HsaINT0054570 @ hg19
Intron Retention
Gene
ENSG00000198759 | EGFL6
Description
EGF-like-domain, multiple 6 [Source:HGNC Symbol;Acc:3235]
Coordinates
chrX:13621436-13624632:+
Coord C1 exon
chrX:13621436-13621555
Coord A exon
chrX:13621556-13624497
Coord C2 exon
chrX:13624498-13624632
Length
2942 bp
Sequences
Splice sites
5' ss Seq
TAGGTACAA
5' ss Score
3.23
3' ss Seq
TTCTGGTTTTTACACCCTAGATA
3' ss Score
7.08
Exon sequences
Seq C1 exon
ACTCTAGGACATGTGCCATGATAAACTGTCAGTACAGCTGTGAAGACACAGAAGAAGGGCCACAGTGCCTGTGTCCATCCTCAGGACTCCGCCTGGCCCCAAATGGAAGAGACTGTCTAG
Seq A exon
GTACAACAGCAGGAATCACCTCTACTCCTCCTTCTCCTCCCTTGACTCCCCTTTTACTGAATCTTTTTTCATTCATCACAATCAGCTTGTTGACTAGACATTGGAAACTTCTAAAAGTACAGATTTATATCAGTTTCTGAGATACTTTTAGCCACATATGCTCTAAACATACTTTGGGATGCTAAAAAACACATTTTTCTATTATTTTGTATTGCCTTAATGCCATAGTAGAAAAGGGATAATTTTAGTATATTTACTATGTACATTTTATTTAAATTACCATCCAATATAAACTCCACTACTTATATTTTGTCATTTAATGAGTAAGGTCCTAAGGACCATTGGGTTTTATTCTGGGTTCTAGCTAATATTTTCTGGAAAAACTATATTTACTTATTTTTTAGATATAACATTATTGAAAATAGTATACACCTTCTATATAATTTACATTAGCATGTAATAAATTTCATGTTGTCTTTAAAACTTGCTCCAAGTTATATGAACTAAGTATAATTAATTTAACTGGAGAAAATGAGCAGATTAAGTCCATAATATTAATTAAGGGAACATAAAAATTATTTGTTTATAACTTTGAATTTAGTCAAATTCATTGGCTTAGAACTTTCCTCTCTTGTTCTCCTTTGTCTTATTTTGTGTCTTAGTTTTGGGTTCCACAGAAGCTGACCCTGAGCAAGTAGTTGATTTGGGAGGTGATCCCAGCCTGAAATCCCAGCCTGAAATTCATTCACTAAGGAATAAAATATTTATTTCACATAGATTAGGGCAATAGCTGACTGGTACCAGAATCTTATGAGTAAGATTCTGGTTGAGGAGTAGGGAAGTAACCCAGGGAAAGGAAGGCACCAGTGTTGGGTAAATCTGATGAGCAGGTTAAATGAGCTGGGGGCACCTCTGGGAGGCAGAGAGAAGCTGCCCCTGAATTTTCCCTCTGGGGCAGGAGTGCTGGATATTCATCCACCAACTTCTGCCCTTCATTGATGGGAGGCTGCTCTGGGACATGACCCCCCAGCACTCCCAGCCTAGCCTGGGTCGGGAGCAAAGCACAATGTTGTAGGTGCAGCAAGCAGCCTTTGGCAGGTATGGAAACTTGAGTGCTGAGGAGCTATGGATGGAGCACCCACAGGGCACCCTCAGTGACTGAAGCAACACTTTTTTCACTTTGTGCTTTGGTTCCTTTGTGGATTTGAATTATGTTCAACCATCAAATTGCCATCAAATTGTATATACTCATAACACTTAATTACATTGCACCTAATATACATAATATTTAGAGTAAGTGAGCACTTAGCATTAATGAGGGATGTCAAACCAAATCAGAATGTTGAAAGAGTTCTTAATCTGTGATTTAAAGAAGCACATATCAGTATGATTTCATAATCTTCTTCACTACAATAGAAATATTTTTCAGTCAAGGTGCTAGATGTTTATTTATCCTAACTATACATAATGTAAAAAAAACTGCATTTAGAAAGCTCAGCCAAATGGATCCTAAATTAGCTAAACACTTTTTAAAAATATACATGTAAATTAAAATTTTGTCTCTACTCTGAGAATAATCAAAGGTTTAATTAGGTTCACAGGATTTACTACTTTTTAGTATAATAAGATTTATATGACAAGGCTAATTATTGACCAAACTGAATCCAAATTTCCACCCAACTCTTTGAGTTGTTGGGTGCCATTTTTATTGGAAGGGAAAGGTGATGTGCATGAAAATGATCACCAAAAATAATTTTGTTCAACCCAACACTTATTTATTATTTGGAAAATGCAAGAGGCCAGCCTGGGCAATATAGCAAGACTCCATCTCTATAAAAAACTTTTGTTAAAAATAGCCGGGCATGGTGATGTGCACCTGTAGTCCCAGCTATGCTAGAGGCTGAGGTGGGAGGATAGCTTGGACTCAGGAGTTTGAGACCAGCCTGAGCAACATAGGGAGACCCCATTTCTACAAAAAAAAAATAATAAAAAATAGCCAGGCATGGTGGCACATGCTTTGTAGTCCCAGCTACTCAGGAGGCTGAGGTGGGAGGATCACTTGAGCCTGGGGAATTTGTGGCTGTAGTGAGCCATGATTGTTCTGCTATGCTCCAGCATGGGTGACAGACCAGGCCTTGTCTCAAAAAAAAAAAAAAAAAAAAGATTGCAAGGGAAATAGTAAGACAACATCAACTTGCCGGTTTAAGCCAGGTTCAGAAGAACAAACTAACATCTATTTGATTTGACATCTGAAAGTTAAACCAAGCCTGAGTCTTAGTAGATTGGTCAGCATAGCTGTCAGCCCCTCTGTTACCTGACTTTCAATGGTAGAAAAGGAACAACACACCTATTGTTGGCTAAAATTACATCATTACATAATTACACCTGACCCACAATTTATGCATAAGTGCATGCCTTCACAACCACATTTCTGTGAGTCAATATTGCAGGGGCCTTGGACAGTCTTACTCAAGAAATAGTTATTTTGTAAAATGCAAATTGTAAAAGTCTGTGTGTTTGGTTTACTTAAAGTATAGCTATCTGACTCTAGTTTCAAAAATTGTATATGTTATACAATATACAATATTCACTCAGCTGGAGAAAATATTCACTCAGCACACACGTAATGTATAGGTACCAAGTGTCAGACACATGCTCCCTGCCTGAGAACAGCCAGGGCCTAACAGAAGATGTGAATGTAAGTAATGACATTATGGAAAGATAATGCATCTTAAAAAGGTATAAAATAATATAAATACATAAAGTGAAGAGCTGTGTGTGTGCCTGGGGGATCTAGAACACTTGCCAGAGGATATGATGTTGGCACCAGTATACTATTATCAGTTTCCCAGATAAAGAAAAGTAGCTGTGAGTGTGCGTGCGTGCATGTATGTGGCTACTTTTCTTGCTATCACTGACACCTTCTGGTTTTTACACCCTAG
Seq C2 exon
ATATTGATGAATGTGCCTCTGGTAAAGTCATCTGTCCCTACAATCGAAGATGTGTGAACACATTTGGAAGCTACTACTGCAAATGTCACATTGGTTTCGAACTGCAATATATCAGTGGACGATATGACTGTATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198759-EGFL6:NM_015507:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=PD(8.9=9.8),PF146701=FXa_inhibition=WD(100=80.5),PF0764510=EGF_CA=PU(0.1=0.0)
A:
NA
C2:
PF0764510=EGF_CA=WD(100=95.7),PF0764510=EGF_CA=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)