HsaINT0041857 @ hg19
Intron Retention
Gene
ENSG00000116791 | CRYZ
Description
crystallin, zeta (quinone reductase) [Source:HGNC Symbol;Acc:2419]
Coordinates
chr1:75175782-75180314:-
Coord C1 exon
chr1:75180263-75180314
Coord A exon
chr1:75175932-75180262
Coord C2 exon
chr1:75175782-75175931
Length
4331 bp
Sequences
Splice sites
5' ss Seq
GGAGTAAGT
5' ss Score
8.57
3' ss Seq
GGGTTATATTTGTTTTTCAGGTT
3' ss Score
9.39
Exon sequences
Seq C1 exon
TGCCTGTGTGAAAGCTGGAGAGAGTGTTCTGGTTCATGGGGCAAGTGGAGGA
Seq A exon
GTAAGTATTTTTTTTAATGTATTTTGAAACAAGCTTGGGTTTATGGGTTTCACATTATAGTTCCTTTGGTCATTTTTAAAAGTCAGATTTATAAATAGAGTCAAAGGTGCTTTTTTTCTTTATGTAGTAAAACTTTTGATTTTGGTCTTCTGAAGGTGATGTTTTGTCATTAGTTTAGCATTTCTTGGTTAATAAACTCAACAGAGCACCCCTTCAAAAATATGTTAGATTTTCCACCTGTATTGGGTGTAGACTAAGATAAACTGGCCTTGTTTTTGCCTTCAAGTAGCATATGTTATAAAAATATTTATTTAGAATTTTAAACAGTTCTTTAAGGTTGATATTAATTCCATATTCCCTTAGATAAGGAAACTAAGGCTCATTAAAGCTTACCTATGTTGCCCCAGACAGCACGGTAAAGCCACACTGTGAATTCTTAGTCCTTCTATCTCCCTTCTGCTGCTTGCCTGCTGCACTTTGATGACATCCATGGAGTGCACGTATACAGCCCTGTCCTTAACACCACAACCCATGGCTGAAAATGCTAATGTGGGGGAATGGGGGAGGAGGACTCAGAACTTAAAATAAGCCCTTCAATGAAATCACCCAATGCAGGGCTGTCAGAAACCTCTTCGAGAAACTAGCTGCCAATCTGCCTCTCAGGAGCTTAGAGGGAAAAGTTAGAGCTCTGCAGTTAGAATTTAACAAGAAATCCACATGAACTCTGTCACTGGATGCTTTGGAAATTTTGGAGATAAGATTTTGCATTTTAAAAATAAAAGGCCTGGGGCTAGATGCTTACTTTGAGGAGGCTGTTAACCATTTCAGAGCACTGTGTATTCTGGAGAGTGGATTGAAAGAAGTAACCTATTAAATGGCACATAGTCCCCTGAATAATGAGTGGTATCCTGAAAATGTGAATTTACCTTTAAAAGTGCCCAGGTAATTTCAGTCCTTTTTGTCTCTCTGTTTCTTTAGGTAGATGAATCACGAGGTTTCACACCTAGCTTCCTACACTTCAAATAGATCAATTCTAAAGGATTTCACAGATCAAACAATTTATGAAAAAACACTAGGATTGTCTTTATGGGGCTTGAGACAATATGACAGATATACCTTGTCCAAAACTCCCACTGTTTAACTTCACTGAAGAGGCTATTTTTGGGTTAAATTAAATTTAACCCTAAGTAACTAAAGGGTCTGTCAAACACATACATTTATTTAAATTACCCTGGCTTTCAGAGAGCTAACTTAGTGCTCTGTGCAGAAGGGAAAGATTTCAGTAGGAAGGGGAGAGAAGAGTTTAAAGAAAATCTCTTTATATTCCCTTTACCCTCTTGTAAAAAGCCCAGTTGCTTCACCATGATTTTTTTTTAAGGTAAAATCCACACTGTTCTCTGAGCTGGCTGAGTTTGTTAAATCCTCAGCTGGCAGGGATAGGCTGGTGACCTGGTGTGTGAAGTGCTTCTGATCCTCCCTGTCCTATCAGAGGGAAACAGTACTGGGTTTTGCCTTGCTTCTGTTTGTACTTTCTGTCCTCATTTAATTCGAATTCCTTTGGGATTATGTTGTGTGTTTAAAATGGTGTGGAATTTATGAACACAGCTATTATCCAGATATGTTGGTGAGGAGTGCCCTATTTTAGTGTTAGCAAAATAAGTAGAAGAAAAATAGTTGACACATAATGGTGCATAATCTGTTGAAGGATCATTGCTGGTATAATTGTTGACAAGAATAGAATAAACAGTGCCTTTTTAAAAGAGCTATTGAGTGCCCTTTTAAAGCAGTTAGAACACAAGGAGATGTAGTTACGTTAGCTTTTTAAAGTGTGGTTTTATTAGAGGTCTTTTATTTAAATTTGAAAATTAAAATAGAAAATTAATTGTGCCCACCCCATAGTGGGTTGTGTTTTATCTAATTGGATGTCTCTCTCCTCCATCAGACAGTGAGTTTCATGTATTTGTTTGTTTCAGTTAAACAAATTCCTGCCATAACCTGGCTGAGTCCAGCCTCGTTATTCCCATGTGCCATACAATCTTTAAGGTCCACTTCAGGCCTGGAAGTCTGTTACAGCTTTAATCTGTTTCTATCATTATTTTTCATCTTAATTCTTTTCTTGCCGAACCCGGTCCTCCCTGTAAATCACTGGTTATGAGTAGCGGGTGATTTTGCATCATTTCTCCTTCCGCTCTGGGACATTTGGCAATGTCTGAAGACATATTTGGTTGTCACAACTTGGGGAAGGGGTTCTGGCATCTAGAGAGTAGATATCCTTCAATACATGGGATAGTCTCCCACAGCAAATAATTATCTGGCCCAAAATGTTGATAGTGCCAAGTTTGGGAAACTCTGCTCTAAATGTATGTGACACTTATTTGTACCATCATTTGTCATCTAATCAGATATATTTCCTAGTATTGTTATTTAAGTAATTGCTCTTTTGTCTATATTCTTAAATTACTTTGATTTCTCTTTTATACTAAGCACATTTATCTGGTATTCTAGTGATTTCTTACAATCCCAGCATTTTGGGAGGCTGGGATTTTGCCAGGTTGCCCAGGCTGGTATCGAATTCCTGACCCCAGGTGATCCACTCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGTTCCACCTAATCCTTTGGCTTTAAATACCATCCGTAAGATAATGAATCTCTAATATATATCTCCAGTTGAACCCTTTTGAGTCCATACTCATATTCAACTGATTGCTGAACATCTTCGCCCGTAAGTAGATGAGCACTGTGCAGCTCAGCATGTTACAAGTGATTCTTTTATTTTTATTTTTTAGAGACAGGGTCTTGCTCCGTTGCCCAGACTGGAGTGCAGTGGCATGATCACTGCAATCCCAAACTCCTCAAATTCCTGGGCCCAAGCGATCCTCCTGCCTCAGCCTCCCACATAGCTGGGATTACAGGCATGCGCCACCACACTTGGCAAAGTGAAATCTGGAGATTTTCACAAACTTAGTGTTCTCCAGTCTTCTCACTCTACCCAGTTAATCTGGCCAAAGACATAGGAGACAGCCTGTATTTTTCTCTTTTCCTCATCTCCCGCATTCAATCTGTGAGGAAGTCCCATTAGCTTACCTCTAAACTATATCTGAATTTGTTTATTTTTTCCAGTGCCACCACCTTTGTTCAAGCCAGCTTCATCTCTTATCTAGACTGTTCTAACAGCTACAAACTGATCTTCCTCCTCCCATTTTCCTCACCGCTTTCTTTGTGCCTCACATGTAATTGGAGCAACCTTTTTAAAGCCTGAGTCAACCAGATCATTTCCTGGCTTAAGCTCTCCCGTGGTTCTGCACAGGTTTTAATATACTCGGAAGCCTCTACCCTCACCCCTCAGATTCTGTGTGACTTGGCCTTTCTGGCCTCATCTTCGACCCTTTCGTACACGCCCCTCCCTGAGACACACTGCCCCTCTTTCTGTTCTTTGACCCCAACTGCATTCCCACCTCGCCAGGTTAGCCATGGCCATTCACTATGCCCACAGCATCCTCCACGTGGCTGACCGGATGTTCTCGTGGCTTGTTCCTCACTTTTTTCAGGTCTCATTTTTTCAGAGTGGCTCTTCCTGATGACCTAAATAGCCCCTATTCCTGTCTCTTTAACCCAACAGCCAGTCTTATTTTTTCTTAGCACTTTTATTTCCTGAATTTATTTTATTCATTCATATGACTATTATCTTCCTCCACCCTTAGAATATAAGTTTATTTCTTACATTAAGTACCATGTCTAGCACATCGTAAACACTCTATAAACATTCACCATATGGATGAATTAGTTAATTTGCCCATATACCTATCTCTTCTACTTAAATGGTGGAGGCCTTACATTTGTTATTTAGAATTTCATATGCACAAAGAAGTCAGAGAGCATGTTCTGATCATCTTTAAACCCTGCAAACATCTTGATGCAGTGGTTAAAAACTCAAGTTCTGCAGTCAGACTGGTCTAACTCCTGTTTCCATCTCCGCATATGACTTGGCCAAATTACTTATAATTTGAAGCTTCAACTTTCTTATCTGTACAATAGGGACAATAATAGTATCTACTTTATAGGGTCATTGTGAGGATAGAATAAAACAATATGTAGAAATTATTTAGTATGGTTCCTGGAATATTTTAAATGCTCAATTAAAGTTAGCTGTTTTTCTTATTTCTTCATTTACACTCTTAAGTTCCTTAAAGTTAGGGTGGGTCCTATAGGAATCTTAAGTTCATTGTATGTATTTAAGTGTTTACAGGAGTGTAGAGAATATATAACTCTTGGGTTATATTTGTTTTTCAG
Seq C2 exon
GTTGGATTAGCAGCATGCCAAATTGCTAGAGCTTATGGCTTAAAGATTTTGGGCACTGCTGGTACTGAGGAAGGACAAAAGATTGTTTTGCAAAATGGAGCCCATGAAGTGTTCAATCACAGAGAAGTGAATTACATTGATAAAATTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000116791-CRYZ:NM_001130042:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF122423=Eno-Rase_NADH_b=FE(32.1=100),PF136021=ADH_zinc_N_2=PU(8.8=72.2)
A:
NA
C2:
PF122423=Eno-Rase_NADH_b=PD(47.2=50.0),PF136021=ADH_zinc_N_2=FE(33.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)