HsaINT0052324 @ hg19
Intron Retention
Gene
ENSG00000171587 | DSCAM
Description
Down syndrome cell adhesion molecule [Source:HGNC Symbol;Acc:3039]
Coordinates
chr21:41496122-41505936:-
Coord C1 exon
chr21:41505781-41505936
Coord A exon
chr21:41496256-41505780
Coord C2 exon
chr21:41496122-41496255
Length
9525 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGA
5' ss Score
7.23
3' ss Seq
TAAACACACGGCTCTTCCAGTTC
3' ss Score
3.88
Exon sequences
Seq C1 exon
AGCTGGGTGAGATTAAAAACATCACCACCACACAGCCTTCACTGGAGCTGGACGGGCTGGAAAAGTACACCAACTACAGCATCCAGGTGCTGGCCTTCACCCGCGCAGGAGACGGGGTCAGGAGTGAGCAGATCTTCACCCGGACCAAAGAGGATG
Seq A exon
GTGAGAGACGGGTGGGCGGTGGGTCCCAGCAGTTGCTGGAAGGGCTGGGTCACAGAGAGCTCACTTGCCTTTACCCTGCAGTTCATCAGGCTATTCTCAGTGCAAACCTTTGCTGCCCTCCCAAAATATCCCAGTGCAATTCAGACCATTAACTTCCTCTCTTGCCTTTGCTTGATGTGTCTAATCCATTGCTTCTTCTTCCTCTATATTTTTTCTTCTTTCTTTTCTTTTTTTTTGTTTTTTGTTTTTTTTGGCCAAGTATTATTGTAAATAGAAACTCATTTTATCCTAGAGCTGTAATACTTGTCATACATGTTTTGTATCTTGTTAGAATAATTTTAGTAGCTATTCAGCTATTAGTGTAAACTCTGATTAAATCCATCCTTCCACTTCTTGAAAATTATGTACAGACTGAAGTTCTATTATTCTTTGCCAGCTGAATCACTTTAGAATAAGTCCTTAATTTGAGAACTTCATGTTAATTTTTTTTAATTCTTGCAAGAATTCATGGTGATTTAGTAAAAATTTAAATTGCTGCTCATTTTGTTCTACAACAATAATTCTTGCTGTTCCTTACAATTTGGATTGGGTTGTGACTATTACCCAAACGTACAAAAACCATACAACAAAGGTTCTGTATTATTTTAAGGGAAACTCTGAGGGGCCTTGGCCAAGCCTGTTTAAGGAACAGATAAGTTCTGATAAATACTACCGTGGTAGTGAGAAAAGTAGCCTCCACCTTAATAAAGGAAGGAGCAACTGATGTCAAATTGATGCCCACATAGAACCTTCCCAAAATATTCCAGCACAGAAGTATACATTGAGATGAGACATTAGCAGATCTAAATGCTGTGCTGGATTGTCTCTGCAACTTTTGTCTTCTTGCCGGGACTCTGTTCCCCAAGCAGTACAGGGGCGGGAAAGCTGTTGGCCATTGCTGGTCACCTCCTGTGTATGGGCAGGTTTGATGTCTATGCTATCTCCCCCACTACTAGAGTATCAAAAATGCTGTTATTCCATCCCATATCTGCTCTGATGGAAGCAAAGAACACCTGCTCAGGGGCCATGATACGCTCTTCTCTTCAGCCTTTCTGCCCCTGACAATGACTCCCTGTTATTCTGAGCCTGCCATCTTCCACGTCACTCTCTGCTCTCACCTTGGCAAGCCAGGCCTTGCTCCTCCGAGCAGCCCCAGGCATCCACTCTCACCTGGTGTTTTTGCTGCCTCTGTAGCCCTTCTCACATTGTAATGTCTACACCCAAACTAATCCTCATTTGCTTTAGTTTTTTTCTAAAATGCACAGGTAGTCCTTCCAGGGAATGTGCAGGTGTCAGCCAGTTCTGCTCTAAGAAATTGGATTATTTAGGGAATCTAAGGTTCAAATGTAATGCCATTAGGAAGTCACACATCAATAGAGATATCTAGAAAGCTAAGTCCTGAGTGAAGGCAGCCATAAGTTAATTTTTTAAAAATGTAACAGACAAACAGCTGTGCAAATGCTGGCTCTGTCACCTGCTGCCCGTGGGTCTTTGGGCACCTTACCTAAGTGTCTCTGAACTGGATTGTCCTCAGGGACAATCTGCTGTAGCCATCAGACTGCACAGAACCAGTGTATGAGAGCTGAAGTGGTGTCTGAAAACACCTGCTTGCCACAGAGTGGGATGCTTCCTGACCCTCAATATTTGATTATTTGCTCTCCACTCCTTCAGAGTAGGGGTGAAATACTCCTTTTTACATTGCTAGGCAATAATGCAAATGTCACTGGAATTATTATTTAAAGAGCAAATTGATCATCCACAAAATGTTTTGCATCTGCATTTTTGGAAGAATGTACAGAAATCCAATAAGAAGGGAAGGCTCTTCACAGATCCTTATTAACTCACAATTTTAGATCAATTTTTAATTAATATTGGAGTTTTAAGAATCATGGAGTTCTGTCTCAAAACTTGACCCCAAGGCCCAAGGTCTAATTTGTCAATCAATTATGCTTTGCTTTTGTCTCCAGTGCTGATAGTGTATGGAGCTGGGATTGACTATCGAAAACCCTGCCTTGGGTACCCCAGTTACCCCAAGGAAGATGCCATGAATCCCACTTTTGCTGGTGGTATGGGACAAGGACTATGCAGAACTGAGTGTCAATATTTCTTTAGGATAAGTCTGCATTTTCAAAAAGAAGTGGAGTGGTGGATCGCTTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATGCAAAATTAGCCAGGTGTGGTGGTGGGCACCTCTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGTGGCAGAGGCTGCAGTGAGCTGAGATCGTGCAACTGCACTCCAGCCTGGGTGACGGATCGAGACTCTGTCTCAAAAAGAAAAAAGAGGTGGAGTGAAGATTGGGTGGAAGAAGAGAAGAACTAGAATAATATCACTTCATCTCCCAGGTTCACATGAAAAATTCAATAATTTAGAAACGGTGAAGAATTGTGTCAACCACTTTTGTAGACTCAATACCTAATATAATTAGGCATTTCAGCAGTTTACAGAATTAAATGCTATTTTATTTATCTGATTGGAAGAAGGGACAAAGGACAATTCAGAGAACAAATGCCCAGTCAAATTGATTACAGATCGTATTTATACTTCAATGAGAAAGCTTTGTAATTTTGAAGTTTGGATTACACTTACAATTTCAATTAAATTGTGTAAAAATACAGATAGATTTCCAGTAAAATAATAATTACCAACATTTGCTCAGTTCTTTCTCAATAAGATACTATTTTAGGCTCAGGTTGAAGTTTCAGCGTTTATCAACGTTCTTGCAAGCGAAGAAAGATAGCTACATTAACAGCGAGCATCCGATTCAGTTGTCTATGCCAGACACACGTCCTGTACCAGTCTTCCTAATCTAGGGAGCCTGGAGGCTTAAACTGTGTTATTAGGTCACTGGTCATACTAAAAAGAGAAACTTAACCCTAATAAAGGCAAAATTGTACTTTTGCAAGGGATTATTTGCAATAGAAATATTTGTTTAGAGGACAAGTCTGTGCTTGTTCTCTACAGGTAGTTTCTCTACCACTATCTAAAGATTCTTGGGCTCATAGTCATATTCACAGTTCCATGGACACATTCTCATGTCTGTGGTCATAATCTCAGGGCCATGGACATAGTCTCTTATCCATAACTATAGTCTCCGGTGCATGGACATATTCTCATGTCTGTGGTCGGAGCCTCAGGGCCATGGATATCATCTCTCATCCGTAAATAGAGTCTCAGGTACATGGACATATTCTCATGCCTGTAGTCAGAGTCTCAGGGCCATGGATATCATCTTTTATCCATAAATATAGACTCAGGTGCATGGACATATTTTTTGGGGTCTGTGACTACTGCTCACAGTTCACGTTCTCTTTCCAGGACTGCTCTATCAGTGAGAACTTGTACCCCATTATTGCTGCAGAAACACGAAGGACGACTTGGTGATCTGGCTTTTCTGTTTTTGAGCACAACAGCAACTAAACCTGACTTCTAAAAACAGTTGTGAAATCCTGATGCCATTTTATTTGCCAATACTATAATACGAGTCAAGCCGTAAGGAAAGAGAACACAAACAAAATGCAATCTATTAATCTTCCAATTGCTGTTTTCACTCTGAAGGCAAAAGCTAGTTTCAGCCTTGATCCCTTTACACAAGAGTAAACTTTGCATATGTATCAATAGAGATAGTTAAGTTCAAATATTTACTGAACACATCACTAATGCACCTAACTCTGAAGGTACATGTGAGAGGGCCAGCAGCAGGTGTAATATGTGATCTCTACTCCCTCCCCACCATCAATTAGCAATCTCATTGGGAGGAGATCTGAAAGTAGAGCTAAGAGGAAGCAAAAAAATAAGCTGACATCTGGATACCTCTGAATCTTCTGACCACCCATACTTTGAGCCATACATACTTGTGAAGGTGTGGATAGTGTGTGCCTGTGACGTGTGCTGGGGTGACTATGTGACCACACCTCAGTAGACCTGAAAGGGGGTAGATTGCATGCTATGTTTGCATAGCCACCAGTGGTGCTGCCCCTCAGTAGACACTGGGAAGTACTGCCAATCCACACTGCTCAAGATTCCAGTGCTCTATAGCCTATGGTAGTGTGCCATGTGCAGTGGCAGGTATACCAGCAACACGACAGACAAGATGTCCTAGAAGAGATTCTACCATGTGGCTTTCCACACTCCCTCCACTGCAGTGGATCCCAAACTAGGTTCTTACCTCAAACTAGGTGGGCCTCAGCAGTGCCCAGTGGTAAGCAAGAGGCCCAGTGGGAGACTCCATTCTCTCCCTGACCCCAGCTTCAAGAGCCACCCCACTTCCACTTGTGTTATGTGCTGGGTTTCCACATGATGATTTGGTTAAAGGATCAGTCAAACATTTAAAGAATGAACACTCTTGCTCTAGTGAGAGGAAAGGCCAAAAATACTAGAGTCTTATGGACATGGGAAGAGAAAAGGGACATATGTGCATGCTTGGTGGGATGACAGCTGTGAATGTGACATGTCCCTCCAGGATCGTAGCATCTGCACGGCACGGCATGGCTCAGGAAAAGCCACTGAAAAGTTGTGGGTTCAGAAGGATCTGGCTACCATGGTGTACCACATATGTACATGCATGTTTGTGCATGCACAAGTCACACACACACCTGCCTGTGGCTGTTTACTAAGACCAGAAAAATGATGGTGAAAAAAAATGAAGCTGACTGCGGTGTCTGTGTGGGTGTTTAGTCAGACTTTTGTCCGATATTCATACTTCAAAACAAGGCAATACTGTTTCAGAAAAATGATTGTGGTATTTTTACATTAAGGTATGTTACAGGAGGGCTTACCCACTTGTATTTATTTTCTATGCTGTGGAACAGATTGCTACAACCTTAACACGTTAAAACAATACAAATGTCTTATCTCATCGTTTCTAAGGGTCAGGCATCCAGGTCTGGTTGAGCTGAGTCCCCTGCTGAGGGTCCGACAGATGAATCACGGTGTGAGCTGGGCCTGTGCCCTCATCTGAGGTCAAGGTCTCCCAGGCTCACAGGATATGGGATCTTTTTTTTTTTTTTTTTTTGTTTGGTTATGAGGCTGGAGTCACCAGCTTCCAGAGGCTGCCTGTTACTCCCTGTCACACCCCCTACAGCATGGTAGCTTCCTTCTTCAGGACCAATAGGAAAGTCTCACATGGCTTCCAATCCCTCTGACCTCTTTTGTCTCTGACCTCCATCTCCTCTTCTAAGGGGCGCATCTGATTAAACCCAGCCCACCCAGGAAACTTTCCTTTTCATTAACTGAAAGTCAAGTGATTAGAACCTCAATGATACCTGAACAAGCCCTTCACCTTTGCCACATGGCACAACCTGCCCATGGGAGGAATCTGTCCATCATAGTAACAGATGCCACACCCATTCAAGGGGAAGGAATCACCCAGGCACATACACTAGAAGGTAAGGATCTTGGGGACCCATTGTAGAATCCTGCCTACCACACAGACACGAATGAAATCATTTTTCCACTCTTGGAAAATCTGTATTGAGGATCTAGTATGTTCCAGATACTGGCCCAGGAACTAAAGATGCAGAGAAACAGGATGGGCATGGTGGGGTTTGCAAGCTAGTGGGGGAGACAGACGTTGATAGATCACCCCTGAGTGGACTGTGTCAAGTGCAATGATGAAGAAGAGTCTCAACAGAGACATGGGAGCCCTGACCTGACCTAAGCTGGTGATCAGGGAAGACTTCCTGGAGGAAATGACGTGTGCTAGAACCTGAGAGATGAGTAAGAGTTGCCAGGAAGAAGGCAGAGGGTGGGAAAAACTCCAGACAGAGGCATCCCAAGGCCCTGGATCATGGCATCCCAAGGGCCCGGGGTGGGAGAAGCAAACCACGTTCAGGGAACTGAAACAGAGCTCAGTGTTGGGGAGCACCATCAGATCAGGGGGAGAGCCCAACTGCTGACCTGTCCTGTCCATGTGGACCTCCAAAGGGCCCATCAAGTGACAGCAGGAAGAGAATTCCAGGTCCTGGTTCTTGCAACTGAGAAGATGATGGGGCCATTTCCTGAGATGGGGCAAGAGAAGCACAGGTTTGGATAGAAGATGGTGAGTGCTGTTGTGACTATGTCGGTCTAAGGTGCCCGTGTGAAACATCTCAGCCAATTGGACACATGAGACACAGAAGCATCTGCAGCTCAGAAGGGATGTCCAGGTGCATTGGAGGAATGTAGAAGAGAGGATTCTCTGAAGGCCACATTCTTTACTGCAATCAATTAAACTTAAATGCAGAACTCCTCTCTATGATGCCCAGGAATTCATGAAAACTTCCCAAGTTTGTTTTGACCTTCATAAGAAAAACTCAGATTACCAAAATGGAATGTGGTCACTAAGAATGTTTCAAGAAAATATGTCCCAGACAGACATATACCGTTTTTTACTCCATCCTATGCCATCTCTGTCTTCTGCAACTCTCAGTGTCTGGTGTTTGTCATTCACCACTGAGTCACAAAGTAAAGGCTAGTATCATTTAGTGACATATAATCCAAGGACATAAGGATGGTTATTAGAGATGATAGCTAGAACTTATTTGGTGCTTACTGTACAGAGAACAATAAATAAATGATTTACATGAATTATCTCTTATAATTCTAACAGTAAAAACATAAGCCAGCACAGTTATTATTGTAGATTTATAAATGAGGGAACTAAAGATTATTAGAGAAGTTAATCAGCTTGTCCAGGACGTGGAACTAAGTGCTAGAGCCGCATGAAACCAGCAGTGAGGCTCCAGGGCCCACACCTTTAAGCTTTATGATGTTGTCCAAACCAGAACTAAAATGTTAAGTTCTAGCTCTGAAAAGATTAGCTCAGTCATCCAGAAAACCTTCCAAAATGCCGTGTTCTTCAACTTATCTATGTTGTTATTTTATTGTACAAAGTTCTAGTAACCATACAAGGAAAGACTGTGTAAGATAGATCATAAATCCATGCAGGAGGAGCCAACTGCGAGTTTAGATGGTGCAGTAAAAGTCCCTTGATCGGCTGTGACACAGGCATGCTCACGGAAATCATCACTTAAAACAAGGAATCACCAAACTTTGCAGTGGCCAGGAAGTACCTGAAATGTTGCATTTTAACTTAAAACATATAAATATGTATTTATTCCCTAATCATTCTCTAATCACATGACTTAGGATCACTTCTTGAAGTTTTGGGTGAAAAGATTGGAGCTCTGTGCCATCTTTTACTCCATGAACTGCATTTAATGTGTAGCATCTGCATTTTTCAACTGGTGTCTCAAGTAAGAGCATGTGACCATTTACCAACGATCTGTTTGCAAATTGGGACAAATCCACATGTCCCATTCTTCTCAGTGGTCCTGACCAAACATAGATCGGCCTTCTTCTTTCTTTCCTTTCTTCTTTCCTTCTTTTCTTCTTTCTTTTCTTTTTTATCCTTCTTTCCTTTTGTCTTCCCTTCTTCCTTCCCTCCTTCCTTCCTTCCTTTCTTTTTTCTTCCCTCTTTCCTTTCTTCCTTCCTTCCCTCCTTCATTCCTTTTGTTCTTCCCTCCTTCATTTCTTTCTCTTTTTAATTTCTTTTCTAACTTACCTCTAAGGAAGGCTTTCCAAAGTAGTCCCATTAACTGTCATAGAAACAGCTTTCTCTTGCACTTGAATTTCATTGGTTTACGTAATTAATTAACTTACAGTACTACCCATGACACGTACAATTGTCACAAACAGGTTGGAAACAAATACAACTGACTCCTCTTCAGCAGCCATTCAACTGGTTGGTGCTAAACTACTTGGCCTCCTAAAGAGAAGCTGTCCAGCAAGAATGTTCACTGTGGTGAACACCAACCAGGGGCTTTATGGAAAGGACTGAGAGTGTTGGCTAAGCTGGGGTGTCTACTAGGATTAAAATCCCCAGGAAACGTTCACTCTGCCCTTGTTGTTCAGGAGGAACCCTGGCAGCTCTGAACTAGGTTGTGGATGTCTTAGACATTACCCTCACCTGATAGAGGTTTGTTCTCAAGGGATTTTTTAACCCAGGATCTATCATTTATGTGTGTTACCTTTTCTAGACCTTCCACTGTTAGCAAGACTTGCCAAAAATGGATTACCAAGATTTTATATTTTCAAATGGTGACTATGTCCAACCCAAGTTAGTTCTCACCAGAGCTCTTGGTTTTGTTATGCAGACTTAGAAGAGTCAAGGTGACGATTATGAGAAGCACATTCAACTCCAAAACAATTTACTGAGCAGTTGCATTGCCATCAAAGCAGTAAAAGACTCACAGATTTCTCCAGGGGCTTGCAAGGGACTTCTATTGGTTTGAATTTCAATGTCTCCATCAATGTGGTTGCCCTCCATATGGACAGTGAGGTTAATGAGAAACAAAGCAAGAGCTCTGATGCCTTCCTCACTGGCACCTTTGACATTTTGGCATCTTCTTGTCTTGGCCATCTCACCCGCCCTCACCTCTTCAACCTGGAAAATAAAAGAACAAGAGGAGTGGGACATGCCTTCAATCTCACTCCCAAATCATGCTTAGTATTGCTGCCACCATGTTCTGCCTTCTTAGCTGGTTTACAGAGGAGAGTTTGTCTTACATGGATACTGTGAATCTTTGACCCAATAATCCCTATTCATCAACAATATTTCCATACCTCTCCTGAGCCCAAAGTGGTGCCATTACAAAATGACTAGGGTGAGGGAGGGTGGGGTCTCTGATGGCTGAGGTAGTTCACCCTCATGCTTCTCAAATTCAGGATCCAAAAGGTTCATCCCCAGTACATTCAAAGCCAAAAACTGCAGCAGAAATGAGACTGATCCAGAAGTTAATTCTCCAGTTATCCAGAGGCAGGAAGTTGCCAGGGGCTGAAATGGGTTGGGAAGACTCCCCAGGACAAGAGGGACTAGAACTGACTGTATTAGGTCCTAGAGCTACAAAGGACCACAGACTCCAACATTAGGAATTTATTTGCTGTCTCTGAGTTCTGGAGGCCAGAAGTCCAAAATCAAGGTGTCTGCAGGGCTGGTTCTCTTTAAGAGCTTTGAGACAAGCATCTGTCCTGGGCTTCTCTCCTTGGCTTATAGATGCCCTCTTCTCCCTGTGTCTTCACATCATCTTCCCTCTATACATGTCTGTCTCTGTGTCCAAACTGGCCCTTTTTATAAGGACACCAGAAGTACTGGATTAGGGACCACCCTAACAAACTCATTTTAACTTGATTACCTCTGTAAAGACCCTACCTCCAATTACAGTGTCATTCTGTGGTCCTGGGGGTTAGGACTTCAACATATGCATTTGGGGGGACACAGCGGAACCCATAACGCTCATCCTGAAAGAGCTGAACAGTAAGTGCGGAGTGGGGTCATGTTGGGAAGCGTGGGTCCGCAAGCCCAAGTTGAGGCCCCACCTTGTGACTAAACACACGGCTCTTCCAG
Seq C2 exon
TTCCAGGTCCTCCCGCGGGTGTGAAGGCAGCGGCGGCCTCAGCCTCCATGGTCTTTGTGTCCTGGCTTCCCCCTCTCAAGCTGAACGGCATCATCCGAAAGTACACTGTATTCTGCTCCCACCCCTATCCCACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000171587-DSCAM:NM_001389:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.151 A=NA C2=0.044
Domain overlap (PFAM):
C1:
PF0004116=fn3=PD(46.6=77.4)
A:
NA
C2:
PF0004116=fn3=PU(50.0=93.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)