HsaINT0044267 @ hg19
Intron Retention
Gene
ENSG00000138115 | CYP2C8
Description
cytochrome P450, family 2, subfamily C, polypeptide 8 [Source:HGNC Symbol;Acc:2622]
Coordinates
chr10:96798654-96802834:-
Coord C1 exon
chr10:96802647-96802834
Coord A exon
chr10:96798796-96802646
Coord C2 exon
chr10:96798654-96798795
Length
3851 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGC
5' ss Score
10.22
3' ss Seq
ATCTGTTTTGTTACTTCCAGGGC
3' ss Score
9.83
Exon sequences
Seq C1 exon
CTAAAGTCCAGGAAGAGATTGATCATGTAATTGGCAGACACAGGAGCCCCTGCATGCAGGATAGGAGCCACATGCCTTACACTGATGCTGTAGTGCACGAGATCCAGAGATACAGTGACCTTGTCCCCACCGGTGTGCCCCATGCAGTGACCACTGATACTAAGTTCAGAAACTACCTCATCCCCAAG
Seq A exon
GTAAGCTTGTTTCTCTTACACTATATTTCTGTACTTCTGAAATTTCCATAGTGCTGGTTTGGTTCCAACCCTCTAACAACACAAGATGAGAGAAGTGCAAAACTCATACATGTGGCAGCTTGATGGACTTTCTGCTATTTTGTTTGGGGCTATAAAGATTTATAAAGCTAGGTCTCCTTAATAGGCTGCTCTTAGGTGTTACACTTTCAAATAATTGTTGAAAATATCAGTGTGTCAATTTCCCAAAACACTCTTCTGAGATTTTTATCAAAGTGACATTCATTGTGTAGTTCGATATGGAAAGACTTAACATGTTCATGCATTGAATTTTTTAATTCATGAATATGGTTATGCTCCCAACTTATTGAGCTTTATTCTATTTTCTCAGTAATGTCTTATTTTCAGTGCAGTGGTTTACAACTCTTTTATTAGGTTTTTCCTAGATAATTAATATTTTGTTGTGTTATAATTTTTTAATTTTTTTTTATTTCTTTGTAATTGGTATAAGTAATTGTATTCAATTATACTATTCTGATGACCTTATATCTAACAACTTTCCTAAATTTACTGATCATTGCTGATAATTTATCTGTAGATATACTTGGAATTTCTATGTATATTATTTTGCTATCTGGGTTAATATGTATTTTATATCTTATTTTCCAATGATTTTGTCTTCAATTTATCTTTATTGCATTATTGTGCTGGCTAGGATTTTCAGGTTAGCATTGAACAGAATTGGTGATAGAGGGCATCCTTATTTCATTTCTGATCTGCTGGGGGGTAGAGTATAAGAATATTAATATTTCACTACTGAGAATGATGTTTTAAGTATTTTTTTAAAATAATTGACTTTTATTTAACTTCATTTATAAAAGAATTTTCACGAATATGGTTTGAAATGATACTCTACATTTGTTATGAAACAGATAGTTGGTATTTTCATAAAATCCCAGCCCCCAGAAGGCTCATGTCATTCCAAGTGATCAGACTCCTGTACCTTCCCTAAATAAGGCTAGCAAACTGGGGATGGCAGGGAGCAGAGCCCAGAGCACCTTGGTAGTTTTGCACAGATTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGACTACAGGCGTGAGCCACCGCGCCCGGCCTTGCACAGATTTTTTAAAAGCCAGTAACTTCCTTCTGGCTGTTCTAAAAGACAAACACTTTGGAGAAAAGTTGTGCAGTAAGGGAAACTATCAAAAATCATTCTCATAGAACAGTAAGGCAGTGAGGCAAACACGATCTCCCTCATGATTTTAAAGTCTGTAATAGAAATTAACAGTGTCATCTGCAGCCCAATTATGCACTTTAAGATCCCAAAAAATTGCTGCTGTTTTAAGTATTTTAGTAGATATTCTTTATCAGAAATCTTTAAGATTTTAGTAGATATCCTTTATCAGATTAGGGAAGTTTTTTCTCTTCTCTCATTTTTATATAAATTTGTGTCATGAATGTGTGTGCAATTTTATCAAATTGATTCTCTGCATCTATTTATATGATTGTATATACTGGCCTCACATCCCTCACTAAATATACATAAGTATACACAAACAGCTGGATTTGTTCTGTTACTTATTGTTCAGGACTTCTGTATTCATAAGATATTTTGGTCTGCAATTTTTCTTCCTCAAAATTTTCTTTTCAGAGCTTTGATAACAAGATAATGCTGGCTGCATAAAACTAGGTGAGAAACGTTCCCTAATGTGGGTCTGTTTTTATTGCTTTCCCTTCCTTCCACTTTTCTTCGTGTGACTGCTTAGTTGTATCCTTGAAATGCCTAAAAACCTATGGCTCAGTACCAGATATTATATATGAAAAAATGCAGAATTTCAGAGAACATTTATCTTTTTCCAGAATGTATTCATTCCCCTCTCATAGGCAATTATAATGACAACACCTCCTGTCCTGATTCAGAATTGAATATGACATGAACACAGTCAAAAATTGACTGTAGGTATGAGCTTACCTCTCTGAAGTTCTTCCGTCACTGGGGCCAATTATTGTCTTTATAATCTGGAGGCCAATTTTGGTCTTTGCAGCTTTACAATGCTGTCTATCACATGGTTTCTGTATTCATCCAGATGTTTTAGTTGCTATGCTATAAACTACACAATTCCACTTATTATTTTTCAATTAAAAATAATAAAGGTTATATCTTCATGAAGGAAAACAATGAGACTGATAAGGTTTCAATTACTAATGTCATCCTCTGGAGAAGACAGAATTGATAACTTATCAAGATGTGATGGGGTTTTCCCTAATTATCACTGATTTTTTTACAAGGATTAGGACTACAATCCACAGTTTTCATCAAAGCACACAACCAGAAGAGGTTTTTCTTTCTCAATACAAGGGTCTATCTACACCTCAATACTGCAGTATGTAATGCCCCAAAACAAAGATTTTTCTTTTACACAATAATAGTCACACTCAGTAGCTATTGTTCAAATAATAATACAGCCTAAATTTAAATTTTCACAATTTTTCTAGAATATTTTTATGGCTTTTTTCTCCTGCAGTTTACTATACAGGCAAGGAACAAGCATATAGTTCATTTATGTTGACCTTTTCACCTCCTGTAATCAAGGAAAGTTCCTTTCCTGGTTTGTTTCTTTTCAATCAGTTGACCTTTTTGAGACCAGCAGTCATTTAAAATGTTCCTCAGGCTGGTTTTGTATGACTGTTTTCTAGAGGCAGATTCCAGCTACAATTTTGGCAAGAAAACTACATAGGTGCTTTAAATATCCTGCTGAATCACATTGATGAGGTGGGAGCATGAAATGTCACATATGTCATTATTGGTCATGCTAAGTTCCCCACATAATAAGGTTGTATCCTCCAGATCTTACCATTGTAGGGGTTCTGCTTTTTATATGCAACTAGTAAAAATCTATGGGAGTGCATTAAGATTATCCGAAACTCCTGCTTCCAGAATCACACACCCAACGGTTCTAGCTTTAATTGATGATCCTTACCTGACCTGATGATCCTGACTTGAATTGTTGCAAAGTGATAATCTTTGTAATTTCATCATCTTTTCAGTGTTTTAAGCTAAAATTAATCTGTAGCATGGCAGTAATAAACACACAATAGTTTTTACTTCTTATTGCACTTGTGGTTGTCATCCCAGATGACATCATATTAAAATAGATTACATGTTTATTTACAAAAGTTCTATGAACAGATACTCTGGACATTTCAAGTGTCAACAGAGACTTCCATTTTAAACCATAATCTACATAATCAAAATACAAGATGTGTCAAATTTGAAGTGATGAAATAGAGCGGCAAATGAGGCCAGAAAAGGGCATCCAAACTTGATGATCTGGAGAACACATTCAGAAGGTTGCACACAAGTATCCAAGATGTAAGACTTCAAATGTGATTGGAAAGCTCTTTAGCAAGCTTCCACCACTGGCCTTAAGCTCATCCATGTAAATTACTGTGTCTGGCTGGACCTGAGTTTCCTCATCTATAGATCAACGTTATGGCGCTACGTGATGTCCACTACTTCTCCTCACTTCTGGACTTCTTTATAAATCAGATTATCTGTTTTGTTACTTCCAG
Seq C2 exon
GGCACAACCATAATGGCATTACTGACTTCCGTGCTACATGATGACAAAGAATTTCCTAATCCAAATATCTTTGACCCTGGCCACTTTCTAGATAAGAATGGCAACTTTAAGAAAAGTGACTACTTCATGCCTTTCTCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138115-CYP2C8:NM_000770:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.103 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(13.5=100)
A:
NA
C2:
PF0006717=p450=FE(10.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)