HsaINT0049978 @ hg38
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr6:38842368-38842903:+
Coord C1 exon
chr6:38842368-38842505
Coord A exon
chr6:38842506-38842662
Coord C2 exon
chr6:38842663-38842903
Length
157 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
TTTCTCTTTCTTTCTGAAAGATG
3' ss Score
7.77
Exon sequences
Seq C1 exon
AAAAGAACTCAACTTGCTGCAGAAGCTGTATGGATTGTATGACACCGTAATGAGCAGTATTAGTGGTTATTATGAAATACTTTGGGGAGATGTAGATATTGAAAAAATTAATGCAGAACTGCTGGAATTTCAAAACAG
Seq A exon
GTGAGTTTCAATGGAATTTTTTATAATGCCTGTCTTCTTAGGATCCTATAGGTATTTCAGAAGCTAATTTATTCCCTAATATAATAGTGTATATACATAAAACCTTCCTCAAATAAATGTGAAGGTGGCATATTTTTTTTCTCTTTCTTTCTGAAAG
Seq C2 exon
ATGTCGTAAACTTCCAAAAGGACTTAAAGATTGGCAAGCTTTTTTGGATCTCAAAAAGAGAATTGATGATTTCAGTGAGTCATGTCCTCTACTGGAAATGATGACCAATAAGGCCATGAAACAGAGACACTGGGATAGAATCTCCGAGTTAACTGGAACCCCATTTGATGTGGAATCTGATTCTTTTTGCCTTAGAAATATCATGGAAGCACCACTCCTTAAACATAAGGATGATATTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721:ENST00000359357:32
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF083938=DHC_N2=FE(11.1=100)
A:
NA
C2:
PF083938=DHC_N2=FE(19.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGTATGGATTGTATGACACCGT
R:
CAGTGTCTCTGTTTCATGGCCT
Band lengths:
246-403
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development