HsaINT0051453 @ hg38
Intron Retention
Gene
ENSG00000115325 | DOK1
Description
docking protein 1 [Source:HGNC Symbol;Acc:HGNC:2990]
Coordinates
chr2:74555575-74556078:+
Coord C1 exon
chr2:74555575-74555668
Coord A exon
chr2:74555669-74555893
Coord C2 exon
chr2:74555894-74556078
Length
225 bp
Sequences
Splice sites
5' ss Seq
AAGGTAGAC
5' ss Score
7.07
3' ss Seq
TAATCGTGTATGCCTTCCAGGAT
3' ss Score
6.83
Exon sequences
Seq C1 exon
AAAGGCAGCTGGACTCTGGCGCCTACCGATAACCCACCTAAGCTTTCTGCCCTGGAGATGCTGGAGAACTCCTTGTACAGCCCTACCTGGGAAG
Seq A exon
GTAGACGCCTCAGAAGCCCGGGCAGGGATGGAGTGAAGAGGAGGAGGGCCGAGGGCCTTTGGGAAGTGGGTGGATACCCAGGGGCCCATGGGGAAGTAAGAAGTAGGAAGGCCCTGAGATCTGGCTTCCGAGTGAGTGCTTGGACACTATGCTCATGAGTCCTCTGGGTCCCCACTGCTGCCCCCGTCCCTCCCCCGCAGCTGTCTAATCGTGTATGCCTTCCAG
Seq C2 exon
GATCCCAATTCTGGGTAACGGTGCAGAGGACTGAGGCCGCCGAGCGCTGTGGCCTGCATGGCTCCTACGTGCTGAGGGTGGAGGCTGAAAGGCTGACTCTCCTGACCGTGGGGGCCCAGAGTCAGATACTGGAGCCACTCCTGTCCTGGCCCTACACTCTGTTGCGTCGCTATGGCCGGGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115325:ENST00000233668:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.091 A=NA C2=0.015
Domain overlap (PFAM):
C1:
PF0217412=IRS=PU(1.0=3.1)
A:
NA
C2:
PF0217412=IRS=FE(58.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAGGCAGCTGGACTCTGG
R:
TTGTCCCGGCCATAGCGA
Band lengths:
278-503
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development