HsaINT0050007 @ hg38
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr6:38898258-38899906:+
Coord C1 exon
chr6:38898258-38898380
Coord A exon
chr6:38898381-38899775
Coord C2 exon
chr6:38899776-38899906
Length
1395 bp
Sequences
Splice sites
5' ss Seq
AAGGTCCTA
5' ss Score
-0.7
3' ss Seq
CGTTTTAAATCTCAAAACAGATT
3' ss Score
6.14
Exon sequences
Seq C1 exon
ATGCCATCCTTTGACTTTCTGGCTGAAAAACTCCAGTTTTACCAGAGACAGTTCAATGAAATCATTAGAGGAACATCTCTTGATCTGGTGTTTTTTAAAGATGCAATGACTCATCTTATTAAG
Seq A exon
GTCCTAACTATTGCCTATTTACTGATATAAATAGATGATTTAAAAGCTTCGTATATTTCATAGATAAATTTTTTGAGAGAATAACTATATACTATCAGGTACCGTATAGAAGACTGTACATAGGTTGGGTCAATTCACTGTCCCAGAAAATAAAGGCTTAATAGGAAACCCTTTATTTGAATCCATCTACATGGCAGCAAATGTCTTTCAAGGGCAAATAGATGGTTTTCTGTTCAGAGCTTTTGGCACACTGAGTCAACAAGAAAGTATGGAGAACCTTTAGAAAGTATGGAGAACCCTGTGAAAAAATATACTTCCCTCAAATTATATTTTGATATTATGGGAATTCTGTTGCCCATGGAGGAAAAGATGTTGCTTTTAAAAGTGTCAATGTTATGATTGACTTACAGGTGATGGGACAGGGGTAAGGTTGATATATAGGACTGGTGAGAGAATAGAAGCCAGTTAGAGGTAACACGAAAAAGGGGTGTTTTCACACTAATCTATTCAACAAGTAATTATTGACCATTCACCGTGGCTAGATCTTGAGGTTCTGAGATCCTATTCTGAGTGCAAAGCCATAAGTGATTAATATATTTTAAAATATACTGATAGAATTTACACATACCAGGGTGTCATTATTGATCCACCATCTGCAAAACTTGTATTTTTTTAAAAATTATTTTTAGTGGTGATAGTGAATTTACTGATCCATCTAGACTTTCTCCCTAATTGGTGACAATAATATAAAAGACAGCTTTTTAGCAATGTCTTCAATTGGCCTGCATGAGATTTGACCCACAATTTGAGTCTTATCTTCACTGAGGAAATCAACCATAGAAAAGCAACACAACATGAAAGGCTGTCTCTCCAAGTTGGCTTCTAGAAACATCCTCCTACCCCACTGTAAATAGAATTATGGTACTTAAAAAAATTTGTTGGCAGAGATATGATAGAGTTAGTGTTCATTGTTGAGTTAGGTGTCTACATGATTCAGTGTGTCAGGCTGATGAATAATAAAAAAACAATTGTAAACATTTCTTATATCTTCTGCAGATTGGGAAGAGCAGCTCCACTATCCATTGGGTCTAAAAATAATAAAATTCTACATGCGTGCACACGCATGAACACACACACAGAATAGTTTTAAAATAGAAGGGAGTAAATCCAGTTTGTTCTGTTCTTCATGATGTAAACATAGATGGTCAAGGAAAGATTCGAGCTGAACAAATCAGTATTAAACTTTAATTTTAAAAATTCTGTCATAGACCATTAACGAGGAAAAAGTCTAATATCATCTAGAAACATATGATCAAAACTTGGGCTCATTTAGTGCAAGAAAATGTAAACATTGCATTCTTTTTTCAAATAAGCACGTTTTAAATCTCAAAACAG
Seq C2 exon
ATTTCACGAATAATTCGAACGTCGTGTGGAAATGCATTGCTGGTGGGTGTTGGTGGTTCCGGAAAACAAAGTCTTTCAAGATTGGCCTCTTTTATTGCTGGCTATCAAATATTCCAGATAACATTAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721:ENST00000359357:59
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127802=AAA_8=PU(8.4=56.1)
A:
NA
C2:
PF127802=AAA_8=FE(15.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGCCATCCTTTGACTTTCTGGC
R:
TGTTATCTGGAATATTTGATAGCCAG
Band lengths:
246-1641
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development