HsaINT0050026 @ hg38
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein axonemal heavy chain 8 [Source:HGNC Symbol;Acc:HGNC:2952]
Coordinates
chr6:38937974-38938988:+
Coord C1 exon
chr6:38937974-38938226
Coord A exon
chr6:38938227-38938797
Coord C2 exon
chr6:38938798-38938988
Length
571 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
ATTCTTAAAATGTGTTTCAGATC
3' ss Score
8.05
Exon sequences
Seq C1 exon
GCTCATTGGTAGATGACGAATCTCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGAAAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAACGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTACTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTATCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAG
Seq A exon
GTGAGTCCTCACTACCTTCATCCAAAAGTGGTGACTTAAAAGTTTGCTTGTATTTCTACTCTTTTAGAAATTGCTTTTTCACTATTCACAATAGCAAAGACATGGAATCAACCTAAATGCCCATCAACAGTAGAGTGGATAAAGAAAAGGTGGTACATATACAACGGGGAATACTATGCAGCCATAAAAAAGAATGAACTCATGTCCTTTGCAGAAACATGGATGAAGCTGGAGGCCATTATCCTTAGCAAACTAACACAGGAACGGAAAACCAAATACCGCATAGTCTCATTTATAAGTAGGAACTAAATGATGATACCACATGGACACATAGAGGAGAACAACAGACACTGTGACCTGTCAGAGAGTGGAGGGTGGGAGGAGGGAGAGGATCAAGAAAAATAACTAATGGGTACTAGGCTTAATACCTGGGTGATGAATTAATCTGTGCAACAAACCACCATGACATAGGTTTACCGACGTACAAACCTTCATGTGTACCCCTGAACTTGAAAGTTTTTTAAAAAAAGAAATTGCCCTTTGCTTCTTTGATTCTTAAAATGTGTTTCAG
Seq C2 exon
ATCTGAAAAGTCACCACTACCTCAAAAGAGAATTACAAATATTATCGAGTACCTGACATATGAAGTTTTTACATACTCTGTCAGAGGCCTATACGAAAACCACAAATTCCTGTTTGTACTCCTCATGACCTTAAAGATTGACCTTCAGAGAGGGACAGTTAAGCACAGAGAGTTTCAAGCTCTCATTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721:ENST00000359357:76
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127812=AAA_9=PD(10.0=27.1)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAAAGTTGCATGTGGCTGC
R:
ACTGTCCCTCTCTGAAGGTCA
Band lengths:
342-913
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development