HsaINT0044448 @ hg19
Intron Retention
Gene
ENSG00000142973 | CYP4B1
Description
cytochrome P450, family 4, subfamily B, polypeptide 1 [Source:HGNC Symbol;Acc:2644]
Coordinates
chr1:47279154-47279735:+
Coord C1 exon
chr1:47279154-47279278
Coord A exon
chr1:47279279-47279580
Coord C2 exon
chr1:47279581-47279735
Length
302 bp
Sequences
Splice sites
5' ss Seq
CAGGTCAGG
5' ss Score
7.2
3' ss Seq
TCCTCCTACCCTCTGCTTAGCAG
3' ss Score
4.94
Exon sequences
Seq C1 exon
GACAAGTGGGAAGAGAAAGCTCGGGAGGGTAAGTCCTTTGACATCTTCTGCGATGTGGGTCACATGGCGCTGAACACACTCATGAAGTGCACCTTTGGAAGAGGAGACACCGGCCTGGGCCACAG
Seq A exon
GTCAGGAGCCACCTCGGGGCTGACCGCACTGTCTCCAAAGCCATCTTAGAGGGGAGAGTTGGCAGGGGTCCTGGGCTCTGATCTGAGAAGAGATAGGGTCCTGCCCCAGGGAGCCTTAGCTTGCGGGGAGACAGGACCTGCTCATGGTGGGGTAAACACCTGGCTTTAGCAAGGAGGCTTAAGGGCAGGGAGAAGAAGAGCAGGATGCTCTGTGGTTGGGGCTAGATTCCTGGAATGGAGTTTCTCTGGCTCTGCTCCTGGGCCAGTGTCTAAGCCAATCCCTCCTCCTACCCTCTGCTTAG
Seq C2 exon
CAGGGACAGCAGCTACTACCTTGCAGTCAGCGATCTCACTCTGTTGATGCAGCAGCGCCTTGTGTCCTTCCAGTACCATAATGACTTCATCTACTGGCTCACCCCACATGGCCGCCGCTTCCTGCGGGCCTGCCAGGTGGCCCATGACCATACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000142973-CYP4B1:NM_001099772:5
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.033
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(12.1=100)
A:
NA
C2:
PF0006717=p450=PD(36.2=89.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGTGGGAAGAGAAAGCTCGG
R:
CTGTATGGTCATGGGCCACCT
Band lengths:
278-580
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)