HsaINT0059121 @ hg19
Intron Retention
Gene
ENSG00000131187 | F12
Description
coagulation factor XII (Hageman factor) [Source:HGNC Symbol;Acc:3530]
Coordinates
chr5:176830482-176831091:-
Coord C1 exon
chr5:176830860-176831091
Coord A exon
chr5:176830619-176830859
Coord C2 exon
chr5:176830482-176830618
Length
241 bp
Sequences
Splice sites
5' ss Seq
CCGGCGAGT
5' ss Score
3.14
3' ss Seq
CTCCCCTACCCCCCCCGCAGGCC
3' ss Score
11.59
Exon sequences
Seq C1 exon
CCTTGCCGGCGAAGCGGGAGCAGCCGCCTTCCCTGACCAGGAACGGCCCACTGAGCTGCGGGCAGCGGCTCCGCAAGAGTCTGTCTTCGATGACCCGCGTCGTTGGCGGGCTGGTGGCGCTACGCGGGGCGCACCCCTACATCGCCGCGCTGTACTGGGGCCACAGTTTCTGCGCCGGCAGCCTCATCGCCCCCTGCTGGGTGCTGACGGCCGCTCACTGCCTGCAGGACCG
Seq A exon
GCGAGTACCCGCCCGCCCAGAGCCGCCCCAGGGGCCGCGGCTCCTCCGTCTCCCAGCGCAGCTTCCACGCTGCACCCGAACCCGTGCCCTACCTTCTCCCGCCCCACCCTTCTTTCCACGCCCCTCCGGAGCTCCCGGGGAGGAAGCTGGAACACGGGATTGGGGTTCGGGAGCAGGGGGCTTCCCCAGAACGCTTGTGGCCAGGTCTGAGAGCGCTGCCTCTCCCCTACCCCCCCCGCAG
Seq C2 exon
GCCCGCACCCGAGGATCTGACGGTGGTGCTCGGCCAGGAACGCCGTAACCACAGCTGTGAGCCGTGCCAGACGTTGGCCGTGCGCTCCTACCGCTTGCACGAGGCCTTCTCGCCCGTCAGCTACCAGCACGACCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187-F12:NM_000505:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.218 A=NA C2=0.064
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(18.6=56.4)
A:
NA
C2:
PF0008921=Trypsin=FE(19.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTCCGCAAGAGTCTGTCTTC
R:
CAGGTCGTGCTGGTAGCTGA
Band lengths:
301-542
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)