HsaINT0051469 @ hg38
Intron Retention
Gene
ENSG00000125170 | DOK4
Description
docking protein 4 [Source:HGNC Symbol;Acc:HGNC:19868]
Coordinates
chr16:57475506-57475957:-
Coord C1 exon
chr16:57475850-57475957
Coord A exon
chr16:57475621-57475849
Coord C2 exon
chr16:57475506-57475620
Length
229 bp
Sequences
Splice sites
5' ss Seq
AAGGTTAGG
5' ss Score
6.06
3' ss Seq
CCTTGTGGATGCTGTCCCAGGTG
3' ss Score
5.85
Exon sequences
Seq C1 exon
ATCTACCGGAGGTGCTGGCTGGTGTTCCGGAAATCCTCCAGCAAGGGGCCCCAGCGGCTGGAGAAGTATCCAGATGAGAAGTCGGTGTGCCTCCGGGGCTGCCCCAAG
Seq A exon
GTTAGGAGGCCTGGGCCCTAGCTCCCCCAAGTGGCAGGGCTGTGGGGGATGGAGAGAGAGAGAGGGAGAGAGGGGAGAGAGGGAGAGAGGGGAGAAAGGGGGAGAGAGGGAGAGGAGGAGAGAGAAGGAGGAGGGGGGAGAGAGGGAGGGAGGGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGATGCACTGGCCTGGCTAAGTCCCTTGTGGATGCTGTCCCAG
Seq C2 exon
GTGACTGAGATCAGCAACGTCAAGTGTGTTACGCGGCTCCCCAAGGAGACCAAGCGGCAGGCGGTGGCCATCATATTCACTGATGACTCGGCACGTACCTTCACCTGCGACTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125170:ENST00000340099:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.001
Domain overlap (PFAM):
C1:
PF0016924=PH=FE(33.7=100),PF065348=RGM_C=PU(36.6=83.3)
A:
NA
C2:
PF0016924=PH=FE(36.5=100),PF065348=RGM_C=FE(46.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGGTGCTGGCTGGTGTTC
R:
CTGAGTCGCAGGTGAAGGTAC
Band lengths:
215-444
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development