HsaINT0044300 @ hg38
Intron Retention
Gene
ENSG00000130649 | CYP2E1
Description
cytochrome P450 family 2 subfamily E member 1 [Source:HGNC Symbol;Acc:HGNC:2631]
Coordinates
chr10:133537063-133537892:+
Coord C1 exon
chr10:133537063-133537250
Coord A exon
chr10:133537251-133537750
Coord C2 exon
chr10:133537751-133537892
Length
500 bp
Sequences
Splice sites
5' ss Seq
AAGGTTAAG
5' ss Score
3.39
3' ss Seq
ACAGTCTTTGTTTCTCCTAGGGC
3' ss Score
9.31
Exon sequences
Seq C1 exon
AGAAGCTCCATGAAGAAATTGACAGGGTGATTGGGCCAAGCCGAATCCCTGCCATCAAGGATAGGCAAGAGATGCCCTACATGGATGCTGTGGTGCATGAGATTCAGCGGTTCATCACCCTCGTGCCCTCCAACCTGCCCCATGAAGCAACCCGAGACACCATTTTCAGAGGATACCTCATCCCCAAG
Seq A exon
GTTAAGCAATGAGCCTGCAGCACACAGCATGAACACCATCCTATCAGCTAATCGCCTTCCTGCCAGGGAGCAGGATGGGGGCCCCAAGACCCTTCCCTTTGGCAGGGGTCACTGAGGGGAAGGGCTGGCCCCACTCCCACCCTGTGGGATACTGCATCTCCAGGAGTGCTCACATTGGCCTGGTGACCAGAGAGGTGGAGGAAATCTGGAAAAGAGCCTCAGCAGATAGTGCCTGGGACTGTAGTGAATTCTAATGCCAGGAACAAACTATCACAACCAGCCCTGGGGTTAATCCTGTGAGAAGATTAGGGCTTTCATCTTCATTTAGACCTGACCCCTGACTGCTTTCTATCTAATCCTTCACTAAGCAACTCCTTCAACTGGAAATATACTATCCTATATAGCATAATATTCAAAACTACATTCTTCACTGGGGGTTTCCAGATGAAAGCCCACATTTTGTTAACATGACTCACTGAGACAGTCTTTGTTTCTCCTAG
Seq C2 exon
GGCACAGTCGTAGTGCCAACTCTGGACTCTGTTTTGTATGACAACCAAGAATTTCCTGATCCAGAAAAGTTTAAGCCAGAACACTTCCTGAATGAAAATGGAAAGTTCAAGTACAGTGACTATTTCAAGCCATTTTCCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130649:ENST00000463117:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.042
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(13.6=100)
A:
NA
C2:
PF0006717=p450=FE(10.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTCCATGAAGAAATTGACAGGG
R:
TGTGGAAAATGGCTTGAAATAGTCAC
Band lengths:
326-826
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development