HsaINT0049270 @ hg19
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein, axonemal, heavy chain 10 [Source:HGNC Symbol;Acc:2941]
Coordinates
chr12:124398876-124399546:+
Coord C1 exon
chr12:124398876-124399097
Coord A exon
chr12:124399098-124399398
Coord C2 exon
chr12:124399399-124399546
Length
301 bp
Sequences
Splice sites
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
3' ss Seq
CCAATGGCTGTTTCTTCCAGATG
3' ss Score
8.14
Exon sequences
Seq C1 exon
GTGGCTGAACGACCTGGATGAGCTGATGCACCGGCGCGTGAAGCTGCTGGGGGACTGCCTGCTCTGCGCGGCTTTCCTCAGCTACGAGGGAGCCTTCACCTGGGAGTTCCGTGACGAGATGGTCAATCGGATTTGGCAAAATGACATCCTGGAGCGGGAGATCCCCCTGAGCCAGCCTTTCCGGCTGGAAAGCCTGCTCACGGATGATGTTGAGATCAGCAG
Seq A exon
GTGTGTGGCACCCTGAGCCAGCAGGAGGGAGGGGACACCTTAGCACAGGGGGTCTACGTGGGTGTCACCCTGGGGGGAGGCAATGGCCTGGGGGGCATCACCAGGACCACAGTTGGCTCGACTGCATGGAAGTGGCCGGGCAAGCTGCAAACCCAGCACGGAGCCCTTCTCCCTGGCCTCTGAGGAGGCTTGTGTGGCCTGGGGATGGGTAGATTGTTCTGGAAGGCCAGTCCTACCACCCTTAGCCCTTGGCTCACAAATTGGTGAGAAAAATTCATTTCCCAATGGCTGTTTCTTCCAG
Seq C2 exon
ATGGGGATCCCAGGGCCTTCCCCCCGATGAGCTCTCCGTTCAGAATGGCATCCTCACCACCCGGGCCAGCCGCTTCCCTCTGTGTATCGACCCCCAGCAGCAGGCCCTCAACTGGATCAAGAGAAAAGAGGAGAAGAACAATCTGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653-DNAH10:NM_207437:60
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=PD(14.5=65.3),PF127812=AAA_9=PU(3.9=12.0)
A:
NA
C2:
PF127812=AAA_9=FE(21.2=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGCTGAACGACCTGGATG
R:
TCTTGATCCAGTTGAGGGCCT
Band lengths:
344-645
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)