HsaINT0049369 @ hg38
Intron Retention
Gene
ENSG00000105877 | DNAH11
Description
dynein axonemal heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:2942]
Coordinates
chr7:21899336-21900120:+
Coord C1 exon
chr7:21899336-21899448
Coord A exon
chr7:21899449-21899979
Coord C2 exon
chr7:21899980-21900120
Length
531 bp
Sequences
Splice sites
5' ss Seq
CTGGTAAGG
5' ss Score
9.68
3' ss Seq
TTTTTGTTATATTTCCAAAGCAA
3' ss Score
5.46
Exon sequences
Seq C1 exon
GTTCAATGACCTCCTCCTGCGATGCCGAGAACTCGATACTTGGACACAAGACCTTACCCTTCCGGCTGTCGTGTGGCTCTCCGGCTTCTTCAACCCTCAGTCCTTCTTAACTG
Seq A exon
GTAAGGGCTGACGCAGTGCAGCCCCTGATGCACACAGGACCACAGCCTAACCAGAAGCCCTGCTTTGTTTACCTATGATGGCGTCTCCTTGCCCTGCTCACCAATCCTCAAGCAGCAGCCATTATAGAAAGGACCAGCAGCTATAGAGGAAACAGAGTCCTGGGCAGGCGAGTAGCAGCAGGAGGGAAAGGACCTCCTATAGCAGCAAGAGTAGCCAAGTGAGGTGGGGCACGGTGTGCTCTTATTAAACATTTTCTGGAAAGGGCCACATAGCTTCTCTGCTACTGTAGTGCGAAAACCACAGACAATCCACAAATGGCTGTGACTATTCCAATAAAACTATCTACAGAAACAGCGAGCTTGTCCTGCAGGCCTTAGTTGGCCAACCCCCTGCTCCAGCGCAGCCATGTGCCAATGCCCAAGAACCTAAAACACCCTATGGGACTAAAGGATGCCTCAATTTACTGGTAGCTCCCGGGAACCTTACATGCAACACTTTTATCCTATTCAATTTTTGTTATATTTCCAAAG
Seq C2 exon
CAATCATGCAGACGATGGCTCGAAAAAATGAGTGGCCCCTGGATAAAACGCGCTTGACTGCTGATGTTACCAAAAAAACAAAGGAAGATTATGGACACCCGCCAAGGGAAGGTGCATACCTCCACGGACTCTTCATGGAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105877:ENST00000409508:80
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.125
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(5.4=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(6.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCAATGACCTCCTCCTGCG
R:
CCTCCATGAAGAGTCCGTGGA
Band lengths:
254-785
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development