HsaINT0049720 @ hg19
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:2949]
Coordinates
chr16:20981114-20986737:-
Coord C1 exon
chr16:20986555-20986737
Coord A exon
chr16:20981313-20986554
Coord C2 exon
chr16:20981114-20981312
Length
5242 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGAA
5' ss Score
6.33
3' ss Seq
TGTCCTCATGCCGCCCACAGAAC
3' ss Score
9.88
Exon sequences
Seq C1 exon
GTAGCGGTTATGCAAAGAGAACTGACAGCTCTTCAACCTCAACTCATCCTCACCTCCGAGGAAACTGCCAAGATGATGGTGAAAATTGAAGCGGAGACGAGAGAAGCTGATGGAAAGAAACTTCTGGTGCAGGCAGATGAAAAAGAAGCCAATGTTGCTGCTGCCATTGCCCAAGGAATCAAG
Seq A exon
GTAGAAAGACTGAGAAGAAAGGGAGGGAACTGGTGCTGCCGAATGAGCGTGGTTATACCCATCTTACGGATGAGAAAAGTGAGGCTCAGAAAGGGTAGGCAAGGCTGGGCATGGTGGCTCACAGCTGTAATCCCAGCACTTTGGGAGACCAAGGGAGGTGGATCACCTGAGGTTAGGAGTTCAAGACCAGCCTGACCAACATAAAGAAACCTCATCTCTACTTTAAAAAAAAAAAAAAAAAAAAAAACTAGCCAGGTGTGGTGGCGTGCATCTGTAATCCGAGCTACTCAGGAAGCTGAGGCAGGGGAATTGCTTGAACCTGGGAGGCAGAGGTCGCAGTGAGCTGAGATTGCACCACTGCACTCCAGCCTGGGCGGCAAGAGTGAAACTCTAAAAAAATAATAATAATAATAAGGGGTAGGCGACTCTCCCAGCATCACATAGCTGATAAGTGATGAAGGAAGTTGTTCTGAAACATCGCTGAAACCAGGAAGCATTAAGACCCAACATATGGGCAGGTGTGGTGGCTCACACCTGTGATCCCAGATTTTTGGGAGACAAAGGCAGGAGGATCGCCAGAGCCTCGGAGTTTAAGACCAGCCTGGGAAACGTAGCAAGATTCTGTCTCTACAAAAAAAAAAAAAAAAAAAAAACACTATAAAACAGCCAGGTGTAGTGGCACACCCATGTAGTCCCAGCTACTCAGGAGGCTGATGTGGGAGGATTGCTTGAGCCCAGGAGTTTGAGGCTGTAGTGAACTAGGATCGTGCCACTGCAATCCATAGCTCACTGCAGCCTTGAACACTTGGACTCAAGTGATCCTCCCACCTCAGCCTCCCGAGTAGCTGACCAAGACCTTGTGTTGTCTAAAAAACAAAACAAAACAAAACAAAGTGGCCAGGGGCAGTGGCTCATGCCTGTAATCCCAGTACTTTGGGAGGCTGAGTGGGTGGATTGCTTGAGTCCTGGAGTTCAAGACCAGCCAAGTTCAAGACCAGCCTGGGCAACATGGCAAACCCCATCTCTACAAAAAATGTAAAAAAAAATTAGCCAGCTGTGGTGGCATGCACCTATGGTCCCGGCTACTCAGGAGACTGAGGTGGGAGGGTCCTGAGCCCAGGAGGTCGAGGCTACAGTGGGTCCAGGTCGCACCACTGCACTCCAGCCTGGGTGACAGAGCAAGACCCAGTCTCAAAAACAAACAAACAAAAAGACCCAATATGTTTTGACCTCATGTTTTACCACTTTTCCTTCATTCCCTGTACTCTGGCCATGTTGGTCTCCTAGCTATTTGTTAAATAATCATAAGCCGCACTCCCACCCCAGAGCCTAAGAACTGGCTGTTCCCTCTACACAGAATGCCCTTCCTTTTGATATCCACATGGCTGTTTCCTTCGTCTCCATTGTATTTTTGCTAAATTATGCCTGGCGTGTTGTAGGCGTGGAATAAATATTTGTTGGATGACAGAATGTGGAACCTAGAGGAAACCCGCTTGAAGGTGATTCTTGTGCCAGAGAGGAAATAGTCCTGGTAAGGGCTTGACCTACGTTCACGTAGTAGAAGAAAATCTACTTCTTCAATTAGCACTGATGTGATGTTGTATATTTCACAAAGCACTTTGAAGTACATGGTTACATTTGAGCATTACAACTACTTTGAGACTTCAGAATGACAGATAGGGCCGGGAAAGGTGGCTCATGCCTGTAATCCCAGCACTTCAGGAGGCCAAGGTGGGCAGATCACTTGAGGTCAGGTGTTTGAGAACAGCCTTGCCAACATGACAAAACCTTATCTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCACATGCTTGTAATCCCAGCTACTCAGGAGGCTGAGGTGGGAGAATTTCTTGAACCCGAGAGGTAGAGGTTACAGTGCGTTGAGATCGCACCAATGCACTCCAGCCTCAGTGACAGAGCAAGACCTTATCTCAAAAAGAAAAAAAAAAGAATGACAGACATGGGCATATGAGAGTTGACAGCATTGAGGTTCAGTGGTAAATTGACTTTCCAGAGCTGCATGGTTAGTGGGATTAGAAGCCAAGGTTCATGGCACTTACCTTAACATACTTGAACCTATGCCCCCACTTAACAGAAAATTCTCTCAACCATTCTTCAAACAAGGGCTTGATTAAAAAGCAGCCTATGTGTCTTCTATCATAAATAGGTCATGGCAGCTGGGCGAGGTGGCTCACGCCTGTAATCCCAACACTTTAGGAGGCTGAGGCAGGTGCATCACTTTAGGTCAGGAGTTGGAGACCAGCCTGGCCAATATGGTGAAACCCTGTCTCTACTAAAAGAATAAAAATTAGCCGGGCGTGGTGGTGGGCACCTGTAATCCCAGCTATTCAGGAGGCCCAAGCACATGAATCACTTGAACCTGGGAGGTAGAGGTTGCAGTGAGCTGACATCATGCCACTGCACTCCAGCCTGAGTGACCAAAAAAAAAAAAAAAAAAAAAAAATCACGGGGCATTGTCTCAGAAGGGCAGGCCTTTTTGATTGGCTTTTCTCCACTGAGTCCTGAGACCTGGCCTGTGGGAGATCCCCTGGGTGGGTCTGATCCCTGTCAGAGTCACATAATGAATACCCTGAATTACAGATGCTTTTTCACTTGTAGTCCTGGTAGAATAGACACGAGGTGAATGGAAACCATCAGTGATAATGGGCCAGCCATGATGGGTCATGCCTTTAATCCCAGTGCTTTGGGAGGCTGAGGCAGGAGGATGGCTTGAGGCAAGGAGGAATTTCAGACCAGCCCAGGTAACAATAGTGAAAACTCTTCTCTGCAAAAAACTAAAAAGAAAAAAATTGGTCAGGTGCAGTGGAGCACACCTGCGGTCTTAGCTACTCAGCAGCCTGAGACAGGAGGATCACTTCATTCCAGGAGCTGCAGTGAGCTATGATCCCACCACTGCACTCTAGCCTGGACAACGGAGTAAGATCTTATCTCAAAAAAAAAAAAAGAGAGAAAAAAAAATCAGGAGATTTCAAGTAACAATTCTGAATTTTCAGCTTTTCTTTGGAAAACATCGGGCAACCTGGCAACATCGGAGCTGCCCTCCCGGGTTGCACTCATCTTCGGTATTAAATAGATGCTGCCCCTGTGTGTTCCAATTCACCAAAGTCCCAGCCCCACCCACTCGCACTCACTGGCCTGGCCCCTGAGGCGCATGAATTGGCAACTCTTTAATGTTTCTGTGCTAGAATCAGGTACATCAGGGCTCAATTTTTGCTCTGTCCTTTCCTAGCTTCAGTTTCTTCATCTACAAAATGGGGGTACTAAGAGGAAAACATGTAACATTTGTAGCCTGTGCCAGAGCGTAAGGGTCTATGTTAGTGATTCTTCAAAACTGCTGTACTTTGCTCTATACCAAGGGGACTTGCCTATGTGACCAAGGCTAGCCCCTTTCCACATGTGGGTCGCAGAGGGAAGGAAAACAGCACAGCCAAGATTCTGCTCTGTAATGTCAGGCCAAACAGCGACTTGTTGGAGCAGGAGGGAGGTGAGTGATCGCACAAGGTTTGTAAGGCGGTGACCCAGGACGCCCCACTACACCCACTCCCAGGCAATAACTGCCACATCAGGTTTCGGTGCAAAGGGTGAGGCTCAAGTCTCTGCCATCCCATCCCTCTTCCAGGGAGTGACATCCTGGGATGAGTCAGGAAGTGGAAGAAACTACCCAGGGAGGAGGAGAAACCGGTGTCTGATTGTGCAGCTTTCCTGAGGCTTTTTTGTGGACCGGAATCCCTTCCTGGACCTTTCAGGGCTGTGGCCCTCCTGCCCAGGAGAAGTTGCTAATTTTCTCTAATCTCCTCACACTCCCAGAAATGACACAAGATGGAATAGTGCCCAGTAGGGTACCGAATGCACAGTAGGAATGCAAATGAAATCCATATTAGGAGTTTCTGTTTGATCCTAATTTGCCTTTAAGAAACATAAATTTTAGTGTTTCTTTATATGGAGACAAAGTTAGTTCCCTGCTCTTTACCAAAAAAGAAAAAAAAAAAGTGATTTGTTAGAAACTCAGAAGTACGGCTGAGCACAGAGGCTCATGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTATACTAAAAATACAAAAATTAGTCAGACCTGGTGGTAGGCACCTGTAGTCCCAGCTACTCGGGAGCCTGAAGTGCGAGAATCACTTGAACCCGGGAAGCAGAGGTTGCAGTGAGCCGAGATAGCACCGCTGCTACAGTCCAGCCTGGATGATAGAGCGAGACTCTGTCTCAAAAAAAAAAAAAAAAAAAGAATAGAGAAAAGAAAAGAAATCCATACTGGGAAGACAAAGACTGGAAGAGCAAGAATCAGGTCACCAACTCTTGATTCACAAGCGCAATGGTTTGCTTACATTGGTCAATTCTTTCCAATTATTTCTTTCCCCCCTAATGAGGATGATCAATGATACCAAAATTACTGTGATCTGATTACATTTCGTCACACTGCACTGAACTCCATACCTCTCAAACAATCCGATTGCTCTTTTCATGCTAAGACTCAGGGGCAATTTTAAATTATGTTTTTAGCATAGAAACAAATGTGGTAACAATGCCTATGTGAGATTTTTGTTTTGTTTTTGTTTTTAGACAGAGTTTCAATTTCACTCTTGTCGGCCAGGCTGGAGTGCAATGGCAAAATCTCAGCTCACTGCAACCTCCGCCTCCCCAGTTCAGGCAATTCTTCTACCTCAGCCTCCTGAGTAGCTGAGATTACAAGCGCCCACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTTGCCATGTTGGCCAGACTGGTCTGGAACTCCTGACCTCAAGTGATCCACCACGTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCTACTGTGCCTGGCCAAAAAAGCAAATAAGTTGAATGCTCAGATGTTCGGGACATCCAGACCACAGCCCCAAAAGGCCATGCATGTGTTCCGGCTGCTGGTTAACGGTCAGAGCCATTGTCCAGCTCCAGCGGCAGGCACCATGTTAAAGGGTATCTGGAAGAGGAAGCACCTCTTCCTTCTTCCTCATGTAGGAGTGGAGCTCTGCTTCGCCCCCATTGTGCCAGGCCCTGGGCACTCATCTCCTTTGTCCTCATGCCGCCCACAG
Seq C2 exon
AACGAATGTGAGGGGGACCTAGCTGAGGCAATGCCTGCACTCGAGGCTGCACTAGCTGCTCTGGACACCCTGAACCCGGCCGACATCTCGCTGGTGAAGTCGATGCAGAACCCACCAGGCCCTGTCAAACTGGTCATGGAGAGCATCTGCATCATGAAAGGGATGAAGCCAGAGAGGAAGCCAGACCCCAGTGGCTCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-DNAH3:NM_017539:51
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.098 A=NA C2=0.224
Domain overlap (PFAM):
C1:
PF127772=MT=FE(17.1=100)
A:
NA
C2:
PF127772=MT=FE(18.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)