HsaINT0024060 @ hg19
Intron Retention
Gene
ENSG00000138658 | C4orf21
Description
chromosome 4 open reading frame 21 [Source:HGNC Symbol;Acc:25654]
Coordinates
chr4:113469409-113475138:-
Coord C1 exon
chr4:113474991-113475138
Coord A exon
chr4:113469537-113474990
Coord C2 exon
chr4:113469409-113469536
Length
5454 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
ACATTTTTGTTGTAATAAAGGTT
3' ss Score
5.52
Exon sequences
Seq C1 exon
CTTGCATGCTGGCTCAGAAAATGAAAGTGAACAGTTAAAAGAACTACATGCACTAATGAAAGAAGACCTGACTCCTACGGAAAGAGTCTATGTGAGAAAAAGCATTGAGCAGCATAAACTGGGGACCAATAGAACCCTGCTGAAGCAG
Seq A exon
GTAAGAAGTAGTAGCTTCAATTTGTTTCTTGATTTATATATACCATTCAGATTCTCTTATTTCTGTTGATGAAATAATATTTCCTTTAAATAAAACAAACTGCTATGATAGTTTATATTCTACTAAGGTGCATGCATGTGGATCCTTGGATATAGTCTACCCAGTGTATGTTTTATGTTTGCTTCAAAGCATTCTTCAAATTCGTGAATAGATCCAACTCACCATGACCGAGTCATCCTTTCTCCTTCTCCCTGTTTACTTTCTTTTTATAGGCTTGAAGAGGAAAGTATAGAGGTGGGAATAGATTCCTTACAAGTTAAATGAAATTAGTTGTATTCTAGGAGAAACAGTGATGGAGAGGATCTGACCCTGAGTAAAATATCCAAATGAAATTTGTGTTTGATGCTCTCCAAGAAAGCCAAGACTTTTAGTGTTTGTATATATCCAAGAATCCAGGAGGCTCAGACGCTAGCTTCCAGGTATTGGAAGCCAAGACTAAGCACACAAGATTCCAGGCTGTAACAGGTAGCACTATCTCCTTTATCAAGTTTTGATCTAGGGAAGCCTGGGCATCAGCTGTTGGAAGAGAAAAAATCAATCAGCAGCTTCCTCCTATGAAAGGAGAGCATGGGGAAAAGCAATGGGGATGGAGTAAAAGAAAGTTGTTGGCTTCTTGGGCCACTTGCACATTGGTAACTTTCTGCTAGAGAGTTGAGAAAATGAGTCTACTTGGGACACTGTATTGATCAGCTATTGCTGAAATAATGAGGGTTAACAAACTCAGTCTCAGTACTTTAAGACAACAGCTTATGACTCTACAGGTCAAGTGGTGTGGCTTGGCTTGAGGCTATGGGTAAAGTCTCTTATTCTGAGAACAGTTGCTATGGCATGATCTTCTAACAGATGGCAGAAGTGCAAGAGGGCAGGACAGATCACAGAAACACATTTAAAGCTTCAGTTCATATTATGTTTGCTGACATTCCATTTGCACAGGTCACACGGCCAAGCCTAACATCAGTGAGGCAGGGAAATATACTCCCCTACTTCTCTGGTGGGAAGCACTGCCAAGTAACATGGCAAAGGGTGTGGATATGTAATAATACTTTCCTAGGGCGGGAAGGAGAAACTGAAAATAATAACCAATCTATAACAAGTTTTGGTTCTGGAAGTCCTCAGAAAACTTCAGACTAACTTTCTGTTATTTGAATTATAGAGTTAACTCTATACTCTCTTCTTAACCAAATCCAGAAAGGCTTAGTTTGGCTGTGTTCAATTAATACAAATTAGTCATTTATGTAAACTACTTATCATTTTACTCACCCAACGTAACAATGATATATAAGAATCATTATTCATATATATCATTGTTAATGATTTCTTGGATGATTTTCTGAATGAAAGCCCAGTTACTATGATCTATTGCTCATTTGTATCACCTATTCACAAATGAAAACTATTTTAGAGGAATTATTTTTTAGAAATTTTCTCTGACATATTTCTAAGGTCCAGCCAGGCATTCGGACCTGACACATTTCTTTCTTTCTTTTTTTTTTTTTTTGAGCCAGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCAGTCTCAGCTCACTGCAACCTCCACCTCTTGGTTCAAGCAATTCTCCTGCCTCAGCATCCTGAGTAGCTGGGACTACAGGCACATTCCACCGCACCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACAGTGTTGGCCAGGCTGGTCTCAAACTCCTGACCTTAAGTGATCCTCCCACCTCTGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGAAGACCTGACTCATTTCTAAAGTGGCATGTCTTCACAATAAAACTAATTTTTAAAAATGCTTCATAGTTAATTAATACTTGCTAGGTCAGTAACAAAATCTTTTCTGCTGTTAGAATCTCAGCAACATAATAATAAATAAAAAGATAACATAATTTTTTAAAGAAAACTTAATACTTTAGGTTTTTGTATTAGATATTTCTTTAAATTTAAAAAATGCTTCTTGACACATAACTTTAGAGTTCTCATTCTAAGATTGTTTTGTAGATATAGTTGCCAGAAATTAAATAAAATGAATAATATTTCAGAGTGGCACCAAAGCTTGATCATTTTTAAAGAACTCAATATTTAAATACTGTGGAATTTCTGATATAAATGTGGCTTTAAGATTTTTGTTTTTGTTTTTAACAAAAGAAGAAAACCTAACTGATACAGGGCTATTGTGTGTGGTGAATATTATTTATTATTAAAATAAGGCAGTTGTAATGTTTTCTTATTTTGTAGGATCTGTGGAGGCAGTATTTAATTTGTAAAGCATATTTTTTGTTAGTTTGTTGAAAAAAGGTATGGTCAGTTGGTATGAACTGCCCTTGCTATCAAGAAGTGTAATTTTATAGATCTTCAGATTGTTAGAAGAGAATAAGTACAGTCATATATCATTCTGAGAAATGTATTGTTTTACAATTTTGTCATTGTGTGAACGTCATAGTGTACTTACACAAACCTAGATGGTATAGCCTACTACACACTAGGCTACATAGTATAGCCTATTGCTCCTCAGCTACAAATCTATACAGCATGTACTGAATACTGTAGGCATTTAATTGTAACATGGTGGTATTTCTGTATCTAAACAGAAAATGTACTGTGAAAATATGGTATAAAATATTTAAAATGGTACACCTGTATAGGGAGGGAGGGAAGGAGAAATTGGAAATAATAACCACAAAGTTTTGGTTGTAGAAGTCCTCAGAAAACTATATATACTATAGCTTTTTAATAGTTAACTTTATAGTTAACTGACCATGAATGGAGCTTGCAGGACTGGAAGTCACTGTGGCTGAGTCAGTGAGTGGGTGGTGAGTGAATGTGGAAGCCTAGGACATTACTGTACACTACTGTAGACTTCTAAAAAAATTTTTAATTTTTTTGAGATAGAATCTTGCTCTGTCCAGGCTGGAGTGCAGTTTGTGATCTCAGCTCACTGCAACCTCTGCTTCCTGGGTTCAAGCGATTCTTCTGCCTCATCCTCCCGAGTAGCTGAGATTACAGACTCCTGCCACTACGCCTGGCTAAGTTTTGTATTTTTATTAGAGATGGGGTTTCACCACGTTGGCCAGGCTGGTCTCAAACTCCTGACCTTAAGCGATCCGCCTGCTTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTACTGTAGACTTTATAAACGCTGTACAGTTAGGCTACCCCAAATTTATTTTAAAATTTTTTCTTTCTTCAATAATAAATTAACTTTAGCTTATTATAACATTTTGACTTTATAAAGTTGAAAATTTTTAAAAACTGTTTGATTCTTTTGTAATAACACAGCTTAAAACACAAACATTTTGTATATACAAAAATATTTCATAAGCTTTTTTATTTAAAATTTTTCTTTTTTTACCTTTAAAACTTTTTTTTTTAATTGTTGAAAACTAAGATACAAACACATTATTCTAAGCTTACTCAGGGTCAGGATCATCAATATAGCACTGTCTTCCACCTCTACATCTTGTCCCACTAGAAAGTTTTTTTTGTTGTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAAGCTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCACCGCCACCACGCCCGGCTAATTTTTTTGTATGTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCTTGAGCCACTGCGCCCAGCCTTGTCCCACTGGAAAATTTTTAGGGGCACTAGGACACATGGGGCTGTCAGCGCTTATGATAACAATACCTTCTTATGGATACCTCCTGAAAGGCGTCCCTGAAACTGTTTTATAGCCAACTTTTTTTTTTTTAAGAAGTAGGAGTACATTCTAAAATAATATTAAAAGTATACTATAGTAAATGTATAAACCGCTAAAATGGTCATTTATTATCAAGTATTATGAACTGTACGTAACTGTATGTGCTATACTTTTATATGACTGGCAGTACAGTAGGTTTGTTTACACCGGTATCACCACAAATACATGAATAAATGCATTGTGCTGTGAGGGTTGTGATGTCACTAAGGGCTGGGAATTTTTCAGCTCCATTATAATTTTATGAGACCATCATCATACATCTGGTCCATCATTGACCAAAACATCACATTGTTATGTGGCACATGACTGTATATGTATATGTACATGTATGTGTATGTGTTTGTGTTTATACACACGTATGTATATGTACACAAATGTGTGTGTACGTGTGTATATGTGTATGTACACATGTGTGTATAGATAGCGGGCTACTAGGTCAGTGACTACATCTAATTAGAAAATTCATAGATTTCCCTATTGTTTACATCTAATTCTAGAGATTAAAAATCAGTTTTTATGAAGCTTTTTGCCTTGAGAGTAATGGCATGCTGCTATAATGTGTAACTTACAAGATTCAAATACACTTACAGGCTATGAGTACATTTTATTTACTGTTGTTTAGAATTAGTCATCTTTACATTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTTTTAGCCGGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCATCTTTACATTTTTAAATAAATAAAACTAATGTGCTTGAAGGTTAAGCAAAGAATATTTCGTTAGCATATTTAATATTCTTTGTGAAGAACTTTGGCCTGTGTTGATATAATGTATGTTGTCTAACCTCATCTAGAAGATAAAATATGTGCGTCATCCTAGATGTTTAACAAATGCTTGATATTGTGATACTTTCCGTCTGAATATCAAAATATGTCTTTTATTTGTTCTTGTTAATGGGCTTGTGGCTTAAGTAACTTACATTTGTTGATTTCCATTTTGTATGTAGGAATAATAAAAATTTGGAGATACGATGACCTAAGATTTCTGATGGCTAGGAATTAAATTAGGACTAGCTCACTCTCTAATTTTAGCCTACAAGTTCTTTGGTAAATACGTTCTCTTATTTTCTTTTAATAATTGTTAATTAATAACATTTTTGTTGTAATAAAG
Seq C2 exon
GTTCGAGTAGTTGGAGTTACCTGTGCAGCCTGCCCATTCCCATGCATGAATGATCTTAAATTTCCTGTAGTTGTGCTGGATGAGTGTAGTCAGATAACTGAACCGGCCTCTCTCCTTCCCATTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138658-C4orf21:NM_018392:22
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF130861=AAA_11=FE(29.0=100)
A:
NA
C2:
PF130861=AAA_11=FE(17.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)