HsaINT0049731 @ hg19
Intron Retention
Gene
ENSG00000158486 | DNAH3
Description
dynein, axonemal, heavy chain 3 [Source:HGNC Symbol;Acc:2949]
Coordinates
chr16:20944476-20946807:-
Coord C1 exon
chr16:20946670-20946807
Coord A exon
chr16:20944830-20946669
Coord C2 exon
chr16:20944476-20944829
Length
1840 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGG
5' ss Score
7.81
3' ss Seq
ATAGCTTTTTATTCTTCCAGGTA
3' ss Score
8.64
Exon sequences
Seq C1 exon
GAATGGATTGACAAGGGGCCCCCTGTGGTATTTTGGATCTCTGGATTCTACTTCACACAGTCTTTTTTGACTGGCGTCTCTCAAAATTATGCCCGGAAATATACCATCCCCATTGACCACATTGGATTTGAGTTTGAG
Seq A exon
GTAGGGGTGCTTTGGGTTAGGCTCACTCAAGGGGCTGACCAGAGAAAGCAATGTTGCCAATTTCCTTATGAGTCAAAAAATGTGGATGTGTTAAGACCCAAATGCTTCTGAAATGGTACATATGAAGCATTTAGCATAATTTACAGTAGCTCTAAAAGCTACTCCTAAAATAATTAGAGGATTCCCAATGCTTTGTCTCTGTGTATACAAAAAGGGAATCTTTCCAGATTCCGTCAGAACACCAAGAAAAATGAAGGCACTCTCCCACTCTGTTTGTTCAATGTGGTGGACTCTTCATTTACAAGAATGTTAATGCCCTTAGGTAGTCCTTTGCTTGGAGTAAAGTTAAAAGCATGGCCAACAGTCAAGCATCAGCCTGTCATATATAGAGAGTAGAATGGCTACGATTGACTGTTACAGAGCATTGTAGAATTTTAAATTATACGGAAAGATCCTTTGAAATCATCTAGTCCAGAGGTCACAAACTGGTTGCCCTATGTCTTAAATCAGTTTATGAATGAACTTAACTTGATTAGCCTTTGAAGACAATGTTAAGCCAAAATAAATACAACAAGAAAAAAAATGACTAGGATAAACATTGAAAAAAAGATAAAACCATCTTTCTTGATGTTGAAATGATTGTATACCTAGAAATCCGAAGTGATTAAAAACATAGAGTCCTTTACTTGCAATGGTTCAACTTACAATTTTTTGACTTCATGATGTGAAATCAGTACACATTCAGGAGAAACCACACCTTGAGTACCCATACACCCATTCCATTTTTCACTTTTAGTATAGTATTTGATAAATTACATAAGATACTCAACACTTTACTATAAAACAGACTTTGTGTTAGATGATTCCTGCCCACTATAGGCTAATGTAAGTGTTCTAAGCACATTTAAGGGAGGCTAGGCTAAGCTATGATATTTGTTGTAGGTTAGGTATATTAAATGCAGTTTTGGCTTACAATATGTTCAACTTATGATGGGTTTATCAGGACATAACCCCATTGTAAGTTGAGGAGCATCTGTAGAAGAATTCACAAGGTCACTGGATATTGGTTAAATTTATAAAAATCAATAGCCTTTTCCTATTCTTCCAATATATACTTAGAATTAGAAATGGGAAAAAATTCCATTCACCATAAAAATTTTTTAAAGTATAATTTGAATGATTTTAAATGGAGTTTGTGCTCTCTGGTTCACCATAATCCCCACCCCTCCCTATTCTCCTATGCTTTGTCCATTTTCTGCAATTACCTAAAGGAATTTGAGTTTACCACCTCTGAATCTAAGCAGTGGTGTGCTGGAGCTCACTCATATCAGCTCACCAGGGCCAACTGTTACATTTTCAGGAATTTTGTGAGCTGGTTGTTAAATAGTTGGTAGGCTGAAATTGACCATGGTGGAAGTCTTTATACCACAAAAACTAGAAATCAAGGCTTTATTCTCCCCACACTCATCTCCAGAACTGTTTATCCAGTCTGTCTCTGTATCTGAATCTAACCCCTCACTTTATAAATCCAGATCCAGAAAGGGAAGGGATTGTGCAATCACTAAGCTAGTTAGAGGTAATGTGTTAGAATAATGTGACTCCTACTTGAGTGCATTCTCTAGCCCACCATTGGGAAGGGCAGCATACTGACCAGGAGTCAGGCCTGGCCCATGTATGGTGGGCAGGAATATTATCACAGAAGCCCCATTGTCCCTGGATCCTGGGAGAGGTAGATATTGCAACCAGGTTGCACTTTGAGTATCAGAAGATTCCAGGCTCTTAAAGCTGCCCATGTAGGAAAATGGCAGGCAATGGAGCTCATAGCTTTTTATTCTTCCAG
Seq C2 exon
GTAACCCCACAAGAAACAGTGATGGAGAATAACCCCGAAGATGGGGCCTACATCAAAGGGCTCTTCTTAGAAGGTGCCCGTTGGGACAGGAAAACGATGCAGATTGGGGAATCTCTCCCCAAAATCCTCTATGACCCACTGCCCATCATTTGGCTGAAACCTGGGGAGAGCGCAATGTTTCTGCATCAGGACATCTATGTGTGTCCAGTCTACAAAACAAGTGCCCGCAGAGGAACCCTCTCCACCACAGGCCACTCTACCAACTATGTCCTCTCCATTGAGCTTCCAACAGACATGCCCCAGAAGCACTGGATAAACCGAGGGGTGGCCTCACTGTGCCAGCTGGATAACTGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-DNAH3:NM_017539:61
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.009
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(6.3=100)
A:
NA
C2:
PF0302810=Dynein_heavy=PD(15.9=95.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCCGGAAATATACCATCCCC
R:
GGCATGTCTGTTGGAAGCTCA
Band lengths:
347-2187
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)