTTCCCATGACTTAGTGCTGCTGCCTCATGTCTCTCCCTTCTTCTTTGCATCGCCTTCTGTAGGCTAGATACCTGCTTTATCCCCAATCCCTCCTCTCCCCAAAGGAGCATGTGCCAGATAAGATAGCAGTAGTTTGATTACCAGGGCTTTCTGCAGCTGAACCTGGTGTTTGAAAGAGATGAGGAATCCTTGACTCTTAAGGGTATTGCAATAGAGCTGTGTGAGATGAAGAGTCTGGACACTTTAGATGTTTATCAGCTATATCTAAAGCTGCAGACAACCCTGTCATTCTACTCATCCAGGACTCGTTTTTTAGGGTTGTGCATGACACTTACCCTCTGTGGTGTCAGCAAAAGGAAAGGTATTTCAGAATGGTGTCAATATGACCCACCCTTCTACAAGACTCAGTGAGATAGCTAGCATGGCTAAGAAGCTTGCTAACAAATTAGAAATGCATCTAGTTCCTATAAGGTTTCAATCTTTGGGGACTAAGTGAATCGCTGCATGTTTTAGCATTTTTTAAGGAAGTAAAATGACCTTGGTATGAACAATCCAAAAACATGTGTTATTGAATAGGCATTGGCTAACAAAGAGATTAACTTGTGGATTCTTCATGGAATACAATTGCCCATTATATAAAACCAACTTTGTGGTAGTACGTCTTCCCCCCAAAACTGCTTTTGTCATGAAAATTGGCATTTACTGTTCAGTAATATGAATCTATATCAAATATATAAACTAATTGAATTTTGAGTTTCAATGCACAATTCTATCGTCAGTAATAAAACAGCGGCACTAATCAAGCTATCAGCTATAAAGATTTTTCTCATCTCTATCTTAATTTCTTGAAATGTTGGCTTTTATATAGTTCTGTTATTGGATTACTAAAATTGCTCAGTCTCCACCCTTGGTTCCTCCCTGGCTATTCTTCTGCCTGTAAGTTTGGGGTTTATTAGAAACCCTGTGAGCAATTGGCACTGATCGAAACCTAGTACAGAATGGAACATAGACCTCAGCATATTTTGCTTCCTCATTTTTATTTGGGCAGGGTTATGATATTTGCCTGTCAGGCAGGGGGCTGGCAGGAATCAATTGAATGTCTGCTATGTTTTCTTTACAG
Seq C2 exon
AGTGGCTTCACTCCGCTCCACATAGCTGCTCACTATGGAAATATCAATGTAGCCACGTTGCTGTTAAACCGAGCGGCTGCTGTGGATTTCACCGCAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000151150-ANK3:NM_020987:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.016 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127962=Ank_2=PD(43.7=50.0),PF136501=Asp_protease_2=PD(68.2=93.5),PF127962=Ank_2=PU(29.8=45.2)
A:
NA
C2:
PF127962=Ank_2=PU(28.3=78.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGGCTTCACACCATTGGCA
R:
GTGAAATCCACAGCAGCCGC
Band lengths:
278-2155
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)