HsaINT0049992 @ hg19
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein, axonemal, heavy chain 8 [Source:HGNC Symbol;Acc:2952]
Coordinates
chr6:38834545-38835972:+
Coord C1 exon
chr6:38834545-38834652
Coord A exon
chr6:38834653-38835837
Coord C2 exon
chr6:38835838-38835972
Length
1185 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACT
5' ss Score
8.63
3' ss Seq
GCCCTCTTCTCCCATCTCAGGTT
3' ss Score
9.9
Exon sequences
Seq C1 exon
ATCATTATGAGAGTTAAACTTGCAAGCTGTGGTTTTCTTGAAAATGTTATCTTGGCTCAAAAATTTTACGTTCTTTACAAACTCTGTGAAGAGCAACTTACTAAACAG
Seq A exon
GTAACTTTATAGATCTGCTTTCCTCCTAGCAATAGTATTTGGTTTTTTTGCTTTGTAATTTTCCCTTGATAAATACTCATCAGTGAGTTAAAATCTCATTGACTCTTTTCTAAAATGCTTTTAGAATTAATTTTACCTATTGGTTGTGTATTTTTAAGACCCTTTTATTTTGAAATAATTGTAGATTCACAGGAAGTTGCAAAGGAATGTACAGGGAGGCATGTACCCTTCACCCTGCCTTGCCTGGTGGTTGACATCTTGTAACTGTAGCGCAATAACAAAACTGGAAATGGACACTGAAGCAGTCCACAGAGTTTAAGGTTTCATCAGTTATACATGCACTGGTGTGTGTATATGTGTGTGTGTGTGTGTGTGTGTGTGTAGTTGTATGGAATATGTAAGATACGGCTCTGTTCCATCACCACAAGGTTCCCTCATGCTACTTTATAGCCACACCCACCTCTCTCCCAAATCCCTAACCCATTAACCTTTTCTCCATGTCTAGAATTTTATTGCAAGAATGTTATGTAAACGGAATCACATAGTATGTAACCTCTTGGTTATGCATTTAAAAATCTATTGTTTGGGCCGGGTGCCGTGGCTCACGTCTGTAATCCCAGCATTCTGGGAGGCCGAGGCGAGTGGATCATGAGGTCGGGAGATCGAGACCATCCTGGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAAAAAAAAAAATTAGCCAGGCGTGGTGGCACGCGCCTATAATCCCAGCTACTGGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGTGGTGGTTGCAGTGAGCCGAGGTCCCGCCACTGCACTTCAGCCTGGATGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAACAAAAAAGAAACTATTGTTTGTTGCTCAGACTGTATCAGACTATATTATTCTCAAAAGATATTTAAGGTGTGAATACTTACTTGATCTTGCAGCTTGGATTTTCCCATGGAATGATCATATTTCAGTCAAAGGAAAGGCAGGAAGTTGAGCTAATAAACCTTTGTGGCTTAGTCACCCCAAAACTATCCCATATAAGTATCAGAATCGACCTATATGCATAGAGTGAGCCGTGAGTCTATGTTTAGTTTTTCAATTAAACCATCTTTTTGCCCTCTTCTCCCATCTCAG
Seq C2 exon
GTTCATTATGACTTTGGATTGAGAAATATTCTGTCTGTATTGAGGACTCTTGGATCTCAAAAAAGAGCCAGACCAGAAGATAGTGAATTAAGCATTGTCATGAGAGGACTAAGAGATATGAACCTTTCCAAACTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721-DNAH8:NM_001371:45
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127742=AAA_6=FE(15.1=100)
A:
NA
C2:
PF127742=AAA_6=PD(10.3=53.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TATGAGAGTTAAACTTGCAAGCTGTG
R:
CAGTTTGGAAAGGTTCATATCTCTT
Band lengths:
238-1423
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)