HsaINT0049320 @ hg19
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein, axonemal, heavy chain 11 [Source:HGNC Symbol;Acc:2942]
Coordinates
chr7:21737693-21742420:+
Coord C1 exon
chr7:21737693-21737831
Coord A exon
chr7:21737832-21742327
Coord C2 exon
chr7:21742328-21742420
Length
4496 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
TAAACCTGTTTTGATTTTAGGAT
3' ss Score
9.6
Exon sequences
Seq C1 exon
ACCCTGTGCCATGGTGGCCCCTGACATTGAGCTAATCTGTGAAATCTTGTTAGTTGCTGAAGGTTTTGTGGATGCGCGTGCATTAGCCCGAAAGTTCATTACGTTGTACACGCTTTGCAAGGAGCTTCTCTCCAAGCAG
Seq A exon
GTGAGGGATCATTTGTTACGTTTTCTTGTTTTTACATACCATTGAAAAAGCTTTTGAAGTATGGATTTTAGGTAATTTATCATTCAAATTACATTAGACATTAAAATTTTTTTGTACTTAAAAAAATTCAATAGTTTGGGGGAACAGGTGTTTTTTGGTTACATGGATAAGTTCTTTAGTGGTAATTTTTGAGATCTTGGTGCACCTGAGGAGTGTACACAGTACCCAGTGTGTAGTCTTTTATCCCTCACCCACCTCCCACCTTTTCTCCCAAGTCCCTGTAGGCCATTATATCATTCTTATGCCTTTGCATCCTCATAGCTTAGCTCCCACTTATAAGTGAGAACATACGATATTTGGCTTTCCATTCCTGAGTTACTTTACTAGAATAATGGTCTCCACCTCCATCCAGGTTGCTGCAAATGCCATTATTTCATGCCTTTTTATGACTGAGTAATATTCCATGGTGTATATATACCACAGTTTCTTTATCCACTCATTGGCTGATGGACATTTAGGCTAGTCCATATTTTTGCAATTGCAAATTGTGCTTCTATAAATAGGCATGTTCAAGTGTCTTTTTCATATAATGACTACTTTTCCTCTGGGCAGATACCCAGTAGTGGGATTGCTAGATCAAATGGAGATTCCTTTAAAAACTAAAACTACCATTTCATTTGACATTAGAAATATTTTTATATTTTCTATAAAATTCGAAAAACTTATTTTATAATTTTTATTTTTTTCTGAAATTTTGAGATATTTTAGTTCTGATATTTTATTTGTATTAATACTTTTTTAAATCAACGAGCTGTGTGATTTTCTTTGTCAATTTTGTAATCATAAATGGAATTTTATGTTGCCTCCCTTTCTTCGTGAAAATATTATTTTCTAATAAGATAGGGCAGGAGTGTTCAAAAGAGTAAGATAAGGCTAATTTTCTGAAGAGTATCTCAAGGAATGTTAAAATTATTCTCATTTATTGGTAATTCTTTATTTAAAGGTAGGGTTGACTGGTTTTTTGTTCTTTTAAATTTGTGCTCTACAATTTCCTTGTCTCTAAAATGGGTCAGATTTACATACTCTCTACTCTCCAATCATAAGCTTCTTGAAGATCTATTGAAGTTGCTGATAAGCCACAGAAATTACATATATATCAGCATCAATATTTTAAAATTCAGCCATATGATCATTTTTGACTTTTGGTCTTTTGATAACATTTCATTAATTACTGGTGACATTATTCTGTAGTCAAAATGAAAGCATCAGAATACCACAGTTGCAACCACACAGTTACCTTACTGCCACGTATTTATTTTAACTTGCTCATTGTTAGGGCAAAATATGGAATATGAGAGTGATTTATGTTGTCCTTTTAGTAACTGTGAATTTACATTGGGTGGGTGGAATCATAATTTTTAACAGTTGTCTCTGGATAGTAAGATTATGGGTGTTTTTATTTTTTTCCTTATTCTTAAAATCTTTTTTTAATGAGCCTATTTTAATTTTATCATGGTAACAAGTCAGAAGAAAAAAATGTAATAGAGCCCAGGGAATGTGGAGTTTCAACTATATCTATTTTCAGTAGTAATATTTAAACATTTAATGAGCATCTAGTATAACTAATAATGTGCTTTTTGCTGACCATGTTGAATGTGTAAGATTCAAAACAAATGAAACAAACACCCAGATTTCTGACTTTGAAGAATTTAGGTAATTCAGTTTACATGACATAAAAATTGGGAGACAATGGAGAATGAAAAGATTATCAGAGTTTTCAAGGAAGAAAGGAACCAATATTTATTGAATGAGTACTATGTGTTATGTTACAAAACTGTCAAAAGAAGTTTACAAATTTGATTTTATTAGCCCTGTTTTACATATGAGAAAACTGAGCAAAACAACCTGTCCCAAGTCCATATAGCTAACAAGGGATAAGGGCAAGATTTGACTTCAGTTCTAATTCTGTCTAGGACACACCTGTAGCCAATTACAAGAGGAAGGTGTTGGGAGTACAGGTAGAACAAAGAAGGAAAGAGTTTGCTAACTCAGAAATGTCACAAATGAGCAAAAAGAAATCTGGCCAGGACAGAAGAGCTGGGTTAGGAACACAATTCAAGGATAACTTCCTGTGCTACAGAAATGGGTTTGGGAAAAGAATCAGCAGACATTTTTGACCATTGGAATGATATAATGAAAATGGTGAAGATACTTTTAGCTATTTGCATTGTTTAAATGTTTAGCAGAGGCACCAAGTCCTCTGAAATCTGTGGTCCAAAATTTCTTCTGCATCCACTCCTTTTATTGTTACTGCAATAACTTAGCCACCTCCCATTGTTGCCCTCAAAGTTCTTATTCTCAGAAACACCATTTGACCCAGCAATCCCCTTTCTAGGTATATACCCAAAGAATTATAAATCATTCTACTATAAAGACACATGCACACATATGTTTACTGCAGCACTATTTACAGTAGCAAAGACTTGGAACCAACCCAAATGGCCATCAATGATAGACTGGATCAAGAAAATATGGTACATATACACCATGGAATACTATGCAGCCATGAAAAAGGATGAGTTCATGTCCTTTGCAGAGACATGGACGAGGATGGAAACCATAATTCTCAGCAAACTAATACAGGAATAAGAAACCAAACACCACATATTCTCACTCATAAGTAGGAGTTGAACAGTGAGAACATATGGGCACAAGGAGGGGAACATCACACACTGGAGCCTGTTGGGGGTGGAGGGCTAGGGGAGGGATAGCATTAGAAGAAATACCTAATGTAGATAACAGGTTGATGGGTACAGCAAACCACCATGGTACGTGTATACCTATGTAACAAATGTGCACATTCTGCACATGTGTCCCGAAACTTAAACAACAACAACAACAACAACAAAACCTCTGGTTCTTTCCCCTCCCTTTCCTCTTCAAGCCTCAGCCTACTCCATCAGTGGCTTTCAAATGATCTTTTCCATGGCCCACAGTAAAAAATAATTCTTCTATTGTGACTCAGTGCATACACACATGTACAACTGAACCAAAAATTTCACCAAACACTTTTTACTTTTTTTTTTTTTTTTTTGAGACAGTGCCTCGCTTTGTTACCCAGGCTGGAGTACAGTAATGTGATCATAGCTCACCACAGCCTCGACCTTCCTGGCTCAAGCGATCTTTCCATCTCAGCCTCCTAAGTAAATGAGACTCTAGGCGTGCACCATCACGCCCAGCTAATTTTTGTATTTTTTGCAGGAGTGGGGTTTCCCCCTGTTGCCCAGGCTGGTCTGGAACTCCTGGGCTGAAGCAATCTGCCCGCCTCAGCCTTCCAAAGTGCTGAGATGACAGGCATGAGCCACCACACTCAGCCACTTTTTGCTCTCATTTGCATCACACTGCAGTGTTTTTCATTTCGTTCCCTTTTATTACAGACAAAAATGATGGTCGAGACCTACTAAATTGATTTTATTATCCACTAGTGGAGTAAATGGGATATTTGTAATGTAATATTGTTTTACCGCCCACAAAAAATTTGTACTCATATTAATTCACTTTACTCCTACAACCACTTATAAAGTAGGTGGGTGCTTTTATCTCCCTTTTTATAGATGATGATTCTGAGGCTCTGGGAGGTAAAGTGTCTTTCCCATAGACACAGCTGAGAGACATTTGAGAGATGGGTTGTTACTGTGTGGGTTGTAGCTGGACGGTGAAAGAGGGCCAGTCCCGTGTAAGCAGTTAGTTCGTTAGGAATACCTTTACTGAGCACCGTGCAATGTGCTAGCCCCAAGAAGACAGTGAATATATGGGAAATAAGTTTATCATGAGAAAAAGCCAGAAGAAAAAATGTAATTGGTCCCAGGGAGCATGGAGTTGCAATTGTATCCAATCTCAGAAGTAATATTCTGAGATCCTCTAAGAGCTCAGACCCTGTGGGAGGAGTCTTCATTAGGGATAACGTTGTAGTCTCAAAAACAGATAATTGAATTTTAATGACATGGTTTTTATTATATTATGTGCTGGCATCTAGGCAGAAGTATCTGATTAAGAGGTGGAGTAATTGGGGCCATTAGGGATCCAAGTCTGGGGAGAAGTAGAATACCAGGGCCCTTGATGAAACCAGCACAGGTGGAGAAATGTGCTTCTGGTTGGAGGTGAAAACGGGGAATTTGCTGAGCTACTGAGTTAGCAGGTCTGTTGAGAGAGTACAGCAAGGGAGGTGGATGGAGCCTTAGGCAAATACTGCAGTTAAGCGCTATGGAAAGAAGAGACTTGCTGACAGAGGCAAAAAAAAAAAGGTGAAAGAAACAGGACGACACTACAGGGACATGATTTTCACAGTTTCAAAGAGCAGAAGAAAATAGTATTTTGAATCATTAAAGTGTGTATTTATCTGAACTCCTTCTTAAAAACTTTCAGCTCTTACCTCTGGAATGAGAATCTTCTTCCCTCATACAATTTTTGAGAAAATAAACCTGTTTTGATTTTAG
Seq C2 exon
GATCATTACGACTGGGGACTTCGTGCTATTAAGTCTGTCTTGGTTGTGGCTGGATCTCTGAAACGAGGAGATAAAAATAGACCCGAAGATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877-DNAH11:NM_003777:36
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127742=AAA_6=FE(19.9=100)
A:
NA
C2:
PF127742=AAA_6=PD(10.4=77.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)