HsaINT0044298 @ hg38
Intron Retention
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]
Coordinates
chr10:133532692-133533897:+
Coord C1 exon
chr10:133532692-133532868
Coord A exon
chr10:133532869-133533755
Coord C2 exon
chr10:133533756-133533897
Length
887 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGGC
5' ss Score
10.08
3' ss Seq
GTCTGTCTCCGGTATCACAGGAA
3' ss Score
5.93
Exon sequences
Seq C1 exon
CTTTACAATAATTTTCCCAGCTTTCTACACTACTTGCCTGGAAGCCACAGAAAAGTCATAAAAAATGTGGCTGAAGTAAAAGAGTATGTGTCTGAAAGGGTGAAGGAGCACCATCAATCTCTGGACCCCAACTGTCCCCGGGACCTCACCGACTGCCTGCTCGTGGAAATGGAGAAG
Seq A exon
GTAGGCTCGGCCCTCCCATGATGTGGGCTCTCCGGGGTGGGCAGAGAATGCACAATTTCAGATTTACAGAGTGAGCTGCACTTGCTGGTGTCCAGACCTCCCACCGCAGCATGCTCTGAGTTTCATACACACACTCTTGGCTTCAGCATGACCACTGGACGCAAGTCAGCCTGCCTGGCTGCCAAGCTGGCCTGGGGCTTTGGGGTCACATGGGCGGGACGCTTAGCTCTCTCCAGGCCCTGCTGCTCAACCCTTTCTAGTCTGCAGACTTTGAGAATTGCATTTTGTCTGAGGAGAAGCCCTCAGCCTTCCTTGTGGGCATGCACTCCCCAACTGTGCGCAGCTGCAGGACTTCCAGGCCTCCCCAGCTTCATCCACCTGCAGGTGCTCAGGATCCTGATCCCCTGCCCCCTTCCCACCTTGGTGAAACTTCTTGTATCCTTGTCTTGTCCTTTCCTATGGCTTGTGGCTCAAGAACAAATGTGGAGCCCACACTGATTTCCCAGGACTGTCTGAGCATCTTCTCCACCAGTTTGGCCCCTCGTGGCAGCAGACACTAGCCCTGTAGCAGGAGGGGTTAGCAGGAGCCGTTTAGCTCCTGCCTGAGCTATGACCAAGGTCAGGGGGATCTCACCTCTCCCAGGATGGCCCTCATGCTGTGGAGGGAGACAGAGCCCTGGCCTGCCCTCAGCAGATTTCTGGGAGCCTCAGTTTCCCTGGCTGTGAGGTGGAGATGACTCTGTCTGTCACAGCTCCAAGTCACAGTTCCACTGGGAGAGCCTCTTGGACACTGTCTCCTGTGTCCCTGTGGAGCTGGGAGGTGGCTGGTTCTGTGCTGAAAGGAGACAAGCAGCCCCTTCTCCTCCGGTCTGTCTCCGGTATCACAG
Seq C2 exon
GAAAAGCACAGTGCAGAGCGCTTGTACACAATGGACGGTATCACCGTGACTGTGGCCGACCTGTTCTTTGCGGGGACAGAGACCACCAGCACAACTCTGAGATATGGGCTCCTGATTCTCATGAAATACCCTGAGATCGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649:ENST00000463117:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(12.7=100)
A:
NA
C2:
PF0006717=p450=FE(10.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATTTTCCCAGCTTTCTACACTACT
R:
CTTCGATCTCAGGGTATTTCATGAGA
Band lengths:
310-1197
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development