HsaINT0049278 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123926637-123928587:+
Coord C1 exon
chr12:123926637-123926820
Coord A exon
chr12:123926821-123928386
Coord C2 exon
chr12:123928387-123928587
Length
1566 bp
Sequences
Splice sites
5' ss Seq
AAGGTAATT
5' ss Score
8.83
3' ss Seq
TTCCCTCTCCCCCGGCGCAGGTG
3' ss Score
10.15
Exon sequences
Seq C1 exon
GTATGTGCAGCCCCCAATGATCAGCTTTGAAGCTATTTTTGAGCAGAGCACTCCACATTCGCCCATTGTGTTTATCCTGAGTCCTGGCTCCGACCCTGCCACTGATCTTATGAAATTAGCAGAGCGAAGTGGTTTTGGAGGAAATCGCCTCAAATTCCTTGCAATGGGTCAAGGTCAAGAAAAG
Seq A exon
GTAATTTGTGGCTGAAAGGAACAAGCTCTACGTTTAGGGGAGGTCCCTGGTGTCTGCTAAGAAGGAGCTAACCTGGGTTTAAGCTGAGTGCCACGCCACAAATCAGTTGGATGCATTTCCGAGCTAAGAAGCAGTAATGAAACACTGGGAAGATGACAATAATAGTTATGATTTCACAACCTCATGTTGTGATCATGGTGCTGTGCTGTTTTCTTTTTTTTTCCTTTTTCTTTTCTTTTTGAGACAGGGTCTCACTCTGTCACCCAGGCTGGAGTGCAGTGGTGCGAACATAGCTCACTGCAGCCTCGACCTCCTGATTGTGAAGTGATCGTCCTGCCTCAGCCTCCCCAGTAGCAGCTGAGACTACAGGCATGCGTCACCATGCCTGGCTAATTTTTTTGGTATTTTCTGTAGAGAAAAATACAAACACGTCACCATGTTGCCCTGGCTGGTCTTGAACTCCTGGGCTCAAGCGATCCTTCCACTTCGGCCTCCCAAAGTGTTGGGATCACAGGCATGAGACACGATGCTCAGGCTGTGCTGTTTTCAAAGCCCTTTCACACACAGTCCTTACCTTCCTTAGTCCCTGAACAGCCTCATTGTGGATCAGGATTATTATGGCCCCAATTGCATGGCCAAGGGAGTGGGTGGAGAGAGGCTGAGCCCAGGACCATTCAGGACAGAACTGTGGTGCAAATCCTCCTACCTTTCTGAGCCAGTGAGCTTTCTTTGCTGAGGTCTTGCCTCTCTGCATCACAGTGCTCCCTGCTAGAACTTGCTACACAAGTTCAGTACAATGTGGGACAAAGCTTGCAGGAAAAGTCTGTGCGTCAGTAAGTGTGATGGTTGCAGGCATGCGTGTTGGGGTCAGAGGGAGCTGACTGCCAGTCCTGGCTTTGCTATGAACTGTGAGGCTTTGGGTAAGCCCCTCTACTGCTGAAAGCCCCTGGGTGAGATGAGGATGGCAATACCCATGCTGGATGGCCCAGGAGGCAAGCCCTGGGCACCAGCAAGGCGGGCCAGCTCTCTCAACCACAACACTGAAATAAGCTATTGTAACGCCAGCACTCATGTGTTTTAAGCCATTTCAGAAAGCAAGGCTTGATTTGGGTGTTTAGCTTGTTTGTGCTTTGAATTACATTTGGGAGGGGACATGGTGATTGTTTTCCAGGCCTAGGGCCCTGAAGATCTTACAGTGGCCAGGACAGTCCCGACTTCCTGGTGGGCTTTAGCTGGTCTCTTGCAGCCCTGCTCAGGAGTCCTCAGGGGACAGGAGCGACTGTGTGGGAGGAGCTGGGACTTCCAGGGCCAGGGAGGCAGATGAGTGCAAAATGCTCACCCATCTTCCAGGCTGGGTGTGACCAGCTCAGTGCACCCACGGGGCCCATGGGGTTTCTCAAAGATGGTTTATTTGAAGGCTCCACCTGTAGCTCCTGGATCCTCGGCTTGCTTTTGGCTTCTGCTGGAGCTGCCATCGCCCTTCTGTGGGTGTGGAGTGGGTCTCTGGAGAGCACGGGGTTGGGTTTGGATGCCAACCCCTCTCCTCTTCCCTCTCCCCCGGCGCAG
Seq C2 exon
GTGGCCCTGCAGCTGCTGGAGACGGCGGTGGCTCGGGGGCAGTGGCTGATGCTGCAGAACTGCCACCTCCTGGTCAAGTGGCTGAAAGATCTGGAGAAGTCCCTGGAGAGGATCACCAAGCCCCACCCAGACTTCCGCCTGTGGCTCACCACGGACCCCACCAAGGGCTTCCCCATTGGGATTCTGCAGAAGTCCCTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:68
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(8.6=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(9.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAGCAGAGCACTCCACATTC
R:
AGGGACTTCTGCAGAATCCCA
Band lengths:
342-1908
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development