HsaINT0059110 @ hg38
Intron Retention
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]
Coordinates
chr4:186280223-186280580:+
Coord C1 exon
chr4:186280223-186280385
Coord A exon
chr4:186280386-186280473
Coord C2 exon
chr4:186280474-186280580
Length
88 bp
Sequences
Splice sites
5' ss Seq
GAAGTAAGC
5' ss Score
6.95
3' ss Seq
CGTTTTGTTTCCAACTGCAGGGG
3' ss Score
9.37
Exon sequences
Seq C1 exon
TGTTCTGCCATTCTTCATTTTACCATGACACTGATTTCTTGGGAGAAGAACTGGATATTGTTGCTGCAAAAAGTCACGAGGCCTGCCAGAAACTGTGCACCAATGCCGTCCGCTGCCAGTTTTTTACCTATACCCCAGCCCAAGCATCCTGCAACGAAGGGAA
Seq A exon
GTAAGCCATATGAAGGGTTATGCAGACACCCTTGTCCCGTCTGCCTGTGAGGTGCATTATGTTTATACCGTTTTGTTTCCAACTGCAG
Seq C2 exon
GGGCAAGTGTTACTTAAAGCTTTCTTCAAACGGATCTCCAACTAAAATACTTCACGGGAGAGGAGGCATCTCTGGATACACATTAAGGTTGTGTAAAATGGATAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926:ENST00000403665:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF142951=PAN_4=PU(86.3=80.0)
A:
NA
C2:
PF142951=PAN_4=PD(11.8=16.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAAAAAGTCACGAGGCCT
R:
GCCTCCTCTCCCGTGAAGTAT
Band lengths:
167-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development