HsaINT0052442 @ hg38
Intron Retention
Gene
ENSG00000134757 | DSG3
Description
desmoglein 3 [Source:HGNC Symbol;Acc:HGNC:3050]
Coordinates
chr18:31469089-31472423:+
Coord C1 exon
chr18:31469089-31469349
Coord A exon
chr18:31469350-31472283
Coord C2 exon
chr18:31472284-31472423
Length
2934 bp
Sequences
Splice sites
5' ss Seq
TGTGTGAGT
5' ss Score
5.84
3' ss Seq
TTTGTTTTGTTTTTCACTAGTGG
3' ss Score
8.06
Exon sequences
Seq C1 exon
CTACCTCGGCCCTCCTCAGAGCCCAGGAACAGATACCTCCTGGAGTATACCACATCTCCCTGGTACTTACAGACAGTCAGAACAATCGGTGTGAGATGCCACGCAGCTTGACACTGGAAGTCTGTCAGTGTGACAACAGGGGCATCTGTGGAACTTCTTACCCAACCACAAGCCCTGGGACCAGGTATGGCAGGCCGCACTCAGGGAGGCTGGGGCCTGCCGCCATCGGCCTGCTGCTCCTTGGTCTCCTGCTGCTGCTGT
Seq A exon
GTGAGTAGCCAATGTTTCATTCTCTGTTGGACCAGGTGTCCTCATTTGCAAAGGCCTCCATGCTGCCCTGCTCATCTGTGCAATGGGGAAAGAATATTCTCTGATGTTTTATAGGTAAAGCTAGGGGAAAATGGCATTTTCAGAAAGAATCTGAAATGTGTAACATGTCGCTTGCTAACAGTCTATATTCATATAGCAACACAAGTTATATATGTCAGACATTTAGAAGACAGCACAAGATAATCAAGAGAAAAGCAAATCATGAAGACTTTCTACACACTGTTAGTAATGTTCATGGTCAAAATTATGGCTTTATCCAAGAGTGTGGCACTTTCTAAGATGTTTTCTCTATATTCATTACATCTCATGAGATTCTAAGATAAAAAGAGAACACTAGTCAAACAAAGTTAGGGAAATACAAATAGGGTATCATAGGCTATTAAGATATCACCACATGCTATTAATATTAATTAATTAATTAACCCCCACTAATATTAATCAATAGCATATGATATTAATATTAATATCATATGCTATTAAGATAGCTAGGTTCTGAGAAGTTATTGCTTCATCTAGCATTTCCTCAAAATAGATTGCCATCTGAATATGCATCCCCTTTAATACTTTCACATTTAATATAACTAAGTTTATTAAACACATTTAGAAAACTATGCGTAAGTATCCTTTTCCAATAAAGGTAAAATTTATTCAATAGATAGGTTTCTGAAAAGTTGTATTTGAATCAAAATCATATAAATCAAATAGTATTTGATTGTAAGAGGTCTCTATTTAAAAGAACTTCCTGACTAATTCTTGTATAAACAAGAGAAATCCTTGCTAAATTCACACTTTCTTAATTTATTATAAAAATCACAGTTTTAGAGTTAAAATTAATTATATGATTATTAATTTTAAAACCACAAAAAGTAGAGAAAATGTGTAGACAACTACACATACAACCATCACTTCAACTGAACAGATATGAATGTTTTGCAATATTTTTTCAGGTCCCTTTTTTTAAAAAGAAATAAATTGCTATAGATACAGCTAATTGCCACACATGCTATATTTTTCCCTTCCTTATTCTCCAAAAGCATTTACTATTCTAAAGTTATTATACACCATTTAGTTTAAGAGCTGAAATTGACACTCAGAGATTTGGTTTTTCAATATCGTATTAATCAAGTTCAAGAACCAGAAATTTTTAAGTACCTCTATGTGAATCACTATGCTAGCTTCTAGCTGAAAAGGAAACTTGATTTTGGTTTTCATGCATGTCTAACTATAGGGGAAAAATACCATGATAAAGCTGTAATAGAAATTACTACAAAGGGGTAATTACAGAACATTTCACGGAATAGAGGAATCATTCAATTGAGCCTTGAAGAATGATTAGGATATAATCAGTATAAAAAATGGAAAAGGCATTTCCAAAAATTGACAGCATCAGCCAAGGCCAGAAAACACTTAGTATTTTCTGTTTTAGGAATCACACAGCCTTCGAAGGCTAAAGCGCGGGGAAATTGTGGAAAGTGAAGGAGCAACAGAGAATGCATTGGGACTAATTTGAAAGGGCTACATACACATGCTGTGGTGTTTGTACTTTATCCTATGAGAAAGAGGAGCTGCTAAAAGCATTTGAATAAAAGACTAACATGATCATATTTGTATTTTAGAAAGACAACCCTGGCAACAGTGTGTACAGTATAACAGTGTAAATTAGAAAGGAAAGAACACTTAAGAGGTCATTGTAAAAGTTCAAGAGAGATGATGAAGGTCAGATTTCGAGCTGTGACATGAGACTGGAAAATAAAGGACAAGTGTGCAGTGCATTACAGTGGCCCCTGGAGAGGATTGGGAGATTAATTGTTATGGTCTGAATGTGTGTGTCCCCCCAAAAAAATTCATATGTTGAAACTTAAACCCTAAAAAAATAGTATTAAGGAGTTGGGCCTTTACCTATATTAATTCAATCCTCATAACAACCTATGATGTAGATACTATTTATTCCCCCATTTTATGGATGAGTTAACTGAGCAAAGAAGGATGATATTACATGCCCAACATTACATAGCTGTTAAGTGGTACAGCCGAAATTTAAACCCTAGAATCTGACTTCGGAGGCTGCATGCTTAAACCCCTCACTAAGCTGCCTCTAAGTGAAGAGAGTTGAAACATTAGGATTCAGGTGGCCTTGGCAGGGCAGAGGTGGCAGTGGGGCCACTGACAACAAAGTGTGGGAAACACCTGCTTTCAAGAATAAGTATTTCACTCTTGGTCAGTTCACATGAGAATGACATTAATCTTTATTGCCAAGGATGTGCACAGAAAGATATTTACGCTGCCAGAAGAGTCCTCCAAGCTTAAGCCACAACTAAGAAATTCTTAAATTACAATTAAGAATGCATTGACAGCCATTGATTAGGCTATCACCCTAGTTACTGAGGGAGTTTTCTGGTTAATTACTGTTTACTGAGAGATAATTAGAGACTAGATTACCAAAACACCATCGTGCCCACCTAAAATCTGGACCATTCTGGTCATATATTTATCTGTGTATTCACCTGACACAATATACATAGCCCCAACATGTGCAAATAAATGCAATAATCATAAAAATGTATTAAGGAAAAGGATTGAGGAGCCAAACAGCCACTTTCATTCATACATCAGTGCCTATTTTAAGAAAATATACCAAAAAAATAACAACAAGAAATGATCTGATCTGTCTCCTTCAGTTTCATAATCACATGAAATTCTAGTGTGCTTACTGTACCAAGTTTCATTTGTAGAAACTAATTTTGGTTTTCATTAGGAATTTTCTACAAATATTTAAGATACTGTATTTTCTTTGTAACATTTCTGAAAAATTATCACATTAAATAGTTCCTAAATTAGTCAAGTGTTCTGATGTTTTGTTTTGTTTTTCACTAG
Seq C2 exon
TGGCCCCCCTTCTGCTGTTGACCTGTGACTGTGGGGCAGGTTCTACTGGGGGAGTGACAGGTGGTTTTATCCCAGTTCCTGATGGCTCAGAAGGAACAATTCATCAGTGGGGAATTGAAGGAGCCCATCCTGAAGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134757:ENST00000257189:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.091 A=NA C2=0.277
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development