HsaINT0049270 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123914329-123914999:+
Coord C1 exon
chr12:123914329-123914550
Coord A exon
chr12:123914551-123914851
Coord C2 exon
chr12:123914852-123914999
Length
301 bp
Sequences
Splice sites
5' ss Seq
CAGGTGTGT
5' ss Score
6.99
3' ss Seq
CCAATGGCTGTTTCTTCCAGATG
3' ss Score
8.14
Exon sequences
Seq C1 exon
GTGGCTGAACGACCTGGATGAGCTGATGCACCGGCGCGTGAAGCTGCTGGGGGACTGCCTGCTCTGCGCGGCTTTCCTCAGCTACGAGGGAGCCTTCACCTGGGAGTTCCGTGACGAGATGGTCAATCGGATTTGGCAAAATGACATCCTGGAGCGGGAGATCCCCCTGAGCCAGCCTTTCCGGCTGGAAAGCCTGCTCACGGATGATGTTGAGATCAGCAG
Seq A exon
GTGTGTGGCACCCTGAGCCAGCAGGAGGGAGGGGACACCTTAGCACAGGGGGTCTACGTGGGTGTCACCCTGGGGGGAGGCAATGGCCTGGGGGGCATCACCAGGACCACAGTTGGCTCGACTGCATGGAAGTGGCCGGGCAAGCTGCAAACCCAGCACGGAGCCCTTCTCCCTGGCCTCTGAGGAGGCTTGTGTGGCCTGGGGATGGGTAGATTGTTCTGGAAGGCCAGTCCTACCACCCTTAGCCCTTGGCTCACAAATTGGTGAGAAAAATTCATTTCCCAATGGCTGTTTCTTCCAG
Seq C2 exon
ATGGGGATCCCAGGGCCTTCCCCCCGATGAGCTCTCCGTTCAGAATGGCATCCTCACCACCCGGGCCAGCCGCTTCCCTCTGTGTATCGACCCCCAGCAGCAGGCCCTCAACTGGATCAAGAGAAAAGAGGAGAAGAACAATCTGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:60
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=PD(14.5=65.3),PF127812=AAA_9=PU(3.9=12.0)
A:
NA
C2:
PF127812=AAA_9=FE(21.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGCTGAACGACCTGGATG
R:
TCTTGATCCAGTTGAGGGCCT
Band lengths:
344-645
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development