HsaINT0049442 @ hg19
Intron Retention
Gene
ENSG00000185842 | DNAH14
Description
dynein, axonemal, heavy chain 14 [Source:HGNC Symbol;Acc:2945]
Coordinates
chr1:225237912-225239497:+
Coord C1 exon
chr1:225237912-225238078
Coord A exon
chr1:225238079-225239152
Coord C2 exon
chr1:225239153-225239497
Length
1074 bp
Sequences
Splice sites
5' ss Seq
ATAGTAAGT
5' ss Score
8.65
3' ss Seq
CTCAACATTCTTCTTTACAGATT
3' ss Score
8.72
Exon sequences
Seq C1 exon
CCACAATTACTCCTCTTTGCCAAGATCCCCAGCTGTCTATCTTCATTGATTTGGTTTCAATAATGGATTTACCTAATAAGACAGGAAGCATAATACATTATAAAGAGCAGACCAGATGGCCAGATTGTCACATCCTTTTTGAAACAGATCCTGCCTACCAAAATATA
Seq A exon
GTAAGTTTTAAAACAGTTCATTTTAGGAAATGTTTAAGGAGCAGAAACCCACTGAATTCTTAAATGAAATGAATTTATTGAAAAATTAGGGTATCCTATTCATAGCAATTGAAAAATCATTTCCAGCTTATCTCCCCATTTGTTTTTCCCATGATCTGTCATCGCTGCTCACCTCTGTGTGATTTTTCCAACTTCTGTGAAAATAAGTTTTCTCTTTTATGGCTACCTCATAACGTAGGCTCGTCAGTTGTTGACTTGCCATACCTCAACTCTTTCCATTAGCATCAACTGGGTATTTTTGTCCAAATTTACAAGAGAATCTAATTGGCTTAGATTGATTTAGGATTCTACCCTATCTAAATAGTTACGTCTTTGGTGAATTGGGTGAGGTCACATACTATATACCAGTGGCCCTTAACCCTTTTGGCACCAGGGACTGGTTTTGTGGAATACAGTTTGTCCATGGACAGCAGCTGAGGGGTGGTTTCTAGATGAAACTGTTCCACCTCAGTTCATCAGGCATTAGTTAGATTGTGATAAGGGATGCACAACCTAGATCCCTCACATGTGCAGTTCACAATAGGGTTCAAGCTCCTATGAGAATCTAATGCCACTTCTGATCTTGCAGGAGTGGAGCTGAGGCAGTAATGCTTGCTCACCCACCACTCACCGCCTGCTGTGTGGCATAGTTCCTAACAGGCCGTGGACTGGCACTGCTCTCTGGCCTGGGGGTTGAGGACTGGCCTTTTCTAGGGCTAAGCGTAGTATACTCTAAAACAGGGTAATAAGCAAGGGGATAAATGATTGGTGTTTCCAGTACATGGCTCAAAATAACATGTTAATTATAAAGTTAAATAGCCTAATAAGCCTTTAGGTAAAAGCCAAATATTAGAAAGCCATCTAAATTTCTTAAAGTCTTGTGTTTCCAACATATTTCGATTTTTAATAGAGGTTCTTAAAATAAACTCCACATAGCACTATTATTTTATTTTGTCAGAAACTATTAGCATGCCAAACCATTTTTCACTCTTAAAATAAAAATTCTGACTAACATCTCAACATTCTTCTTTACAG
Seq C2 exon
ATTGTGAATCTCCTGACTATTATTGGTAATTCAATGGGCCTAGTTAATGCTTACAGCCACAAGTTTATAAAGTATTGTACCATGACAGAAAAGGCCAAAATCATGAGTATGAAAATATCATCTATGGGAGAATTAACTTCAAAAGAATTTGAAGCTATTCTAAATAGATTCAGAAACTATTTTAGACATATTGTGAATATGGCCATTGAGAAGCGTATTGGTATTTTCAACGTTGTAAGTCTTGATTATCAATCAGAATGCTTACTGTATATTGACAACGTCATACATATGAGCCACACCCTCATACAATCTGTAATTGAAAAAAAGAACAAAAATTTATTGGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185842-DNAH14:NM_001373:16
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCAGATGGCCAGATTGTCAC
R:
GGGTGTGGCTCATATGTATGACG
Band lengths:
358-1432
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)