HsaINT0049794 @ hg19
Intron Retention
Gene
ENSG00000039139 | DNAH5
Description
dynein, axonemal, heavy chain 5 [Source:HGNC Symbol;Acc:2950]
Coordinates
chr5:13752243-13753658:-
Coord C1 exon
chr5:13753342-13753658
Coord A exon
chr5:13752399-13753341
Coord C2 exon
chr5:13752243-13752398
Length
943 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATT
5' ss Score
8.55
3' ss Seq
CCTTGTGATCCTGTTCCTAGATC
3' ss Score
9.23
Exon sequences
Seq C1 exon
GGGATGTACTGTTGGCTACAGCTTTTCTATCTTATTCTGGTCCATTTAACCAAGAGTTTCGTGATCTTCTGTTAAATGACTGGCGGAAGGAAATGAAAGCCCGGAAAATTCCATTTGGAAAGAACCTAAATCTCAGTGAGATGTTGATTGATGCTCCTACTATTAGTGAATGGAACCTCCAAGGTCTGCCAAATGATGACTTGTCCATTCAAAATGGAATTATTGTCACGAAGGCATCTCGTTACCCTTTGTTAATTGATCCACAGACTCAAGGCAAGATCTGGATTAAAAATAAAGAAAGCCGAAATGAACTCCAG
Seq A exon
GTAATTTGTGTTTTAGTATGTTTATGCTACCGGTTAAGTTTTATTGCCTCAGATAAACAAAAATCCAAGAGTAAAGAAATATTTGAAAACACTAGAGATGTTTTTGTAATCCTAGGTAGAGCAGTAGCAGATGCAAGCTTAAATCTAATATAAAAATATTTTCTAAAACTTTCATTATTTGCATTTGTGTTGATCTCTACCAATGCCATCTTTCAATGGTTTCAGGCTATTCTGTCAGGGTCCAGGGCTCTCTTTGATAAGTACAGAACGGCAGAGCTGTATCACACAAAGTGTGCAGCACTTTGCATGAATACTTCCTAATTATTACATTATTATTTGTCACAAAAGTGGTAGTGGTGAAGAAAAAACATTGTTCCCACACAGAGCCTTTACATGCTTCCCAATAAAACAAAATGATAGTTTGTTAAACAACAATGGAAACAGTTACACTTCTTTACAATTTCACCAAGTGTGGGTTTCAAAGCCAAGGATCTCTAAAAATCTATATGAAAGTTGAATGCCCCTTATCCTAAATACTTGGGATCCGAAGTGTTTCAGATTTTAGATTTTGGAATATTTGCATGTACATAATGAGATAACTTGAGGATGGGACCCAAGTCAGAACACGAAATTCATTTATGTTTCATATACACCTTCTTCATATATTTGAAGGTAATTTTATACAATATTTTAAACAATTTTATGCATGAAACAAAGTTTGTGTACATTCAACCATCAGAAAGCATAGGGGTCAGGTGTGGAATTTTCCACTGTGGGCATCATGTGGGCTCTCAACAAGTTTTGTATTTGGGAACATTTTGGATGCTCAATTTGTATTTGTCTCTTGCAGTAGAATGCTTTAGGCTTCATTTGAAAACAGTTATCCCTGTGCATTGCTTCATGGTAATGTCTGCCAATAGCAACCTTGTGATCCTGTTCCTAG
Seq C2 exon
ATCACGTCTTTAAATCACAAGTACTTCAGAAACCACCTGGAAGACAGCCTTTCTCTTGGAAGGCCTTTGCTTATTGAAGATGTTGGAGAGGAACTAGATCCAGCACTAGATAATGTTTTGGAAAGAAACTTCATTAAAACTGGGTCTACCTTTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000039139-DNAH5:NM_001369:63
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127772=MT=PD(8.6=28.3),PF127812=AAA_9=PU(25.1=54.7)
A:
NA
C2:
PF127812=AAA_9=FE(22.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCGGAAGGAAATGAAAGCC
R:
TGCTGGATCTAGTTCCTCTCCA
Band lengths:
342-1285
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)