HsaINT0036450 @ hg38
Intron Retention
Gene
ENSG00000179335 | CLK3
Description
CDC like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2071]
Coordinates
chr15:74620009-74622216:+
Coord C1 exon
chr15:74620009-74620225
Coord A exon
chr15:74620226-74622119
Coord C2 exon
chr15:74622120-74622216
Length
1894 bp
Sequences
Splice sites
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
3' ss Seq
TCGGGGGGCGGTGCATGCAGAGA
3' ss Score
-0.12
Exon sequences
Seq C1 exon
CCATGACCGCCTGCCCTACCAGAGGAGGTACCGGGAGCGCCGTGACAGCGATACATACCGGTGTGAAGAGCGGAGCCCATCCTTTGGAGAGGACTACTATGGACCTTCACGTTCTCGTCATCGTCGGCGATCGCGGGAGAGGGGGCCATACCGGACCCGCAAGCATGCCCACCACTGCCACAAACGCCGCACCAGGTCTTGTAGCAGCGCCTCCTCG
Seq A exon
GTGAGTGGTAGCCAGAGTGTGCTGGCTGGGGCTTAAAGGCCTCATCTCTTCCTAGCCTTCTCTCAGGCTGGCTGGTCCGGGTGAGTACTGCCAGCCCTGTGCACGTGCACTGGTGTGCGTGCATGTGTGTGTGTATGTGTTGTCTGGTCCAGGTGTAGGGCTGATCACAGGGTCCTGGCCTCTGTGTCTTCTGGCTCTTTCCAGTGGCAACTGTAGGAACTCTGGCTCCGATGCTGGCTGGCCCCTGGCCTGTCTATGTCTACACAGTGCTCCAGACAAAGGCCACGTGGTGCAAGTGGCTGGGGACACTTCTTAGGACACTTCTTAGGGATCCTAGTAGAGTGGCTGGTATGGTGGTCTGCAGCTATATGGCCTGGTCCTTCCCACCCAGAGACTGCCTCCTCGTGTAACTGAGTGCTCTGATGTGGACTGCACCCACCTCTGCGTCTCATCTGCACACCCCTTCCCAAAGGCCCCCAGTCTGGAGTGCCTCACAGGACCGGAGGATTTGCCTGTCAGCCAGCTCAGACTGGGAACTTCCCTTCTGATCTCCAGCCAGGCCCTCTCCAGCCGAGCCTCTTTACGAGGGGCAGTCGCGGTGAGGAGGGGCAGGTGCCTGTGTGATGGGGCATGTGAAGAAATGGCAGAAAGGCTGCCGCCCCAGGCCTCGTCCAGTTGCAGGCCACATGCCCAGAGCAGGGCCTGGCCAGTATTCCTAGCATGGAGGGTTGTAAGGTCTCTGGAGCCCACATTGCGCTCAGTCCCCTGGGGAAGCAAAGCCAGTTGTGTATTTCCGAGGTTACGTGCGGTCTTCTCTTCTCCCCCATCCCTCTTCCCTGCCTCCCTCCTGCCGGCCTTGAGGCCCCTGAGGAGCAGTGGAGAGGCCAGGTGTCTTCTCTGCCCAGCGCTTTCTGTGACTTCTTTGAGTGGCTACAGGTTGAGGGTTGACTGTGCGGGCGATTGCAGCGTGGCCCTTTCACCTCTTTGCACACTGCCACATGCTGCCACAGGATGGCAGTGCAGGTCTGGCTCTGTTTCTCTGTTTGGTGCCCTCTATCGATCGTCGTGAGGCTTGGGATGGGCCTAGATTGTGAGCAGCATGGGTGCCAAGGCCAGGGCAGGAGCTGGCATGGGGCCTGTGTGGGCCATTGTGGTAGGAAGCCTGGCAGTCGACTGGCCCAGAGGATCCCAGGCTGCTTTCCTTCTTGAGGCTGGTGGCAGGAGGGCTGCTGACGGAAGGCTGTTTCTGGTAGTGATGGTGAAATCTGGCCAAGGATGCCGTCTGGAGGCAGGTAGCAGCTTGGCTGTGAGTGGCAGCTGTCAGGCATGTGCAAGTCTGCGTGGGCGAACAGAGGCAGGCAAGGACAGGCTGGGCATTCTGCAGCTGAAGCCGGAGCAGCCGCTGACCAGTCTGGATGGTTGGACCCAGGCGGGGCCAGCTGCCTTCTTGCGCCGCCGTTCTCACTGCATCTTCCGCTCTGGCCCAAAGCCACATGGGAGGGTCTGGGAGGGAGAGACTCGGAGGAGGAGGAGGAGGGAGTCGGGGCGATGGCTCTCCTCACAGCGTGGCCCTCAGCAGCAGAGGCAGGTCATCTTCCTGAGCGTTTGTGGCGCTCCTCTTAAAGATAATGTCCGAGTTTTCTTTACATACCTGTAGCTGTTTTTACTTTTCTGTTTTTGAAGTCAGTTTGTGTCTTGACGTGTCCCTTGCAATATCCCTATCGTTATATATGCTGTGTGCCTTATGAAATGCTGGGATCTGGAAAATCCAACCAACCAACCCACCGGCTCCTCACCGTCTCCACCTCTGCCTTTGACTGACACCTCAATCTGTCAATCGGAACCGCCTACCATGCGATTGGTCGGATGGCGTTTCGGGGGGCGGTGCATGCAG
Seq C2 exon
AGAAGCCAACAGAGCAGTAAGCGCAGCAGCCGGAGTGTGGAAGATGACAAGGAGGGTCACCTGGTGTGCCGGATCGGCGATTGGCTCCAAGAGCGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000179335:ENST00000345005:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.762 A=NA C2=0.424
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0006920=Pkinase=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCATGACCGCCTGCCCTA
R:
CTCTTGGAGCCAATCGCCGAT
Band lengths:
310-2204
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development