HsaINT0013360 @ hg38
Intron Retention
Gene
ENSG00000126522 | ASL
Description
argininosuccinate lyase [Source:HGNC Symbol;Acc:HGNC:746]
Coordinates
chr7:66089612-66092086:+
Coord C1 exon
chr7:66089612-66089695
Coord A exon
chr7:66089696-66092005
Coord C2 exon
chr7:66092006-66092086
Length
2310 bp
Sequences
Splice sites
5' ss Seq
CAGGCAAGA
5' ss Score
3.01
3' ss Seq
TCGCCCACCTGTGCCCCCAGATT
3' ss Score
8.09
Exon sequences
Seq C1 exon
GAGGACAAGGAAGCTGTGTTTGAAGTGTCAGACACTATGAGTGCCGTGCTCCAGGTGGCCACTGGCGTCATCTCTACGCTGCAG
Seq A exon
GCAAGACATCACCCCCCTGCTTCTCCTCCCCTAGGTCCCAGGCACTGGGGTGGGCATGCGGGGAGGGTGGCCTTGGGAGGAGGTGAGGTGGGGCTGGAGGACCTGGGGCAGGGAAGGAGAGGTGTGCTCGCTCCTGCTCCTGGGGAACAGGGAAAGGACAGAAACTGCTGCCATGCAGTGGAAGTAGATGAGACTCAGGGGGCCTGGGGCCTGTCAAATGGCCTGACCAGAACTCTTTAAAAAAAGAAAATCTAAACAAAAGGCCAGGTGCAGTGGCTCATGCCTGGAATCTCACACTTTGGGAGGCCGAGGCAGATGGAGCACTTGAGGTCAGGGGTTTGAGACCAGCCTGGCCAACATGGCGTAACCACGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGATGGCCCACACCTGTAATCCCAGCTACTCAGGAGGCGGAGGCAGAAGAATAGCTTGAACCCAGGAGATGGAAGTTGTAGTGAGCCAAGATCATGCCGCTGCACTCCAGCCTGGACCACAGAGTAAAACTCCATCTACAAATATATAAATTAAATTAAATTAAATTAAATATCTTTAAAAAACATTTTTTAGAGACAGGGTCACTCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCGGTCGTAGCTCACTGCAGCCTCAAACTCTTGGGCTCAAGTGATCTTCCCACCTCAGTCTCCAGAGTAGCTGGGACTACAAACATGCGCCACCACGCCTGGCTAATTTTTTTATTTTTTGTAGAGACAGGGTCTCCCTATGTTTCCCAGGCTGGTCTCAAATTCCTGGCCCCAAGCCATCCTCCCACCTTGGTCTCCCAAGGTGCTGGGATTATAGGCATGAGCCACTTTGCCTGGCTGATTTCTTTTAAAATCAATTATTATGGGAAATTTATGTATATAACAGCTAGAGAATGCATAATGAACCCTATGTACCGACACCCAGCTTCAATGATAATCAACTCACGGACATCCTGGCTCCAGCTGTCTTTACCCACAGCTCTCTCCCACTCCCTTACCCCCTTATTTTGAAGCAAATTCCCATCATCACATCATTTCATTCCTAAATAGTTCAGGATATGTCTTGAAATCAGTGTTTCTTGGCTGGGTGCAGAGCCTCATGCCTGTAATCCCATCAATTTGCGAGACTAAGGTGGGCAGATCACTCGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGCGAAACCCCGTCTTTACTAAAAATATAAAAATTAGCTGGGTGTGGTGGTACACGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGATGGAGACTGCAGTGAGCAGAGATCACGCCACTGCGCTCCAGCCTGTGTGACAGTGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGGCAGTGTTTCTGGAGGCTAGTCCCCCAACTAGCAGCACCAGCATCACCTCAGAAGTCCTGAGAAATGTGATGTGAGGCCCCACTCCAGATGGCTGAATCAGAGACTCTGGGGGTGCTCCCCAGCAATTTGTATTTTTCTTAGTAAATTCTCCAGTGGCTAGGCCTGGTGGCTCATGCTTGTAATCCCAGCACTTTGAGAAGCTGAGGCAGGAGAAGCGCTTGAGCCCAGGAGTTCAAAACCAGCCTGAGCAACATAGCGAGACCTTGTCTGTAAAATTAAAAAAATTAAATTAGCCAGTCGTGATGGCGTGTACCTGTGGTCCCAGCCACTTAGGAGACTGATGTGGGAGGATCCCTTGAGCCCAGGAGCTCAAGGATGCAGAGAGCCAGGATTGTGCCATTGCACTCCAACATGGGCGACCCTGTCTCAAAAAAGCCCAAAACAACAACAACAAATTAGCTAGGCACGGTGGTGTGCATGGCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCTGGAAGATCCCTTGAGTCCAGGCTGCAGAGGGCTATAATGGCCACTGCACTCCAGCCTGGACAACAGAGCAAGACCCTGTCTCCTAAAACAGAAAACAAATCCTCCAGGAACATCTGATGCATGCTGAAGATAAGGACTCTTTGAAAACATAAAGGCCAGTAAAACATACAGGCCAGTAAGTGTTCATAGCACATGTAAATATTATCGATAATTATGAGAAGATGGTTCAAGTTGAGAGTGAGACAGAGCCGAGTGGGTAAGAGAGTATCTGCCCAAGGCAGGGATGTCCTGGCAGAGGGGCAGGTCCTGGGCCTGGCAGCTTCAGATCCCAGGGTCCCCAGGGCTCACCACTCGCCCACCTGTGCCCCCAG
Seq C2 exon
ATTCACCAAGAGAACATGGGACAGGCTCTCAGCCCCGACATGCTGGCCACTGACCTTGCCTATTACCTGGTCCGCAAAGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126522:ENST00000304874:14
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.006 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF146981=ASL_C2=PU(20.0=51.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development