HsaINT0049285 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123931636-123932108:+
Coord C1 exon
chr12:123931636-123931847
Coord A exon
chr12:123931848-123931940
Coord C2 exon
chr12:123931941-123932108
Length
93 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGC
5' ss Score
7.75
3' ss Seq
TTGCTCTTGATTCTAAATAGGCC
3' ss Score
8.58
Exon sequences
Seq C1 exon
GGGAATCCAGCAGTGGTATCAGCCGCGATGATTATATTGGCCAAGTGGCCAAAGAAATAGAAAACAAGATGCCCAAAGTCTTTGACTTGGACCAGGTGAGGAAGCGCCTCGGAACAGGACTCTCCCCCACTTCGGTGGTGCTCCTGCAGGAACTGGAACGCTTCAACAAGCTTGTGGTCCGGATGACGAAGTCTCTGGCTGAACTTCAAAGG
Seq A exon
GTGAGCCTGTCTCTCATGTGCAGATTACTGCCTAGATACGTGGCACCTGGGGTTCTGATAGAGTCCTGCCCGATTGCTCTTGATTCTAAATAG
Seq C2 exon
GCCTTGGCTGGAGAAGTTGGAATGAGCAATGAGTTAGATGATGTGGCCAGGTCTCTTTTTATCGGGCATATCCCTAATATCTGGAGAAGGCTTGCTCCTGACACCTTAAAGTCCCTTGGAAACTGGATGGTCTACTTCCTGCGGCGGTTCAGCCAGTACATGTTGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:74
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.014 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(9.8=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(69.6=100),PF154071=Spo7_2_N=WD(100=78.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGAACTGGAACGCTTCAACA
R:
GTGTCAGGAGCAAGCCTTCTC
Band lengths:
169-262
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development