HsaINT0050645 @ hg38
Intron Retention
Gene
ENSG00000106976 | DNM1
Description
dynamin 1 [Source:HGNC Symbol;Acc:HGNC:2972]
Coordinates
chr9:128222793-128224389:+
Coord C1 exon
chr9:128222793-128222860
Coord A exon
chr9:128222861-128224250
Coord C2 exon
chr9:128224251-128224389
Length
1390 bp
Sequences
Splice sites
5' ss Seq
TAGGCACGT
5' ss Score
0.42
3' ss Seq
CTCCCGCTCCGGGCGTTCAGAAC
3' ss Score
5.26
Exon sequences
Seq C1 exon
ATGGAGTTTGATGAGAAGGAACTCCGAAGGGAGATCAGCTATGCTATCAAGAATATCCATGGCATTAG
Seq A exon
GCACGTATTGGGGCCTGGGAGGGTGGCTGAACCCCAGAAGTAGGGGGTCTGGGACAGAGGCACAGGGAGTGATGAAGTGGGCCTCCCTCAGGAAGGACTGAAAGCTCTGTTCCCCAGTCCTCTCGACCCCAACTTTCTGGCTCCCTGCATGACAGGCTCCAGCTTGGGGAGGTGGACCCGGGCCACCCCGCCTACTGCAACTTGCTGGGCCAACTGGGCACAGCCCAGGGCGCAGGTGGCCGGGGAAACACCCTCTGGGGCTGGGCCCATCCCCAGGGTGAGATAGCTCCCCCAGTGCCACCCAGGTAACCGGACAAAGATGTCCAAACCACTACGAGGGCCTGGGGTGGAGCATCTAAGTATGAGGCTGTGTCCTTTTATGACGGCCGGGGACTTTGCAATCCTCCACACCCTCCTGTATTCACAGTAGCCCAGAGTCAGTCCCATTCCACCCCACCGCCCTCCTTCTAGGCAACCCGTGGAGTAGGAAACAGGATTGGGAGGTGGAATCTGTTCCTTAAAAGCTTAGATCCCCTTCAGGGACCCAGATCTATGCTGTGTTCATCCAACAAATCCACTGGGCCGGAAAATTTAAAGCACCTACCCTATGCCAAGCAGTGAACAAGACCCAGTGTCCCCTTGCTCTCATGCAGGTTCATTTCCAAGATTTGGCATGGAATTTACTTCCTGATAACTGCACTGGCCAATTCACAGAAAAAAGATCTCTTTCCTAGTCTTAAAACAAAACACTCTATTCCTGGAAAGGCTCTTATGGAGAACCACGTTTGGCAATTTTCAAGCCATTTCTGGCCATAGAACTTCCTATATGCACAGACCCTTACGAGGAAGCAGGACTTACATATCAGATACTCAACCACCTTGTCTTGCCCCAAAGAGCCTCATTAGGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGAAGGCCGAGGCAGGCGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAAAATACGAAAAAATTAGCCGGGCGTGGTGGCAGGCGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAATAACAACAACAACAAAAAACCCTTCATTAGAACCCCTCCCTCCCATTTTACAACTGGGGACACTGAGGCCCAGAGAGGGGTAGTGGAAGGGCCCCTCAGGCAGAGTTCGTGGGCTTGGGGAGGAGCCTCGGCCTGGCCCTCCTGGCCGGCACTGGCCTGTGACACTCTGCCCTTCTCCCGCTCCGGGCGTTCAG
Seq C2 exon
AACGGGGCTGTTTACCCCAGACATGGCCTTTGAGACCATTGTGAAAAAGCAGGTGAAGAAGATCCGAGAACCGTGTCTCAAGTGTGTGGACATGGTTATCTCGGAGCTAATCAGCACCGTTAGACAGTGCACCAAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106976:ENST00000372923:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(21.3=100)
A:
NA
C2:
PF0103115=Dynamin_M=FE(15.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGGAGTTTGATGAGAAGGAACTC
R:
TTCTTGGTGCACTGTCTAACGG
Band lengths:
206-1596
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development