HsaINT0056586 @ hg19
Intron Retention
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:3373]
Coordinates
chr22:41554416-41556726:+
Coord C1 exon
chr22:41554416-41554504
Coord A exon
chr22:41554505-41556645
Coord C2 exon
chr22:41556646-41556726
Length
2141 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
3' ss Seq
TATGGCCTTCTTGCCGACAGGTA
3' ss Score
10.14
Exon sequences
Seq C1 exon
TTGGAGTTCTCTCCACAGACACTGTGTTGCTACGGCAAACAGTTGTGCACAATACCTCGTGATGCCACTTATTACAGTTACCAGAACAG
Seq A exon
GTAAGCTTGGCCAGGTGTGGACCATGGTCCATGTGTCCACATGTCCAGGGAGTGCATGCGGATGGGCCAGCACACATACAGTCATGGTTCATGTGTATCTTGCTTGAAGACAGCTGTATAGCACAAGTTCTGTTTTTTGCCTTCTGCCTTTGTTTGCAGAACAATAAAATTTTCTATCAGAGTAGCCTTGCATCAGTTACCTGGGTTCCTCCCAAGAGCTTGAGAAGTTAAGCAACTTTGTGAGTTGTTGGCCTAGATGGGTCTATATCCCAGGCCCCACTTCTCTTTCTACTGTGTGTTTGTTGATCACCACAGCCTGAGGCAAAACTGAGAAGATTTTTAAACTTTTAACTGAAACTCGCTAGACAGCTTTTTGGAAATATTTCCTTTTTAGATGAGGCCTATCCCTAAGTAGTTGTTATTAGAATATATGAAAACAGGATTCTGGAGTCTTTTCTTTGCCTCATATTAAGCAAATTAAAAGGAAAACCTCACATAGCTCTCTGTACCTTACTTTTCCCAACCCAGCCTTGTATGTGACAGAGGATGATTTGAGTCTAATAAACGAGGCACCTCTGCCTAATTTTCTCCTGCCCAATCAATGGCTGTAATCACATAAATCTCATTCACTAATCTATCTTAACCACAATTTGTCTCCTGTTTTCAGTGATCAGCTACAAGTATAGCTTGCATTGGGTGTTTATTTGGGGCTCTGATACAATAATAACAAGGCTGGATGATATTAATACCCTTTATTTGTTTGTTAATACCAAATCCATGGTGTTGGTTTTTGCTGAACTTGTGTGTTGCAGATGCATTTCTAGCTTTGAAAAGTCACTTAAACTTTTTCTTTTATTTACAAAAAGTTAGGCGTGCTTCTAATGCTTTGTAGACCTAATGCTTTGATTTTGCAGTGAGTAAAAATCTAGCTCTTTACTCATTTGAAACCTAGAAAAGGTGGGACTCAAGTTGTTATAAGTACCTTATGTTTAAAAAAGCAAGTAACTGGACATGAAACTTTTCTCATGTTTACTAAAACAGTAGTCTAAAGTGTTTATCTTTGCACCAAGCCATCTTTAATCAGGTACCTGCACACATCATTTCCTTTTGAAATGTATCACTTGATGGCTGTAGTCAGTATTTAACTGCTTGTGCAGGCTTTTCAATAAACAGTTTTTTTTCTTTCTTTGTTGAGACAGGGTCTCACTCTGTCACTCAGGCTGGAGTGCAGTGGCGCAATCTTAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTTCCAAATAGTTGGGATTACAGGTGTGTGCCACCATGCCTTGCTTATTTTTGTATTTTTAGTAGAGACAGGGTTTCAGCATGTTGGCCAGGCTGGTCTCGATCTCCTGACCTCAGATGATCCACCCTCTCAGCCTTCCAAAGTGCTAGGATTATAGGTATGAGCCACCACGCCTGGCAATGGTTGTTTTAGATTATTGTTTTCTGCAGTTGTATCTATAGTGGGCTTTTGGGGTGGGGGGTGGGGGTCTGTGGTTTTTTGTTTTGTAAGTGGGAAGAGGTGTGATTCCTGTATTTAGGTAATGAGTAGCAGTTCTTCTCTCCCTGGTATATTTATCCTTCTTCCTCCTTTTGATTATTTACATCACATAGCGTTAATTGCTGAAATGAAAGGATATGGGTCTGTGTAATTGAAACATTTGCTTTTATTTGCAGTAATCATTTGCTACTTGTGATCCCATTTGAGATATTTAATGCTAATCTGTGCTTTGCCTTGGCTTTCTGCTTTGTGTTGTTCTGTCTTGCTTTTATGTTTTTTGTTGTCTTGCAATCCCTCATTTCTTCGTTTGTTTTGTGTTTTTTTTTCTCCCTCATGCTTGTCGTTGTCTGCACTTGGCTTTGATTGCAAAAAAAAAAACAAAAAAAAACAAAAAAACAAACAAAAAAACCAAAACCCAAACTGTGGGGCCCATATATCTGCATCATTGAATGTCCTTGTCGCCGTTGATGACCTGCTCTCTGCTCCCGTCCCCCTCCTTGGCCTGCTGTGATTGGTGGCTTCGTTGCTTGGCTTGGGCTGTGTTGTGTGAACGGAACAGTTCACCCCAGTATGGCCTTCTTGCCGACAG
Seq C2 exon
GTATCATTTCTGTGAGAAGTGTTTCAATGAGATCCAAGGGGAGAGCGTTTCTTTGGGGGATGACCCTTCCCAGCCTCAAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393-EP300:NM_001429:19
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.286
Domain overlap (PFAM):
C1:
PF060018=DUF902=PD(66.7=93.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)