HsaINT0049271 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123914852-123916736:+
Coord C1 exon
chr12:123914852-123914999
Coord A exon
chr12:123915000-123916456
Coord C2 exon
chr12:123916457-123916736
Length
1457 bp
Sequences
Splice sites
5' ss Seq
CGGGTATGG
5' ss Score
8.17
3' ss Seq
CTGCCTCCCTTCTCTTCCAGGTC
3' ss Score
14.16
Exon sequences
Seq C1 exon
ATGGGGATCCCAGGGCCTTCCCCCCGATGAGCTCTCCGTTCAGAATGGCATCCTCACCACCCGGGCCAGCCGCTTCCCTCTGTGTATCGACCCCCAGCAGCAGGCCCTCAACTGGATCAAGAGAAAAGAGGAGAAGAACAATCTGCGG
Seq A exon
GTATGGTGGCTCCTCCCAGGGCGTCTTCTGCCCCCTATTCCTGTTCTCTGGAGAATGCCCCTCCCGCCTCCTGTACGTGGCAGTCCCTAGCCTCAGCGAGGCTGGGCTGAAATGCTTCCATCCTGACCCCCATGCGGAGCCCTCCCCCGGCTCCGCCTCCGCCTCCACCCCGTGGGTCTGCCAGGGCAGCTCAAACCGCCATGAACTCTGCCTCTCCCCTCGCAGGCTGTGAGCAACCTTAGCTTCGTGTTCCTCTGTCCAGTACGGGGTTCGTGGTCTGGGTGCTCAGTCACTATTTTTTGGAGCTGAGGTGGGGGATGGGGATGCAGGGGAGGAGAGGGGAGAGTAATGGCTTGATTGAGATGTAATTCACATACCACACCTTTCCCCCACTGAAAACATACAATTCAGTTTGAGTTTTAGTATATTTACAGAGTTGTATACCAATCACCAGAGTCAGTCTTAGAACATTTTTATTATCCCTGGAAGAAATGCTACATCCTTTAGCCATCACCCCTCCAGTCCTTCCGTTTCTCCCTCCCCGAGCCCCTGGCAGCCACTCATCTGCTTTCCGTCTGTGAATGTGCCTCCTCTGGACATTTCTTAGGAATGGACTCAGACGCTGTGTGGCCTTTTGTGTCTGGCGCCTTTCACTCAGCCTGATGTTTTCAAGGTCCGTCCTTGCTGTAGTGCATCAGGGCGTCATTCCTTCCTTGGGCTGAATGATATTCCGGTGTATGAACAGACACATTGTGTTCATCCATCCATTTGCTGAGGGACAGTTGGGTTGTCCTACTTTTTGGCTGTTTGAAGAATGCCGCTGTGAATGTTGGTGCACACGTTTCTATGTGGCCATGTGTTTTCAGTTCTCTTGGGGCGATACCTAGGAATGGAATTGCCGGGGCGGCCCAATCACTTTTTGCTGAGCTAATGAACAAATTAATTATTTTCAATTTAGCTTTTCCTCATTTTTTTCTGGTCCTTGATCTCAGGTATTTGCCTGCTGTTAGAGGAAGCCCATTTGTACTCCAAGGTCAGGGGAACAGTCTGCCTCCAAAATGCACATGGAGCTATCAGGGAGCAAATACTATGAGGGCAGGAACTTTTCTAGACTCCCTCTTCCCTCAGCCTGCCAGGGAGCACTGAAATTGTCAGCCTACCCCTAGTCCAATTCCAACATCTACCCTCTCTCTTAAAGAGGAGGGGTTCTAGCTTACGGGAGAGGGGCTGAGGAATCCCCTTCCTTTCCTCTCTACCCTGTTTGAGCAAGATCCTGCCCTGAGCCTGGACCTCATGGTGTATATGCGTTATACCCCTTGCTTCTCTCTTCTTTTCACCTCTGGCCCCCTCCAAGTTCCTGGCCCATCCACTTCCCACTTCCAAGCCATTCTCCCCTTATATTTGGCAGGGCCACAGTTAAACGTGGGCTTTCAGCATCTGCCTCCCTTCTCTTCCAG
Seq C2 exon
GTCGCTTCCTTTAATGACCCTGACTTCCTCAAGCAGCTAGAGATGTCCATAAAGTACGGGACCCCTTTCCTGTTCCGCGATGTTGATGAATACATCGATCCTGTGATTGACAACGTCTTAGAAAAAAATATAAAAGTCTCCCAAGGACGGCAGTTTATTATCCTGGGAGACAAGGAAGTGGACTATGATTCAAATTTCAGACTGTACCTGAACACCAAGCTGGCCAATCCCAGATATTCCCCATCCGTGTTTGGGAAAGCTATGGTGATCAATTACACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:61
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127812=AAA_9=FE(21.2=100)
A:
NA
C2:
PF127812=AAA_9=FE(40.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCTCTCCGTTCAGAATGGC
R:
GATTGGCCAGCTTGGTGTTCA
Band lengths:
349-1806
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development