HsaINT0049359 @ hg38
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21866470-21868007:+
Coord C1 exon
chr7:21866470-21866663
Coord A exon
chr7:21866664-21867858
Coord C2 exon
chr7:21867859-21868007
Length
1195 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
3' ss Seq
TATATTCTTGTTTTTTATAGAAA
3' ss Score
8.48
Exon sequences
Seq C1 exon
GCAATTGCCGTCATGGAAGAATTTCGAGGCATAGACCGAGATGTGGAAGGATCTGCCAAGCAGTGGAGGAAGTGGGTAGAATCCGAGTGTCCAGAAAAAGAAAAATTACCTCAAGAATGGAAGAAGAAAAGTTTAATACAGAAGCTGATTCTTCTGAGAGCAATGCGCCCTGACAGAATGACGTATGCTCTCAG
Seq A exon
GTGGGGTGGTCAGCATTTTTGGAAACATGTATTAGTTAACATAGAGGAAATGTAGTCTGAAGAGTTAGGAGGATCTGGTGGAAGTGTTTACCATCCATTTTGATGGGGAGTGATTCTGCTGAGATTTTGATATTATAATCACTGCTACTGTTAAAATTTGCTAAACACTAAACCATGTGCTAGGCAGACTCAGCACATTCTTCCCAAAAAAGCTTAATTCTGAAATCAGTACTGGAGACAGGGGACTGATGGAAATATTCCTGGAAGAGAAATGGGTGTCAGCAGAGTTCAGAGGCCAGGAACATGCATTCATGCATTATCCAAGTGTAATTTCCATCGTTTTCTTTCAGTGATGGCATTTTGGTTCTGAAGATTTTGCATGTCAAACAAAAATGCATTCCTTTCATGGAGTCACTCATAGTCCCTATAACTTTACAACCAATGCAGTTTCAAAGCAGAAACCCTTGTCTACATCTTGGTTTAAGTGTCCTTTTTCTTTGCCCTCTTGGCTTCTAAATGGTAATGTGCTGCTTAATTCACACAAGTCTCATTCTAATTTGAATTCACCAACCAAAGAGTTCTCAACTTCCTTCCCTATTGTGTTTCTTCAGTAATATTCATGTGCCTCAGGTTTTTTCCTTTGCTTTGTCTAGTTCAGCCAATTTTCCCTTTGCAGAAACCTCTGCTGAACTCTACTTTACAAGTTAATTCTGCTTAGTAGTACTTACTTTCTGCTAAATCTGATGCTGCTGGAAAATAATCCTTGCTTAATTGAGCCTCCCTGTGTTAGAAACACCCCAAAAAGCATTTGTATATTCATGAGAAGCCCAGCAGGCTGGAAAATTGCACTGTGGCAAATCTAATGAACTGTTAATAAGTAATGGGGGAATCTGGCAGGGGATTTGGGGGATACAAAGCCATAGCAGACAGCTGATGGCACTCAGGGGGGTCTCAGTAGCCCCCCAAAATGGAATGTAGGCTTCTGATTTTCAGAGCTTCTAAGGAAGAGAAGGATTTCATTGACACACCTACCGCATACATCTAGCTGGATTCATATTGTTATTCTAACAAGACATCCCATGTAATAAACCTGGTTACTTCTATCGTGTGCCTGTGTGGTTTAAGCTTATCCAAATGGTGACTCTTTTCAAGGTCAAAACCACTGATCATGTTTTTATATTCTTGTTTTTTATAG
Seq C2 exon
AAATTTTGTAGAGGAAAAACTGGGTGCGAAGTATGTGGAGAGGACCAGATTGGACTTAGTTAAAGCATTCGAAGAAAGCAGCCCAGCCACCCCCATATTCTTCATCCTGTCTCCGGGGGTAGATGCCCTTAAAGACCTGGAGATTCTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877:ENST00000409508:71
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(9.1=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(7.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAATTGCCGTCATGGAAGAA
R:
AAGAATCTCCAGGTCTTTAAGGGC
Band lengths:
342-1537
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development