HsaINT0044298 @ hg19
Intron Retention
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450, family 2, subfamily E, polypeptide 1 [Source:HGNC Symbol;Acc:2631]
Coordinates
chr10:135346196-135347401:+
Coord C1 exon
chr10:135346196-135346372
Coord A exon
chr10:135346373-135347259
Coord C2 exon
chr10:135347260-135347401
Length
887 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGC
5' ss Score
10.08
3' ss Seq
GTCTGTCTCCGGTATCACAGGAA
3' ss Score
5.93
Exon sequences
Seq C1 exon
CTTTACAATAATTTTCCCAGCTTTCTACACTACTTGCCTGGAAGCCACAGAAAAGTCATAAAAAATGTGGCTGAAGTAAAAGAGTATGTGTCTGAAAGGGTGAAGGAGCACCATCAATCTCTGGACCCCAACTGTCCCCGGGACCTCACCGACTGCCTGCTCGTGGAAATGGAGAAG
Seq A exon
GTAGGCTCGGCCCTCCCATGATGTGGGCTCTCCGGGGTGGGCAGAGAATGCACAATTTCAGATTTACAGAGTGAGCTGCACTTGCTGGTGTCCAGACCTCCCACCGCAGCATGCTCTGAGTTTCATACACACACTCTTGGCTTCAGCATGACCACTGGACGCAAGTCAGCCTGCCTGGCTGCCAAGCTGGCCTGGGGCTTTGGGGTCACATGGGCGGGACGCTTAGCTCTCTCCAGGCCCTGCTGCTCAACCCTTTCTAGTCTGCAGACTTTGAGAATTGCATTTTGTCTGAGGAGAAGCCCTCAGCCTTCCTTGTGGGCATGCACTCCCCAACTGTGCGCAGCTGCAGGACTTCCAGGCCTCCCCAGCTTCATCCACCTGCAGGTGCTCAGGATCCTGATCCCCTGCCCCCTTCCCACCTTGGTGAAACTTCTTGTATCCTTGTCTTGTCCTTTCCTATGGCTTGTGGCTCAAGAACAAATGTGGAGCCCACACTGATTTCCCAGGACTGTCTGAGCATCTTCTCCACCAGTTTGGCCCCTCGTGGCAGCAGACACTAGCCCTGTAGCAGGAGGGGTTAGCAGGAGCCGTTTAGCTCCTGCCTGAGCTATGACCAAGGTCAGGGGGATCTCACCTCTCCCAGGATGGCCCTCATGCTGTGGAGGGAGACAGAGCCCTGGCCTGCCCTCAGCAGATTTCTGGGAGCCTCAGTTTCCCTGGCTGTGAGGTGGAGATGACTCTGTCTGTCACAGCTCCAAGTCACAGTTCCACTGGGAGAGCCTCTTGGACACTGTCTCCTGTGTCCCTGTGGAGCTGGGAGGTGGCTGGTTCTGTGCTGAAAGGAGACAAGCAGCCCCTTCTCCTCCGGTCTGTCTCCGGTATCACAG
Seq C2 exon
GAAAAGCACAGTGCAGAGCGCTTGTACACAATGGACGGTATCACCGTGACTGTGGCCGACCTGTTCTTTGCGGGGACAGAGACCACCAGCACAACTCTGAGATATGGGCTCCTGATTCTCATGAAATACCCTGAGATTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649-CYP2E1:NM_000773:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.017 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(12.7=100)
A:
NA
C2:
PF0006717=p450=FE(10.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATTTTCCCAGCTTTCTACACTACT
R:
CTTCAATCTCAGGGTATTTCATGAGA
Band lengths:
310-1197
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)