HsaINT0052362 @ hg19
Intron Retention
Gene
ENSG00000177103 | DSCAML1
Description
Down syndrome cell adhesion molecule like 1 [Source:HGNC Symbol;Acc:14656]
Coordinates
chr11:117308611-117309699:-
Coord C1 exon
chr11:117309601-117309699
Coord A exon
chr11:117308800-117309600
Coord C2 exon
chr11:117308611-117308799
Length
801 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
ATCAGGCCTACCCTCCGCAGGCT
3' ss Score
6.57
Exon sequences
Seq C1 exon
TTCCCCCGGACCAGCCCCGCCTCACTGTCTCCAAAACCTCAGCTTCGTCCATCACCCTGACCTGGATTCCAGGTGACAATGGGGGCAGCTCCATCCGAG
Seq A exon
GTGAGGAGGGGTCTGGATGCGGGGGAAGATAGGGGAAGGAATTCTGGGCCCGGGGCAGGGAAGGGGCTTCACCCACTTCTGCCATTTGTCTCCAAATGACAGAAACGATCTGGGGGCCAAGTGACCCACAAGGAAGTCACTCAAGTGCCAAGGGAACTGCAATGGCCCAGGCACCTGGGATTTAGTACGCCCGCCCCTCCAATGCCACTTGTGAGCTGTGTGACCCTGGAGTAGGCTGTTTCCCTCTCTGAGTCTGGGTTTCCCAATCTGTCGAAGTAGACAAATGGACTACTAGATCAGTGCTTTCCAAGTGTGGGCGTGCGTCTGCGTCACCAAGGGGCCTTGTAACAATGCAGTTCTGACTCAGCGCTCTGGGCTGGGGCTGAGGACCTGCCTTTCTAACACGCCCCAGGTGCTTCTGAGCCTGCTGCTCAGGGGGCCGTGTCTAGATCCTAGTGAAGATCTAGACAGGACCCCTTGTGAGCCTCACAACTCTGGTTTTCTCCCCTCCCGAACCTGCCGCTAACCCCTAACACTAGAACCAAAGTGACAGCGTCAGACCCGCCGGGGGCTGGACCCCAGGCCCTCACAGTGTTTTGTTGATTGGTTGGTTTAACATAGAGAGTTGACTGGGGCTGATCCTTCCAATTTTGCTTCTAAGGAGCATATGCCCGTTCCAATGACCAAAAGCCTGACTCTGCCCCCTGCCTGGAGCCCAGCCCCCTGTTGGGGTACCTGAGGCTGGGCTTCTGCTGCCTTGCCCTGCCCTGCCCCCACCTGAATCAGGCCTACCCTCCGCAG
Seq C2 exon
GCTTCGTGCTACAGTACTCGGTGGACAACAGCGAGGAGTGGAAGGATGTGTTCATCAGCTCCAGCGAGCGCTCCTTCAAGCTGGACAGCCTCAAGTGTGGCACGTGGTACAAGGTGAAGCTGGCAGCCAAGAACAGCGTGGGCTCTGGGCGCATCAGCGAGATCATCGAGGCCAAGACCCACGGGCGGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000177103-DSCAML1:NM_020693:24
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0004116=fn3=PU(36.9=91.2)
A:
NA
C2:
PF0004116=fn3=PD(61.9=81.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCCCCGCCTCACTGTC
R:
GTGGGTCTTGGCCTCGATGAT
Band lengths:
270-1071
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)