HsaINT0049371 @ hg19
Intron Retention
Gene
ENSG00000174844 | DNAH12
Description
dynein, axonemal, heavy chain 12 [Source:HGNC Symbol;Acc:2943]
Coordinates
chr3:57528428-57530071:-
Coord C1 exon
chr3:57529924-57530071
Coord A exon
chr3:57528631-57529923
Coord C2 exon
chr3:57528428-57528630
Length
1293 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTT
5' ss Score
8.17
3' ss Seq
TATGGACTTTTTCTCCTCAGAGT
3' ss Score
9.12
Exon sequences
Seq C1 exon
GCCCTTCTCCAGCTACTCGTTTGAGAGCCGGTGGCGTTCCGGAGGTTTCTCCCTCGTTATCCCCCTGCCTTTCACCTGAGGAGAGGCTCTGACTGTCTCTCTCTCTCTCTGGCGTCTGCGCAGCGGGGAAGTAGTGAGAAACAATCAG
Seq A exon
GTACTTGTTCTCTGCTGTTCTCTTCCTTTCTCTCCCAGGGCAGGTATCGCGATTTGGGTGCCAACTTAAACACTCTTTCAAGGCAGGAATCTCCAAATCCTGTAGGCATTCATGGCAAATATAGTTGTTATCACAGTACAATTTTTTTTTGAGACGGAGTCTCGCTTTATCGCCCAGGCTGAAGTGCGGTAGCGGGATCTCAGCTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTTGTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGGCTCGAACTCCCGACCTGAGGTGATCCGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCTGGCCCACAGTAAAATTTTTGAGCATTTACATGACATTTTATATTTGCCATGCATCAAGTATGCCTATTTTTTGCTTGATCATAGCATCACTTTCTTGGAAGGCAGCAAGACTAAGATATCATACTGATGTTTAAAAATATTAATGATTGGCTGGGGGCGGTGGCTCACGCCTGTAATCTCAGGACTTTGGGGGACCGAGGCGGGAAATCATCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAACACAAAAAAGTAGCTGGGCGTGGTTGCGCACCTGTAGTCCTAGCTACTCGGGAGGCTGAAGCAGGAGAACCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCGCGCCATTGCACTCCAGCCTGGGCGACAGAGCAAGAATCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAACCATTAATGATGTTAAATATCAGCTTTTACTGGGAAGGGGATCATCCCTCAACAACTGGATTTGTTGTGGTGGTGGTGGTAGTGGTTTGCATCTCGGGAAAATTTTGCACCCAGAATGCTACAGCTGTAGGGATATTTACAGAGCATCTAATTCAATTCCTTAGTTTCATCCATTAGGAAACAAGCCCTGAAGGGGAACTGACTGGCTCATTGCTTCATAAGTGAGTTTTAGAGTTCTAACAGGAATCCCTGCCAACTTACCTCAACTGTCATTCTTTAGACTAATACCATACTTGGGAGGAAGATCCAAAAGTGTCTAGAATTTTACTTTTGGTATTGATATGTTAGATATGTTATGAATGTGTCGAGGCTTGCTGACATAATAATGGCTTTATGGACTTTTTCTCCTCAG
Seq C2 exon
AGTACAGAGTATTTTAATCTTTAGGGGATCAAGATGTCAGATGCAAACAAAGCTGCCATTGCAGCAGAAAAGGAAGCTCTGAACTTGAAGTTACCCCCCATTGTCCATCTCCCAGAAAACATAGGCGTTGATACACCAACACAAAGTAAGCTGCTAAAATACAGAAGATCCAAGGAGCAGCAGCAGAAAATTAATCAGTTAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000174844-DNAH12:NM_178504:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
5' UTR
No structure available
Features
Disorder rate (Iupred):
C1=NA A=NA C2=0.249
Domain overlap (PFAM):
C1:
NA
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCTTCTCCAGCTACTCGTT
R:
TTAATTTTCTGCTGCTGCTCCT
Band lengths:
342-1635
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)