HsaINT0046685 @ hg19
Intron Retention
Gene
ENSG00000119522 | DENND1A
Description
DENN/MADD domain containing 1A [Source:HGNC Symbol;Acc:29324]
Coordinates
chr9:126141933-126146192:-
Coord C1 exon
chr9:126145934-126146192
Coord A exon
chr9:126144905-126145933
Coord C2 exon
chr9:126141933-126144904
Length
1029 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGG
5' ss Score
9.99
3' ss Seq
CCCTCCTTCCCTCCCAACAGAGG
3' ss Score
11.43
Exon sequences
Seq C1 exon
GCCGCAGCCGTATCGGACACTCAGGGAGTCAGACAGCGCGGAAGGCGACGAGGCAGAGAGTCCAGAGCAGCAAGTGCGGAAGTCCACAGGCCCTGTCCCAGCTCCCCCTGACCGGGCTGCCAGCATCGACCTTCTGGAAGACGTCTTCAGCAACCTGGACATGGAGGCCGCACTGCAGCCACTGGGCCAGGCCAAGAGCTTAGAGGACCTTCGTGCCCCCAAAGACCTGAGGGAGCAGCCAGGGACCTTTGACTATCAG
Seq A exon
GTATGGCATGGGCAAGGGAGGGTATCGGCCGGGGGCCGGCACTGTCCGCACACGAGGTGGGATCCCCATGTGACAGTGGAAGAGACTAAGGGAGAAACAGTGACTTTCCAAGACCCTCAGCCAATGCTCAGGGTCAGTGTGACTGTAAACACCTCCCAGGGTGCCGGGGCCCACACCACCCTAACAGTGACGGTAGGAGAAGATGCTAGAGCCCGATGGAAACTTGCCCCACTCTGTGTGTGCATCAGACGGGGGGGCGGGTGCTGCCAGCCACTCTCCTCGCACCCCCAGGCAGGGCTGCAGCCCCTGCTGGAACCGGGATTGCGTCCATCCCTGCCAGGGCTCCTTGGCAGAGCCTGTGGATGCAAGTTCTTGGCTCTGCATTATGAATGCAAATCAGTGTGTAATTCCCACTGTGACGTCTAATCCATCACATCCCCGCTCGGTGCCTCAGTTTCCTCACTTGCAAGTGGGGTCTTCTGACTTTGCATCACTGGGTCACACCGTGGGGTTCACAGAGCTCCAGTCATTCATGAGTGTTCCCTGCTGGGAACGAGGACCTGGGCCAGGAGAAAGGGACTGGCACCCGGGCCGTGTGGCTTGCAAGTGGCAGAGCCAGGACTCCAACTTGGCCTCCTCCTTCCTCCCCAGCCAAGGTGCCTCCTACCAGGCCCTGAGTCTCACTCGCGCCCCCGGGCTTACAGGTGATTGCGGGTGCCTGCGATCTAAAAAGTAAAAAGGGCCAGCCGGTAGCTGGAGTCACTTTCCTAAAACTCCTTGGCAACCGCCACTGGCATAAAGGGACGAGAGCTTTGTCTTGAGTTCCCGGAGCACAGGCTTGGAGTCCCAGCACACGTGGGTCCTCTGCTGGTAACCTGGGGGAGCCCTCAGCTGTTCCAAGTCCGAGGAGCTGATCAGCCACACAACTAGGCCCAGCACACATTCAGCACACAGAAGTGGTGTGGGAATGGGCACACATATGTCCCAACTCAGCCCGTGGTCACTGCCGCCCTCCTTCCCTCCCAACAG
Seq C2 exon
AGGCTGGATCTGGGCGGGAGTGAGAGGAGCCGCGGGGTGACAGTGGCCTTGAAGCTTACCCACCCGTACAACAAGCTCTGGAGCCTGGGCCAGGACGACATGGCCATCCCCAGCAAGCCCCCAGCTGCCTCCCCTGAGAAGCCCTCAGCCCTGCTCGGAAACTCCCTGGCCCTGCCTCGAAGGCCCCAGAACCGGGACAGCATCCTGAACCCCAGTGACAAGGAGGAGGTGCCCACCCCTACTCTGGGCAGCATCACCATCCCCCGGCCCCAAGGCAGGAAGACCCCAGAGCTGGGCATCGTGCCTCCACCGCCCATTCCCCGCCCGGCCAAGCTCCAGGCTGCCGGCGCCGCACTTGGTGACGTCTCAGAGCGGCTGCAGACGGATCGGGACAGGCGAGCTGCCCTGAGTCCAGGGCTCCTGCCTGGTGTTGTCCCCCAAGGCCCCACTGAACTGCTCCAGCCGCTCAGCCCTGGCCCCGGGGCTGCAGGCACGAGCAGTGACGCCCTGCTCGCCCTCCTGGACCCGCTCAGCACAGCCTGGTCAGGCAGCACCCTCCCGTCACGCCCCGCCACCCCGAATGTAGCCACCCCATTCACCCCCCAATTCAGCTTCCCCCCTGCAGGGACACCCACCCCATTCCCACAGCCACCACTCAACCCCTTTGTCCCATCCATGCCAGCAGCCCCACCCACCCTGCCCCTGGTCTCCACACCAGCCGGGCCTTTCGGGGCCCCTCCAGCTTCCCTGGGGCCGGCTTTTGCGTCCGGCCTCCTGCTGTCCAGTGCTGGCTTCTGTGCCCCTCACAGGTCTCAGCCCAACCTCTCCGCCCTCTCCATGCCCAACCTCTTTGGCCAGATGCCCATGGGCACCCACACGAGCCCCCTACAGCCGCTGGGTCCCCCAGCAGTTGCCCCGTCGAGGATCCGAACGTTGCCCCTGGCCCGCTCAAGTGCCAGGGCTGCTGAGACCAAGCAGGGGCTGGCCCTGAGGCCTGGAGACCCCCCGCTTCTGCCTCCCAGGCCCCCTCAAGGCCTGGAGCCAACACTGCAGCCCTCTGCTCCTCAACAGGCCAGAGACCCCTTTGAGGATTTGTTACAGAAAACCAAGCAAGACGTGAGCCCGAGTCCGGCCCTGGCCCCGGCCCCAGACTCGGTGGAGCAGCTCAGGAAGCAGTGGGAGACCTTCGAGTGAGCCGGGCCCTGAGGGTGGGGGATGCACCGAGGCCCGAGGGTCCGTCCACTGCTGCGGTTCCGAGGCTCCCCCGCCACTCTCTCTCTGCCCAGGTTCTGCTGGTGGGAAGGGATGGGACCCCTCTCTGCTGCCCCCTCCTCCCCTCCACACTGCCCATCTCTGATGTCTGGCCCTGGGGAATGGCACCAGTTCCAGCCTGGGAATCAACCCAGTTCCTGAGTGCCCATCCCACCCCGCGGTTGCCTCTCCTCGGCACCCTTGATTGGGTTTTGCACTAAAGAGGTCAGCTGGGCCAATGATATTGCTCCAGACCGAGTCCTACCCACCTTCCCCCGGAAGTGTCCCAAGAGGCTCCGAAGGCCTCCCCTCCGAGCCCAGCTCTCCTGTCTCCTCCACAGCCAGGCCCTGCACGCCCACCTCCTCGGACACAGGTGACAGGGTTACCCTCCAGTTTGAGCTCATCTGCACGAGACACAGGTAGCTTGGGGTTGAAGTTAGGACTCCTCCTGGGCTGGAGGATTTACCTGGTGGGGCACTTCCAGACTGTTTCTAGCAATATACACACACGTTCTTTCCTGTGTCTTCACCCCAAAACTTCAGTTGATTCTGACCTGGGAGGATCTGGGGACCAGGGGGTCTTGGGCTGCCTTGTGATACACAGCCCCAGCCACCCTGCACGGGGGCTGCGAGCACCAGCAACTTTGATTTATAGAAGGAAAATGGAAACCCCCATCTGAGTATTTTGGGAGGAGCCCCCAGCCCTCATCCAGCTCTGGCACGCTGATACCTCCAGGTACTCCCCTCACTGTCAAAGCTGGGGCTCAGCCTCTTGTCATCTGGAGCTTTGTGGGCAAAGCTGAGAAGCTGCAACCCAGATTTCAACCCAAAAAGGTCAAGCTGAATGCCTCAGACTGATGTGGAAGGCAGCTGGCCTTCCTGGGTTGGAACGAGGCAGTGGCCCTGAGCCCCTTCTCCAGGGCCAGGTAGAAAGGACAAACTTGGTCTCTGCCTCGGGGAAGCAGGAGGAGGGCTAGAAGCCAGTCCCTCCCCACCTGCCCAGAGCTCCAGGCCAGCACAGAAATTCCTGAGGCCAACGTCACCAAAGTTAGATTGAATGTTTATTATCTTTCTTTTTCCTTTTTACCTTATTGATTTGATGAATCTTGAAATGGATTCATTTCCATAAACCAAGTTAAAGTATGGCCCGACCATTTAAGAAAACAACCATCTGAGACACGCAGGAAATTGTGAGCATTTCGACCCGAGCTCTCATTTCCTATTTGTGAAGGGTCAGACACAGTCTACCCAGGGGTGTCTGGGGGACAAGGGGGTCTCTGGAGATGTCACCCAGGGAGCCCCCTCTATGTCTGAGAGGCTGCCACTGCTGCACATGCTCAGTGAGGCTTGGCGGCCATCCTGGCACATGGCTCTTCCTGGGTCAACCGTGACCTGTCTGGCTCAGGAATGGGCTCTGGCTGCTGGGGGAGCCGTGTCACTCCTGGGCCATGGGGGCACCTCCTGGGCACTTAGGTGTTTCAGCATAGATTCCAGTTTCGCACCCTGGGCAGACCCCCAGGCCCCATCCGGGATAGGGCAGAGGAGGTGCTGGCGGCCCCAGGGAAGGAGGGTGTGTACCCCAAGGCCCCCTGGCTGTGCTGAGGGGCTGGGGTGAGCGCTCCATGTTCACATGAGCACTGCTGCCTCTTCACTTGTGGGACTTTTTGCAAACCCAAGGATGAACTTTGTGTGCATTCAATAAAATCATCTTGGGGAAGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119522-DENND1A:NM_020946:21
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.891 A=NA C2=0.884
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGTCTTCAGCAACCTGGAC
R:
TCCTCCTTGTCACTGGGGTTC
Band lengths:
347-1376
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)