HsaINT0046695 @ hg19
Intron Retention
Gene
ENSG00000213047 | DENND1B
Description
DENN/MADD domain containing 1B [Source:HGNC Symbol;Acc:28404]
Coordinates
chr1:197510089-197515120:-
Coord C1 exon
chr1:197515052-197515120
Coord A exon
chr1:197510146-197515051
Coord C2 exon
chr1:197510089-197510145
Length
4906 bp
Sequences
Splice sites
5' ss Seq
TTTGTAAGT
5' ss Score
7.4
3' ss Seq
CATTCATTATCATTTTCTAGGCA
3' ss Score
8.37
Exon sequences
Seq C1 exon
AAAGGAGGTGCACTGTTCAACACAGCAATGACCAAAGCAACCCCTGCTGTACGGACAGCATATAAATTT
Seq A exon
GTAAGTTTTTTTGATATTTAACAATCCTATTTATGAAATTATAAAACATTTTCCTAGGTGATAGACATATAAATTCTGAATATTTTCTATTTTTCTTTTAAATAAACCTAAAAAAAAATTAGGATTAATATTGACCAAAGCAAATTCAATTGTTAAAATTATAACATTGCATGCAGAGGGTAGTTTCTTTTATATAATCTAAAAATGGTTCTCATTTTATTCCAAAGCTATCGGCAAAGTTGTGCAGCAAATTGAAACAGTTATTGATGGGGTACCATTTTGTAAAATGTCATTATTTCATTTAACAACATTTTACATTCTTGCTGTGTACTTGCGGCTCAAGTAGAAAAAAAAAAAGAAAAATATAGCGAGGTCTTTTCCCTCAAAGATGCATTGACTGTTTATTAACATTCTTCAGTGAGTCTCCAAGGCAAGTTTGTCCAACCCATGGCCTGTGGGCTGCATGTGACCTAGGATAGCTTTGAATGTGGCCCAACACAAATTCTTTTTTTTTTTTGAGACGAAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGTAACCTCCGCCTTCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACCCACCACCATGCCTGGCTAATTTTTGTATTCTTAGTAGAAACGGGGTTTCATCATGTTGGCCAGGCTGGTCTCAAACCCCTGACCTCAAGTGATCTGCCCGCCTTGGCCTCTCAAAGTGCTGGGATTATAGGTGTGAGCCACTGCGCCCAGCCCCAACAGAAATTCTTAAACTTTCTTAAAACATTCCAAGATTTTTCTTGGAATTCTTCTTCTTCTTCTTCTTCTCCTTCTCCTTCTCCTTCTCCTCCTTCTTTCGTCGTCGTCGTCGTCGTCTTCCTTCTTCCTTCTTCCCCTTCCTCCTTCCTCCTTCTCCTTCTCCCTTCTCTCTTCTCCCTTCTTCTTCTTCTCTTTTCTTCTTCTTTTCTTCTTCTTTCTTCTTCTTCTTCCTCTTCCTCTTCATCTCCTTCTCCTCCTTCCTCTTCTTCCTCTTCTTCCTCCTCTTCCTCTTCTTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCTTCTTCTTCTTCCTCCTCCTCGTCCTCTTCCTCTTCTTCTTTCTCCTCCTCTTCCTCCTCCTCTTCCTCTTCTTCCTCTTCCTCTTCATCTTCATCTTCTTCTTTCCTTTTCTTTTTTAGCTTATCAGCTTGTGTTAATGTTAGTGTATTTTATGTGTGGCCCAAGACAATTCTTCTTTCTCTAATGTGGCCCAAGGAAGCCAAAAGGTTGGACACCGCTGCTGTAAGACTTGCAGAAAAAAAATAATGGGAATAATAGTAAGAATAATAAAGTAAATAATAAATGATAAAGTAAAAAAACTCTTTAATATGACAATTAAGACCCTTCAAAACCCAACCCTTCATGTCTAGTTCCTTTTCCCCCTACTCCTCAGAACGTTCCATATCTCTGAAGACACTTAGCTACTCCTCATTTCATGAATGTGAGATATTCTCCTCTGCCCTTTGATTCTTGCTCAAGCCATTCCTATTAATTGGAATGTCAGTTTCTTGGCCTTTATCCACCTAGTCAACACCAGTTCATTTTACAGGACTTAGTTCAGACATTATTTCCCCTGAAAAAATTTTTCTGAACCGTACACAAAAAAAGCTTTTATACATATTTTTGTCTTCTCAACCCTACACAAAAATGTTTATATACGTATTTTTGTATCTGTAGGACCTTCTGTTTCAACACTTGTTTTGTCTGTGTACATTTCTCTCTCAATACTAGTCTAGTAACTTCCCAGGAGAGAAGCTAGTGTGTTGTGTTCAATAAATTTTTTAAAATTCAATAGGTCGGATATTTTATATTTCTAAAAATATTTAAGGCAAGGGTTTTGATTTTGTAAGAATTTGTCTTCAAAAGCTTTTCTCGGTAAGTGAGTTGATGTGATTGAATTAATAATAAAATAGTATATTTTAATAAAAGTTTAGAACTTCTGTTATTCCTTGAGTTAAAATTGTGATATGAATGTGGCCACCCTTTCTGTTTAAAAATTCCATTCAAATATTAAATTTTATAGTAGGGAAGCTAATCTATAGAGTTGATTAAAAAATACAGTCCCAAAATTAGAATTATTTGATCCCTAACCATAAGGCCAAAATAAGACAAGGTTATCATTTTCCCTTAGAAACCTCAGCCTCTGCGTTTTTTTTGGTTGTTCTATGGCTTTCCTAGGAAACCTCTCTGGTGGTTTAAGTGCAGTTTTTGAAGAGATTTTTTTTTACAATGAAATAGTACACAACTACCATGTGAAAAAGCAAAGTAATGTTGATCCTTGTTTCTCACATTCATTTAAGATTCTAAAAATGGTTTCACAGTCAATAGCCCTTCATTTTCTTCTGGAGCAGGCAGTTGAGGGTTTTTTTTAGGCTTAGAGAAGTTGTATTGTTTTGCCAAATATGTGTCTTGCCTTAATTTCACTCATATTTTTCACAAAAGCGCAGCAATGAAGCAAACATGTTCAAAACCCTATTCATTATTTTAAAATTTATCATTCTAATCAGTGGAGTATTTTATTTTGAACTCTTCTCTGCAAGGAAGTAAAATCTTTTCAAATTAAAAATTCTATTCTTTGGGCCGGGTGCTGTGGCTCACACCTGTAATCCCAGCACCTGGGAAGCCAAGGCAGGTGGATCGCTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTATTGAAAATACAAAAATTATCCAGGTGTGGTGTCGTGCTCCTATGGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTGGAGCCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATTGTGCCACTGCACTCCAGCCTGGGCCACAAAGTGAGACTTTGTCTCAGGGAAAAAAATAAATAAATAAATAAATAAATAAAAAAGGTTTCTACTCTGGAGGATTGTTCCCTAAATTAATTTCAGGTGAATTAAGATCTTTAGAATATACCTAATCACTTTTTTATCATTTATCTTGTGATCATATCATCCCTGAATCAGGAGGTTTGGGGCAGGTAAGTCAGTCATTCTGTGATCTTTGTAATTGTTTCTAAAACTGATCTTTCCAGACTGCTCATTTTCTGAAATGTGTACTCTGAAATTCCTTCTTTGACCACAAATTGCTATGAATAAAACTCCTAATTTCTGTTGTGTGGTATAACAGAATTTACTTACCTTGGTTTTCTATAGATAGTAAATTTTTCAAAAGTAGGAATCATGTTTTTACCTCTATCTCATTTATTCAATAAATTATTTGAGTGCCTATCGTGAACTAGGCCTTATACTCATCATTGGAGTTATAGCAGAACATGAAGGTACAGTAAGAGATACTGTCCCTACTTTTATATTTGTTTTCCTATCACTTTGCTCTGCACTTTGAACATACTACAGAAATACTGAATATGTGTTTGTCAAAGCAAATAATGATTCCATCCTGTTCTTATAACATTTTTATACTTATTTTTATAGTTAAAATTTTTTTTCCTATGCTTTTCATGCATATGTTTTTCTATGCTGATAGGGGCCATAAAGAAAACTAGAGTTATCATACACACTTGTATAAATTTAAGAATAACAGCAAAGTGGAATTCATATTTTATTTGGCTAAACGGTTTTCAGAGTCATCTTTCTTGTTAGGTCTCCATTTTAAATTATTACCAAAGCCATTTGCTTGGAGCATTTCTCTGGAGAATACTTGCATTGTGTTAAGCTTCAAATTGGTAAGTTGAAAAGGATAGAGAGAACCTATATCCGGCCTTCCAGGTTATCTGAAGGAAGTCAGAGGAGGACATGGGACAACAATTATTTTAATGAATCAGTGCACTATGGAATTATAGAACCATGGAAGAGACTGACACTAGTAGCTTCAACTCTGTATACTAAAGAGCATCTGAAAAGATTAGTGTGATCAAGTGGATTCGAGGATAGTTAGCTAGATTACAGTCTCCCTGAGTCACTTTCCTTATTTTAAAATGTGATCATAGTAGTACTAATCTTACAGAATTGTTGTGATAACTACCTAAGATAATGCATGCTAAGCACCCAGCACACAGTCATATATTTAGGAAACAAAATAAATATGAATTCCTTTTCTCCTCTTTTTCACCTTTGCCACTGTGAGTAGGAATTTCTAGTGGAACAAAGGCTAAGGCTTTTGTGAAAGCCCCCAGTTGTCTTTAGTTAAGTTATACCCCACAGGAATCACAGCAGGATGTGAGAAACTCAAATGCTGGGGCCAGGTTCCCTGTGAAACATGAGGATAGCTTTAAATTGTTAAATGACTTTTAAGTTTTACCAGAAAAACTATATATGAAATACCATTCCATTAAGATGGCTCTGCTAATAAAATTCTGTGTCTGCCTGTAAAAGCTCTTAATAAAGCTTTGTAAAATTGCCAAAGTTTTTTCAAGTTCAAGCATCTACCCAAATAATTTGCTGCGGGGATGTACTTTCTCTGTTCCTCCAGTTTGTTACAGTTTTAACATTGTAATCTGGTTTATTCCTTTTGTGTTCTTTATAGTTTAGGAAACAAAATAGTCTAAATGTTAGCCTTTGTATGATACTTGTATACAAAGAAGAGACTAATGGTTTTACCAACTGATTTAGGTGTAATAAAATAGTAAGTGATATGCGTATCCCTGAAAATAGAATGTTAGATTATAATCTGTTCTTTTTCTAAATCATATGAATATTTAGTAATTGTCATTAAATTTGATCTTGTATACTTATTCTTTAAATGGTAATGGAACCATCCTGAGCCAGGCACATTCATTATCATTTTCTAG
Seq C2 exon
GCAAAAAATCATGCAAAGCTGGGACTAAAGGAAGTGAAGAGTAAACTAAAACACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000213047-DENND1B:NM_001195215:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=NA C2=0.158
Domain overlap (PFAM):
C1:
PF0345514=dDENN=PD(6.7=27.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)