HsaINT0041229 @ hg19
Intron Retention
Gene
ENSG00000134376 | CRB1
Description
crumbs homolog 1 (Drosophila) [Source:HGNC Symbol;Acc:2343]
Coordinates
chr1:197407677-197411422:+
Coord C1 exon
chr1:197407677-197407805
Coord A exon
chr1:197407806-197411295
Coord C2 exon
chr1:197411296-197411422
Length
3490 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
3' ss Seq
CTGTTCTGTTTATTTTGAAGGTG
3' ss Score
10.2
Exon sequences
Seq C1 exon
ACAGAGCAGATTACCCTCAACAGTCTGTGGGAATGAGAAGACAAATCTCACTTGCTACAATGGAGGCAACTGCACAGAGTTCCAGACTGAATTAAAATGTATGTGCCGGCCAGGTTTTACTGGAGAATG
Seq A exon
GTGAGTCACATTAGAGCCTTCTGGAAGAGAATTCTGAGCTAAAGAATGATGGGATTACTCAAAGTTCATTTTCTCCTCTAATTTTTTATCTCAGTTCCCATAGGAAAATCTATGCTGAAATAGAGGTTCAGACAGAATGAAACAATAAAAAAGAAGAAAAACTACAGTTTAGGTCAAAGGGGAGAACATTTTATTAGACAAAACTTCAAATAGGGAAAAATGATTTTTAAAAAATGTATAATGTGCTATTTTTCTTTCTTATAAGTACTTCTGAATTCATGTCTCTTTTTTGTTGCTAACTCTAATACATGATGCAAATATGGTTGCTGTCGAGGTAAAATAAATTACAACTAAAAGATTGCCTCATAGAATTGCCTACAACCCAAAAGTATATATACCTTATCCATATGAGTCTACTTTTCCCAGAGAAACTCTTCAACTGTTCTTCACCTCATACAGGAATTCTTAAAATGGAGTTGGTCAATGGCTTCAGGCAATCTGTGACCTGCTGAAAATACAGGAAAATTAGAATATGTATTTGAGTGGCTAGGGGTAAGTTCAGGGGTAGAAATAATGCATACTGAATAGCTTTTATCAGCTGCTTAAAGGGATTTATGTCCCCAAAACAGTTATGAACTGGGGCTCTATAGAATACAGATACTATATAAGCAGATAATTGTTAACCTTTTGTTTTAGCACTGTGCCATGCACCTTACAAATACCATCTCTAATTCTTATAGCTCTGTAAAGAAGGTTTCATGATTTTTATTTTGCATATGTGTAAACTGAGGCTGAGAGGTTGAGTGACGTATAAAGGGCCTATCCACACGTTTGCTGCAGTAAGGTTGAGCTGCCTTCAAAGCCTCTGCTCTTCTATTTGATGTGCCAGCATAACTGTATGAATAAATCTTTGCTCAACACAATTTCTTTTTTTTTAATGAGAAAGGTGTTCTTCCATCTCATGTATCATCGAGGGTAAGATAAGTGATCTCTGATCAAACTTCCTACATTGAAAAAATTAAATAAACTGAGCTCAGACATATTTGACAAAGATATTTTGACTGACTCAATATTTCCCATAAGCATAGTTAATAAAATAATGGATATGTGAGTGCTCCCTGGCAAGTGCCCTTTGGATTAATTGGAATTTTCTGTTTTCTAGCTGGCCTCTTTTGCATCACAAAGACACAGGTCTTTTGCCATTTTTACAAAACAGCGGGGAGTCTAGGGTATACCTGAATTTGACCCTTTTAACGTTCATTTTCATTTGCAGCCTGCCTTCTGTGGTTGGTTCTTTGTGGTACAGGCATTCCAAGTCTATATGTGCATGAAAGGAGATAGCCTTGAGTCACATTCTGCTTTCTGTTGCACCAATTTTGGTTCTGCAACTTATTAACTGAGATCGTTTAGTTGTATTCCAATTCCATGTATCTTTCAAAATATTGCAAATATTTTCTTGTCATTAATTTTGAGTAATCCAACTATTGTCAAGGGTGGGTTGCTTCCTGGTTGAACGTCACACTTTCTGCCTAATGGCACAATGCATGGAACTCATCCAAAACCCTGGATTATTTTTCTCTGCCACTCACACATTGTTTCTATTTACAACAAATATCTCCCTGTCTTCTGATATTTATTAGTTTACAAAATTTATATTTGACATTTAAATTCAGATATATTTGAAATATAGAAAGAAAAGAAAGCTTAGAGTTTTCCTTCTTTTCCCAGGAGACTTTTCAACTGGAAAAACTTACATGATGCTAGATATTTCTAAAACATTGAACCTGTGTTCAGTAGATTCTATGCTTTCAAAGTCCTTAACCATCATTACTTAATTGACTAGATGTTAATGGATTTATTTTTACTTTTCATGCATTAATTAACCTCTAATAAAAATGCCAATGATGCTGATAATACATGTGTATCTATTGTTGACTGTTTAGTTCAACAGAGAAATAGGTGAGAAAGTGATGGAGTAGTTAGAGGAAGACAGAAAATAGTGGGCTATCTCCCATGGCCTAGGGAAATGTGACTTCCATCACATCCAAGGATATTGAAAAGCTATCCTCAAATAAATTGGCTTCTCTCCTGCCTTGGTTAAACCTTCAGCTTAATAGTGTCATCCTGGCAGGTTTTGAATGATGGATGGTGTGAACACTCTGGCCCACCCAAGACCGAGAATGCTTGGCAGGCTCCTGAGGGTTGTCAAGTTTTGCTCAGATCTAATCAGAGAAGTCTCCCTCCAGTCCAGAAGCATAAGCCAAAAAAGGAAAACAAAATGTCTCAGCTATGCTTGGTATCCAAAGGGATAAGGAGCTGTTTTTCTTGGAAGAAATCTTTGTTTTCCTTTATACCTTGGGCTGGCCTTGCCCCACTACCTCACCCCCTTTCATTTTGAGCCTAGTGATTAGTCTCTGACCCATACGTGCAAGTTTTACATTTTGGAAGGTGAGGGAAAGAATAAGGGAAAATTAAAAATTGTTTACATACAATTTCAACATTATAAGCTGCACTATAGAGATCTTGGAGCTAAGATTTTATATAAATTTTCAAAAGTAAAATAGCCGCCTTAGTTGCTGTTCTATCCCAAGGTCTTAGCAGAGTGTTTGTCACATAGTATGTGTTAAATAAATATCCACTGTGTGACTGAATACATGATTGGTGACTTAATCCATGAATATACAGAAAAACAAATTCTTGCTGGAAAATTAGTTTAAAAAAATGACAATATCCCAGGAAGAAGAAAACTTCAATTTACCTGAGACTTGATGTCACTTGTCTTGGAAAATTTGGCTTTTGAAAGTCATTCTACCTCAACATTTCAGAAATTATGCTTGGCTATTGGAACACAGATTTATTAGCAAGTACAATCTTCTAATTATTGATTTTTGCTTTTGTTATAAAAAAAGGATTTCCACAGAAAATAATTCAAAATCTCTCAGAATAAACCTCTCCTCTTCCTCCTCCTCCTCCTTCCCTCCTTCTTTTTTTTTTTTTTTTTTTTTTTTGGTTTCTCTTTGGTGGGCTTTTTCCTTAGCCTGAGGGCTCTGATGCATGAGGATCCTGATAGCCTGAATGTAGGTCTGCCCTGCAGACTCCAGATGGCAAAATACAGCCTCTCTCCTTGTGCCCCTAATAAACTGAACATTTATATAAGGTGGCAACCACACTAATGCTCTTGAGCATTGACACTGGTGTAGGCATGGCCCACTTTTCTCTTGGTTTCTAAATATTTGCATCTATTTTCTCATTCTAATTAATTCCGTGTGTATATGTATATATATGTGTACAGATTATTTCCATTAAACCCCAAATGTGTTAAAGAAATTTTAAGAAACATCTCCGACATTATCAAGTATGTATAAAGTATGTGTGGATGGGTAGATAAGACTGTGCTGTTCCAGAGAGATAAGGCAAACTTTTTCTTCCCATTTCACAACCAATGTATTCAACAGGGACCTGGGTTTCTGCTGTTCTGTTTATTTTGAAG
Seq C2 exon
GTGTGAAAAGGACATTGATGAGTGTGCCTCTGATCCGTGTGTCAATGGAGGTCTGTGCCAGGACTTACTCAACAAATTCCAGTGCCTCTGTGATGTTGCCTTTGCTGGCGAGCGCTGCGAGGTGGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134376-CRB1:NM_001193640:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=WD(100=68.2)
A:
NA
C2:
PF0000822=EGF=WD(100=72.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)