HsaINT0023655 @ hg19
Intron Retention
Gene
ENSG00000125730 | C3
Description
complement component 3 [Source:HGNC Symbol;Acc:1318]
Coordinates
chr19:6719222-6720662:-
Coord C1 exon
chr19:6720527-6720662
Coord A exon
chr19:6719415-6720526
Coord C2 exon
chr19:6719222-6719414
Length
1112 bp
Sequences
Splice sites
5' ss Seq
CATGTGAGT
5' ss Score
7.83
3' ss Seq
CCCGTGCCCCACTCCGACAGGTA
3' ss Score
9.54
Exon sequences
Seq C1 exon
CACTCCTCCCCATCCTCTCCCTCTGTCCCTCTGTCCCTCTGACCCTGCACTGTCCCAGCACCATGGGACCCACCTCAGGTCCCAGCCTGCTGCTCCTGCTACTAACCCACCTCCCCCTGGCTCTGGGGAGTCCCAT
Seq A exon
GTGAGTGGTTATGACTCTACCCACAAACAGGGCTGGTTCTGGGGTGGAAGCAGACATTTGGGGGTCCAGGTCCCTGTAGAATTCAGGGTGCATTTGGGTGTTTGTGGATTCAGGGGTTAGCAGGTTGGGAATGATTATATATATTTGGGCTGCCTGTGAGTTTGGGTGTTTGTGGTTGGGTGTTTGTGGAATCCAGGTATCATGGAATTGGAGTTTATATACATTTGGGCTGCCTGTGAGTTTGGGTGTTTGTGGTTGGGTGTTTGTGGAATCCAGGTATCGTGGAATTGGAGTTTATATACATTTGGGCTGCCTGAGAGTTTGGGTGTTTATGGGTTGGGTGTTTGTGGAATCCAGGTATGGTGGAATTGGAGTTTGGGATGTTTCTAGAATTGAGGTCATCTGTTGGTTTAGGGTGTATGTGGTGTTCATTGATGGTGCGGTTGGGGGTGTTTGGAGACTCGGAGGTTTGGACTTTACAAGATTTGGGAGTTTGCAGCTTGGGGACTTGCAATTTTCAGTGTGGGTTTAAAGATTGGCTACTTCGGGTTCATGTATAGTTGGGGCATTTGGAATTGATTGTATTTATTAGGACTGGGGTGTTGGAGGTTTAGGCTGGGTTTGGGGTGCTCTAAGATTTGAGGTTTAGAGGTTTTGGCGTATGTGGGTTTGGGTAGGTAGAGTTGAGGGTGTCCGGGAGTTTGAGTGTTTACATATTTGGAGTGTTTAGAGAGGTAGAGGTTTAGGGTTTGGGGCATGTGTGGGTTTAGGCGATTGTGGGTCTGGAAGTCCAGAGACTTGGAGGAGTTGCTGACGCTGGTTGGAAGGTTCAGGGTTTGGTGGGATGTGTGGCCCCCTCGTTGCCCAGGCTTTCAAAGGCCAGGCCCAGCTGGCTGAGAGTGGGAGTCATGGTGGCTGCTGTCCTGCCCATGTGGTTGAGACGGTGGCAGTGCCCAGAGAAGATAATGGCATTGGCAAGTGCGCCGGCAGTCACTGGATCCTCTCCAGGACCAGAGGCTGGGGCACACAGCCTGCCAGGCGCTGACTCCAGTGAGGACTGGCGTCTCACATCCGTGGAATGACAAGCCCACTCCCGTGCCCCACTCCGACAG
Seq C2 exon
GTACTCTATCATCACCCCCAACATCTTGCGGCTGGAGAGCGAGGAGACCATGGTGCTGGAGGCCCACGACGCGCAAGGGGATGTTCCAGTCACTGTTACTGTCCACGACTTCCCAGGCAAAAAACTAGTGCTGTCCAGTGAGAAGACTGTGCTGACCCCTGCCACCAACCACATGGGCAACGTCACCTTCACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-C3:NM_000064:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACTCCTCCCCATCCTCTCC
R:
GAAGGTGACGTTGCCCATGTG
Band lengths:
326-1438
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)